Position Summary

The Principal Program Manager, Engineering Projects leads a portfolio of complex capital, facility, utility, equipment, and technical-infrastructure programs that enable ImmunityBio's clinical and commercial GMP manufacturing operations. This role provides strategic program leadership from concept development and capital approval through design, construction, commissioning, qualification, operational handover, and closeout. The Principal Program Manager establishes integrated governance, portfolio priorities, execution strategy, project controls, and executive decision support; leads cross-functional internal teams and external engineering, construction, CQV, and vendor partners; and ensures programs are delivered safely, compliantly, on schedule, within approved capital budgets, and in alignment with business, quality, and regulatory requirements.

Essential Functions

• Lead a portfolio of capital, facility, utility, equipment, and technical-infrastructure programs that enable clinical and commercial GMP manufacturing, from concept and business case through construction, CQV, operational turnover, and closeout
• Establish the program strategy, integrated roadmap, governance model, decision cadence, portfolio priorities, resource plan, and performance measures in alignment with business objectives.
• Develop and maintain integrated project controls, including scope, WBS, schedule, critical path, cost forecast, cash flow, resource requirements, risks, assumptions, dependencies, changes, and mitigation plans.
• Lead cross-functional delivery across Engineering, Facilities, Manufacturing, Quality, Validation, EHS, Supply Chain, Finance, Procurement, and external architecture, engineering, construction, and equipment-vendor partners.
• Integrate GMP, Quality, and CQV requirements into project plans, including design qualification where applicable, commissioning, IQ/OQ/PQ, documentation review, deviation/change-control dependencies, and readiness for release to operations.
• Provide executive-ready portfolio reporting, decision briefs, scenario analyses, risk escalations, and recommendations on scope, schedule, cost, capacity, and compliance tradeoffs.
• Direct capital planning and financial controls, including business cases, appropriation requests, budget baselines, forecasting, cash-flow management, invoice review, vendor performance, and change-order governance.
• Establish and continuously improve scalable project-management standards, tools, dashboards, SOPs, templates, and lessons-learned practices across the Engineering Projects portfolio.
• Establish project closeout and operational-handover requirements, ensuring equipment, facilities, utilities, documentation, training, maintenance strategies, and quality deliverables are complete and accepted by the receiving operating function.
• Ensure capital-project execution is integrated with applicable quality-system processes, including change control, quality risk management, deviation/CAPA support, document control, and inspection readiness.
• Provide functional leadership, coaching, and mentorship to project managers and project-team members; promote consistent program-management practices across the Engineering Projects organization.
• Lead project readiness for internal and external audits and inspections; coordinate project evidence and subject-matter experts, present project execution and CQV status as appropriate, and support timely responses to observations.
• Perform ad-hoc and cross-functional duties and/or projects as assigned to support business needs and provide developmental opportunities.

Education & Experience

• Bachelor's degree in engineering, science or relevant field required.
• 10+ years of progressively responsible experience leading engineering, facilities, manufacturing, validation, or capital-project programs, including at least 6 years managing complex projects in a GMP-regulated biopharmaceutical, pharmaceutical, medical-device, or similarly regulated manufacturing environment is required.
• Experience delivering capital projects through design, construction, commissioning, qualification, operational handover, and closeout, including ownership of scope, schedule, budget, risk, contractor coordination, and change control is required.
• Experience with facility buildouts and equipment CQV strongly preferred.
• Experience leading capital or infrastructure projects involving construction, utilities, and equipment installation in cGMP or similarly regulated environments preferred.
• Experience working with cross-functional teams, external design and construction partners, and multiple stakeholders in a matrixed organization preferred.
• PMP or other project management certification preferred.

Knowledge, Skills, & Abilities

• Demonstrated executive presence, strategic judgment, influence without authority, conflict resolution, and the ability to translate technical, regulatory, schedule, and financial information into clear decisions and recommendations.
• Demonstrated knowledge and application of stage-gate, predictive, and hybrid project-delivery methodologies appropriate to regulated capital, engineering, and CQV environments.
• Exceptional written, verbal, and presentation skills across technical, operational, quality, contractor, and executive audiences.
• Strong experience facilitating project team meetings, cross-functional communication and decision making, and ensuring alignment with internal and external stakeholders.
• Ability to work effectively with cross-functional teams in a highly matrixed organization
• Demonstrated ability to think strategically when planning, managing teams, and managing processes.
• Solid understanding of facility and utility systems (e.g., clean utilities, process gases, HVAC, process equipment) and their impact on GMP operations.
• Working knowledge of commissioning and validation principles, including development and execution of IQ/OQ/PQ protocols and related documentation.
• Ability to manage multiple projects and priorities simultaneously while maintaining attention to detail and compliance.
• Proficiency with project management tools and MS Office (e.g., MS Project or equivalent, Excel, PowerPoint, Word); familiarity with CAD or BIM tools is a plus.

Working Environment / Physical Environment

• This position works on site as noted in the offer letter.
• Regular work schedule is Monday - Friday, within standard business hours. Flexibility is available with manager approval.
• Must possess mobility to work in a standard office setting and in construction/plant environments, and to use standard office equipment, including a computer.
• Lift and carry materials weighing up to 20 pounds.

This position is eligible for a discretionary bonus and equity award. The annual base pay range for this position is below. The specific rate will depend on the successful candidate's qualifications, prior experience as well as geographic location.

$148,500 (entry-level qualifications) to $165,000 (highly experienced) annually

The application window is anticipated to close on 60 days from when it is posted or sooner if the position is filled or closed.