Principal Engineer for St. Louis, MO to lead IT project strategies in software architecture & development of digital, data, and AI solutions, leveraging cloud-native, event-driven, and serverless architectures; lead teams in implementing & operating secure, scalable, and resilient architectures for automation, observability, and self-service platforms; design & implement real-time data, analytics, and AI solutions; mentor & train engineers. Requires Master's degree in C.S., Software Engineering, Electrical Engineering or closely related field & 3 yrs experience in a consumer health, life sciences and/or pharmaceutical environment: designing & operating GxP Lakehouses in compliance with 21 CFR Part 11 and EudraLex Annex 11 using AWS Sagemaker Unified Studio, Databricks, and Microsoft Fabric; implementing Zero-Trust and Governance-as-Code to automate security controls; using Terraform to automate Installation Qualification and Operational Qualification documentation within CI/CD and/or DevSecOps pipelines and regulatory workloads; designing & implementing real-time Agentic AI strategies and life sciences business flows for autonomous reasoning and RAG implementations; scaling AI-MLOps using SageMaker, EKS, and/or Databricks, including Federated Learning & Explainable AI for clinical validation; leading application of Differential Privacy, Safety & Federated Learning to patient datasets for cross-border AI training; managing engineering delivery & excellence within Global Capability Centers. Telecommuting permissible from home office location within reasonable commuting distance of St. Louis, MO up to 2 days per week. Up to 20% U.S. and int'l travel req'd. Salary Range: Employees can expect to be paid a salary between $190,000.00 to $225,000.00. Additional compensation may include a bonus or commission (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc. The offered salary may vary within this range based on an applicant's location, market data/ranges, an applicant's skills and prior relevant experience, certain degrees and certifications, and other relevant factors. Mail resume to Jill Martin, Bayer U.S. LLC, 800 N. Lindbergh Blvd., E2NE, St. Louis, MO 63167 or email resume to [email protected]. Include reference code below with resume. Location:United States : Missouri : St. Louis Division:Enabling Functions Reference Code:873561 Contact Us Email:[email protected]