Pursuant to Section 20 C.F.R. 656.10, you are hereby notified that an application for Alien Employment Certification will be filed by Shire Human Genetic Therapies, Inc. for the following job opportunity: JOB LOCATION: Lexington, MA POSITION: Principal Automation Engineer POSITION DESCRIPTION: Shire Human Genetic Therapies, Inc. is seeking a Principal Automation Engineer with the following duties: responsible for operational, project, and strategic support of PLC, DCS, Manufacturing Execution systems, and ancillary data systems used to control and collect data for various building and manufacturing unit operations. Main manufacturing systems include: incubators, bioreactors, chromatography skids, filtration skids, media and buffer preparation vessels, intermediate totes, CIP and caustic distribution skids, COP washers, and autoclaves; provide technical leadership and contribute to the strategic vision of the Automation Engineering group, which supports the equipment and systems in the cGMP manufacturing of commercial and clinical products at Takeda MBO sites; develop and maintain design and fabrication standards for low voltage control panels, instrumentation communication protocols, and overall maintainability of our control hardware by our I&C technicians; accountable for system performance, continuous improvement, system and software platform upgrading, life cycle planning and large-scale and strategic innovation; serve as industry and company recognized subject matter expert on multiple assigned unit operations across multiple platforms; support and lead tasks and activities related to project engineering, including large and transformational projects; serve as consulting to automation engineering and site leadership on major functionality challenges and industry best practices pertaining to design, policies, business processes, goals, and objectives; oversee technical output of full-time engineers, contractors and vendors. Up to 20% domestic and international travel required for project factory acceptance tests and industry meetings and conferences. Up to 20% remote work allowed. The estimated salary range reflects an anticipated range for this position. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. REQUIREMENTS: Bachelor's degree in Electronics Engineering plus 12 years of related experience. Prior experience must include: scope, engineering, program, implement, commission, operate, maintain, optimize, administrate large scale control systems over 100K DST (input/output control signals); control system life cycle planning; control system Major version hardware and software upgrade; system and control performance improvement and control optimization; virtualize and deploy control system with virtualized host infrastructure; integrate third party software and hardware with control system; develop and maintain control panel standard; integrate bused devices for different protocols and managed site instruments assets; coded control applications and configured HMI graphics; carry out ICS system Cyber security evaluation and consultation, recommended cyber security enhancement solutions, execute solutions; develop and maintain control system SOP, maintenance standard and procedures; solve across platform, system, communications, controls, device levels problems. Full time. $159,390 to $242,550 per year. Locations USA - MA - Lexington - BIO OPS Worker Type Employee Worker Sub-Type Regular Time Type Full time