Posting Details

Posting Summary

Logo

Posting Number
STA00724PO26

Job Family
Research

Job Function
Research Laboratory Management

USC Market Title
Research Laboratory Manager

Link to USC Market Title
https://uscjobs.sc.edu/titles/180403

Job Level
R2 - Research

Business Title (Internal Title)
Organoid and Biofabrication Core Manager

Campus
Columbia

Work County
Richland

College/Division
Office of Research

Department
OOR Research Cores

State Pay Range
Unclassified

USC Market Range
MRK - $86,515 $110,307 $134,098

Anticipated Hiring Range
$86,5150-$100,000

Location of Vacancy

Part/Full Time
Full Time

Hours per Week
37.5

Work Schedule

• Standard working schedule: 8:30am - 5:00pm
• Must be willing to work a flexible schedule to meet the needs of the department.

Basis
12 months

Job Search Category
Other Professional

Position Description

Advertised Job Summary

The University of South Carolina is seeking to hire a Core Manager to provide scientific and operational leadership for the Organoid and Biofabrication Core, a division of the Instrumentation Resource Facility (IRF) within the Office of the Vice President for Research. The Core will provide fee-for-service, collaborative research support, and instrument access for organoid models, induced pluripotent stem cell (iPSC)-based models, tissue engineering, bioprinting, and related biofabrication applications.

The Core Manager will lead the day-to-day scientific and operational activities of the division and will work directly with investigators to translate research questions into practical, reproducible experimental workflows. A central responsibility of the position is understanding and integrating both upstream and downstream processing for advanced cell-based models, including mammalian cell culture, cell expansion and differentiation, organoid and iPSC workflows, biofabrication, sample preparation, phenotypic characterization, flow cytometry, fluorescence microscopy, and quantitative analysis. The Manager will collaborate with other IRF divisions and institutional partners to connect these technologies into comprehensive research workflows.

Job Related Minimum Required Education and Experience

• Requires a Doctoral (Ph.D.) degree in area of research specialty.

Required Certification, Licensure/Other Credentials

Preferred Qualifications

• Doctoral degree in cell biology, molecular biology, biomedical engineering, bioengineering, biotechnology, stem cell biology, tissue engineering, or a closely related discipline.
• Demonstrated hands-on experience with mammalian cell culture and advanced cell-based research models, including organoids, stem cells/iPSCs, tissue engineering, and/or biofabrication.
• Experience with bioprinting or a closely related biofabrication technology.
• Demonstrated ability to independently develop, optimize, troubleshoot, and document biological or bioengineering protocols.
• Demonstrated knowledge of upstream and downstream processing for advanced cell-based models, with working knowledge of flow cytometry and microscopy as complementary characterization methods.
• Experience with human iPSC culture and differentiation, organoid model development, and/or other advanced three-dimensional cell culture systems.
• Experience with bioprinting, tissue engineering, biomaterials, bioinks, or related biofabrication technologies.
• Experience applying flow cytometry, fluorescence/confocal microscopy, image analysis, or other analytical methods to characterize cells, organoids, or engineered tissues.
• Experience working in a centralized research core, shared-resource facility, or multidisciplinary research environment, including development and implementation of new research services or standardized workflows.

Knowledge/Skills/Abilities

• Working knowledge of mammalian cell culture, aseptic technique, cell expansion, cryopreservation, and organoid and stem cell/iPSC model systems, including their differentiation, maintenance, and experimental use.
• Knowledge of tissue engineering and bioprinting/biofabrication workflows, including biomaterials and bioinks, construct handling, post-fabrication culture, and troubleshooting.
• Demonstrated understanding of integrated upstream and downstream workflows for advanced cell-based models, with working knowledge of flow cytometry and fluorescence/confocal microscopy for sample preparation, characterization, imaging, analysis, and interpretation.
• Ability to develop, optimize, validate, standardize, document, and troubleshoot complex biological protocols and shared-resource services, including quality assurance, quality control, reproducibility, and SOP development.
• Ability to assess experimental feasibility, recognize technical limitations, recommend appropriate workflows or complementary analytical approaches, and train users with varying levels of technical expertise.
• Strong communication, collaboration, organizational, and administrative skills sufficient to work with investigators, technical staff, vendors, and institutional stakeholders while managing service requests, scheduling, documentation, and concurrent projects.
• Ability to create iPSCs from somatic cells.

Job Duties

Job Duty

Scientific and Operational LeadershipDirect the day-to-day operations of the Organoid and Biofabrication Core. Maintain operational readiness of cell-culture and biofabrication spaces; oversee biofabrication and organoid performance, preventive maintenance, troubleshooting, and repair in coordination with vendor technical support; maintain appropriate supplies and inventories; establish and monitor quality-control practices; and support compliance with applicable institutional safety and laboratory requirements.

Essential Function
Yes

Percentage of Time
25

Job Duty

User Consultation, Training, and Integrated Research Support

Consult with internal and external investigators on experimental design, feasibility, sample requirements, and appropriate use of Core technologies. Train users in relevant organoid, iPSC, cell-culture, tissue-engineering, and biofabrication workflows. Provide scientific troubleshooting and help investigators integrate upstream culture and fabrication processes with downstream characterization approaches, including flow cytometry, fluorescence microscopy, image analysis, and related analytical methods.

Essential Function
Yes

Percentage of Time
20

Job Duty

Protocol, Model, and Service Development

Develop, optimize, validate, document, and implement new organoid, iPSC, tissue-engineering, bioprinting, and biofabrication protocols and services. Establish standardized workflows, acceptance criteria, quality-control measures, and reproducibility standards. Adapt research protocols for reliable use in a shared-resource environment and evaluate emerging technologies, models, biomaterials, and applications that may expand the Core's service portfolio.

Essential Function
Yes

Percentage of Time
40

Job Duty

Core Administration and Service ManagementUse Agilent iLab and other institutional systems to review and approve service requests, manage equipment and service access, support scheduling and billing workflows, maintain service documentation, and monitor usage and operational metrics. Assist the IRF Director with service costing, reporting, planning, and other administrative activities related to the division.

Essential Function
Yes

Percentage of Time
15

Position Attributes

Employees in Safety-Sensitive or Security-Sensitive positions will be subject to pre-employment and post-employment drug testing in accordance with University policy HR 1.95 Drug and Alcohol Testing.

Safety Sensitive or Security Sensitive
No

Hazardous weather category
Non-Essential

Posting Detail Information

Number of Vacancies
1

Desired Start Date

Job Open Date
09/25/2026

Job Close Date
10/02/2026

Open Until Filled
No

Special Instructions to Applicant

Please ensure that the cover letter provides details on your experience with 3D cell and tissue culture, cell sorting, and fluorescence cell imaging.

Positions are advertised for a minimum of five (5) business days on our job website. After five (5) business days, positions can be closed at the discretion of the department at any time. This employment site is updated on a regular basis. The length of the recruitment and screening process may vary from position to position, depending upon a variety of factors. Should review of your qualifications result in a decision to pursue your candidacy, you will be contacted by phone or email.

We are only accepting applications submitted by October 2, 2026.

The University of South Carolina offers a valuable benefits package including but not limited to:

• Health and Life Insurance
• Retirement Programs
• Paid Tuition
• Dependent Scholarships
• Annual Leave
• Sick Leave
• 13 Paid Holidays (including an extended December holiday)
• Paid Parental Leave
• Professional Development Opportunities

Quicklink for Posting
https://uscjobs.sc.edu/postings/213711