AbbVie

Principal Research Scientist I, Multispecifics Engineering

AbbVie$120K — $150K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD or MS in Biochemistry, Biochemical Engineering or related fields.
  • 6+ years (PhD) or 12+ years (MS) in multispecific or antibody engineering.
  • Experience in design, expression, and purification of multispecific biologics.
  • Deep understanding of multispecifics in therapeutic areas such as immunology, oncology, and neuroscience.
  • Excellent organization and project management skills.
  • Strong verbal and written communication capability.

Responsibilities

  • Design, engineer, and produce multispecific biologics for various therapeutic areas.
  • Serve as a representative in cross-functional teams for project updates and expert advice.
  • Coordinate activities as the Biologics Lead from hit generation to candidate nomination.
  • Independently identify and solve technical challenges with innovative ideas.
  • Ensure quality and consistency in technical reporting.
  • Present research findings and contribute to scientific publications and patents.

Benefits

  • Paid time off including vacation, holidays, and sick leave.
  • Comprehensive medical, dental, and vision insurance.
  • 401(k) plan eligibility with company contributions.
  • Opportunity to participate in long-term incentive programs.
Full Job Description
The Multispecifics Engineering group at AbbVie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting Discovery Biotherapeutics. This position will impact projects through engineering, production, and characterization of multispecific biopharmaceutical products. The ideal candidate should have extensive experience with biologics and multispecifics production platforms, analytical characterization, and a proven track record implementing multispecific engineering and production strategies to advance early- and late-stage discovery programs. The ideal candidate will also have people and project management experience. The applicant should be an enthusiastic, creative scientist who will make tangible contributions to the pipeline. Key responsibilities: - Responsible for design, engineering, and production of multispecific biologics supporting multiple therapeutic areas - Serve as a Multispecifics Engineering representative in cross-functional teams including the Therapeutic Area, Discovery Biotherapeutics, and Development Sciences, providing project updates, analysis, and advice; recognized expert in multispecific design and production - Serve as the Biologics Lead on projects to coordinate activities and transitions from hit generation through candidate nomination - Identify and solve technical problems independently, conceive and implement innovative research ideas - Ensure consistency and quality of technical reports - Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents Qualifications - PhD or MS degree in Biochemistry, Biochemical engineering or related disciplines - 6+ (PhD) or 12+ (MS) years of experience in multispecific engineering or antibody engineering - Experience with protein, biologics, fragments, or multispecifics (e.g. bispecifics, trispecifics, bispecific protein fusions) design, expression and purification - In-depth knowledge of the multispecific landscape, trends in design, and application across therapeutic areas including immunology, oncology, and neuroscience - Ability to recognize emerging areas of interest in multispecific engineering, antibody engineering, and related fields, and make connections between research ideas to advance platforms and programs - Excellent organizational skills and the ability to manage multiple projects simultaneously - Team player with the ability to operate in a fast-paced multi-disciplinary environment - Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude - Preferred qualifications: - Experience with sequence analysis tools (Vector NTI, Geneious, Genedata) - Experience with mass spectrometry analysis and software (Protein Metrics) - Experience with CRO coordination for production - Expert understanding of current state of protein expression/separation/analytical technologies - Extensive knowledge of biologic pipeline progression from exploratory through candidate nomination with program management experience preferred - Experience managing direct reports and providing performance evaluations and development opportunities - Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: - The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future. - We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. - This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

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AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

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Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ

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