Johnson & Johnson

Principal Solution Architect

Johnson & Johnson$150K — $180K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 5+ years in solution architecture or systems integration
  • Experience in delivering large, distributed, data-driven platforms
  • Preferred experience in life sciences or pharma R&D
  • Strong background in cloud-native architectures
  • Familiarity with AI/ML platforms and laboratory systems

Responsibilities

  • Design and govern modular solution architectures for data integration
  • Architect closed-loop data generation and AI-ready data pipelines
  • Lead systems integration for lab automation and enterprise platforms
  • Collaborate with scientific teams to translate workflows into technical solutions
  • Ensure architectures comply with cybersecurity and regulatory standards

Benefits

  • Opportunity to impact high-priority health initiatives
  • Collaborative environment valuing architecture skills
  • Supportive culture for professional growth
  • Participation in cutting-edge technology applications
  • Engagement with a mission-driven organization to enhance patient care
Full Job Description
Job Function:
Technology Enterprise Strategy & Security

Job Sub Function:
Solution Architecture

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

Principal Solution Architect

We are seeking a Technical Solution Architect to join our Solution Architecture organization in Spring House, PA.

This role will be instrumental in designing and delivering critical components of an end-to-end drug discovery engine, a pivotal initiative redefining how differentiated therapies are discovered.

The architect will collaborate on a scalable, fit-for-purpose end-to-end technology stack supporting a Design-Make-Test-Learn (DMTL) closed-loop system, using AI, automation, and proprietary data to accelerate discovery outcomes.

The impact of this role is significant and far-reaching, directly contributing to the transformation of drug discovery through advanced technology and data-driven innovation. By designing and enabling key components of the discovery engine!

Key Responsibilities
  • Solution & Component Architecture. Design and govern modular solution architectures ensuring seamless data and workflow integration. Define integration patterns across platforms such as LIMS, SDMS, data platforms, and AI/ML systems
  • Data & AI Architecture Enablement. Architect solutions enabling closed-loop data generation and feedback cycles across discovery workflows. Support design of AI-ready data pipelines, ensuring data quality, lineage, and accessibility and enable integration of AI/ML models and agentic tools into discovery processes
  • Integration & Platform Engineering. Lead architecture for systems integration across lab automation, laboratory systems, and enterprise platforms, define patterns for event-driven workflows, orchestration, and observability in automated discovery pipelines. Collaborate with engineering teams (cloud, data, ML Ops) to deliver robust, scalable solutions
  • Collaboration with Scientific & Engineering Teams. Partner with scientists, data engineers, AI researchers, and lab automation teams to translate scientific workflows into technical solutions. Co-design solutions that enable AI-augmented science and decision intelligence
  • Governance, Security & Compliance. Ensure architectures align with cybersecurity, data governance, and regulatory standards. Embed secure-by-design principles, particularly in the context of AI and sensitive discovery data

Required Qualifications
Experience:
  • 5+ years in solution architecture, platform architecture, or systems integration
  • Proven experience delivering large, complex, distributed, data-driven platforms
  • Experience in life sciences / pharma R&D environments (preferred)

Technical Expertise

Strong background in:
  • Using GenAI tools to facilitate and deliver the architecture design
  • Cloud-native architectures and distributed systems
  • API-led and event-driven integration patterns
  • Data platforms (e.g., Snowflake or equivalent AI-ready data systems)

Familiarity with:
  • AI/ML platforms and MLOps ecosystems
  • Laboratory systems (LIMS, SDMS) and lab automation environments
  • Data engineering and ingestion pipelines

Domain Knowledge (Preferred):
  • Understanding of drug discovery workflows (Design-Make-Test-Learn)
  • Awareness of automation in laboratory environments and data generation pipelines

Key Competencies:

The candidate demonstrates strong systems thinking, with the ability to design solutions across complex and highly interconnected domains. They bring deep expertise in abstraction and modular design, enabling the creation of scalable, component-level architectures that integrate seamlessly into broader platforms.

The role requires excellent engagement skills, fostering effective collaboration across scientific and technical teams to translate complex requirements into actionable solutions. Appetite for innovation is essential, with comfort in working with emerging AI and automation technologies, combined with a clear execution focus to deliver high-impact results within bold timelines.

What we offer:

The opportunity to work on high-impact initiatives in a world-class healthcare organization, improving experiences for patients, customers, and colleagues. A collaborative, supportive environment where your architecture skill and curiosity are valued.

Bring your architecture craftsmanship to a mission that matters and help us build technology and services that improve care for patients and customers across the world.

#JNJTech

#LI-Hybrid

Required Skills:

Preferred Skills:
Change Management, Coaching, Consulting, Critical Thinking, Emerging Technologies, Enterprise IT Governance, Information Security Management System (ISMS), Information Technology Strategies, Information Technology Trends, IT Architecture, Organizing, Presentation Design, Product Configuration, Project Reporting, Report Writing, Requirements Analysis, Solution Architecture, Technical Credibility

About Johnson & Johnson

Scio Diamond creates single-crystal Type IIa diamonds for the jewelry market and for industrial applications. It employs a patent-protected chemical vapor deposition (CVD) process in a precisely controlled laboratory setting to produce diamonds. It was founded in 2009 and is headquartered in Greenville, South Carolina.

Johnson & Johnson Careers

Joining Johnson & Johnson provides an unparalleled opportunity to be a part of a global team of professionals dedicated to blending care, science, and innovation to profoundly change the trajectory of health for humanity.

Work You’ll Do

At Johnson & Johnson, you will engage in work that matters. Join our community of professionals in health care to drive significant and impactful changes across the globe. Our team at Johnson & Johnson leads with science and heart in sectors from pharmaceuticals to medical devices and consumer health products.

Transform Health Care

Leverage Johnson & Johnson’s culture of innovation to transform health care and improve the lives of people around the world. Our collaborative environment encourages leadership and growth, allowing you to pioneer new strategies for health care solutions with a diverse team of experts.

Innovative Work

Engage in groundbreaking work that enhances how care is delivered on a global scale. Johnson & Johnson’s commitment to innovative health solutions results in dynamic career paths filled with opportunities for professional growth and development.

Be Part of a Great Team

Our team at Johnson & Johnson thrives on collaboration and diversity. You will work alongside over 130,000 employees globally who are committed to making a lasting impact. With a culture that values diversity training and leadership, you are supported in both personal and professional growth.

Future-Proof Your Career

Johnson & Johnson offers a myriad of job opportunities and employment benefits designed to help you meet your career and personal goals. Our employees enjoy comprehensive benefits, including health insurance, retirement plans, and family-friendly policies that pave the way for a fulfilling career and life balance.

Explore Job Opportunities and Internships

Whether you’re looking to start your career or take it to the next level, Johnson & Johnson offers positions ranging from internships to leadership roles across various sectors. Enhance your skills through hands-on experience and our extensive networking and mentorship programs.

Johnson & Johnson Leadership and Development

Our commitment to leadership and continuous learning is at the core of our employment philosophy. Every position offers chances to lead, learn, and innovate. We provide extensive training programs and development courses that prepare you for the future of health care.

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Learn more about Johnson & Johnson
Size
141,700 employees
Market Cap
$462.7 billion
Industry
Net Income
$14.7 billion
Founded
1886
5 Year Trend
+5.5%
Revenue
$82.5 billion
NASDAQ

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