University of Pittsburgh

OMICS Lead - Lab Manager II

University of Pittsburgh$70K — $95K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 5-7 years of experience in clinical testing and multi-omics lab environments
  • Proficient in molecular biology techniques such as PCR, sequencing, and nucleic acid isolation
  • Strong analytical and problem-solving skills
  • Experience with laboratory information management systems (LIMS)
  • Ability to operate and maintain laboratory equipment and automated instruments

Responsibilities

  • Independently perform clinical tests following established SOPs
  • Accurately log and manage sample data using LIMS and barcode systems
  • Utilize molecular biology techniques for assay preparation and analysis
  • Operate high-throughput automated systems for efficient sample processing
  • Analyze and interpret molecular assay results for clinical staff
  • Train and mentor new lab personnel
  • Assist in research projects and contribute to assay development

Benefits

  • Professional development opportunities including seminars and educational programs
  • State-of-the-art laboratory environment
  • Collaboration with leading researchers and professionals in the field
  • Access to cutting-edge multi-omics technologies
  • Strong focus on quality assurance and compliance in a clinical setting
Full Job Description
The University of Pittsburgh is establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines including genomic sequencing, metagenomics, and RNA sequencing. We are seeking a highly motivated senior technician with experience in these areas and demonstrated team skills. 1. Independently perform clinical testing in accordance with established SOPs. Process all clinical, QC and PT specimens through clinical workflow. 2 Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing. 3 Accurately record relevant data and values in case folders and internal databases. Perform high-volume sample triage, accessioning, and barcoding according to CAP/CLIA and institutional SOPs. Ensure complete and accurate logging of sample receipt, aliquoting, and storage in the LIMS to maintain traceability across all omics workflows. 4 Maintain proficiency in LIMS for comprehensive sample tracking and workflow documentation. Use barcode scanning to monitor progress and link sample metadata to assay results across genomic, proteomic, and metabolomic pipelines. 5 Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc. 6 Independently operate automated and/or liquid handling machines for clinical testing, including high-throughput sample preparation and assay setup. 7 Accurately and precisely analyze molecular assay results for final interpretation by medical staff. 8 Process samples meticulously to avoid cross-contamination. 9 Meet established turn-around-time deadlines for clinical testing. 10 Operate, perform routine maintenance on, and calibrate all laboratory equipment as required. 11 Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols. 12 Identify critical, abnormal and/or unacceptable results and follow-up according to established protocol. 13 Document all corrective action and follow-up with lead and/or supervisor. 14 Effectively communicate with other laboratory members including lab leadership. 15 Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities. 16 Adhere to established laboratory and hospital policies and good clinical laboratory practice in areas of procedures, quality control, quality assurance and safety and compliance. 17 Assist in research projects, new assay development and/or document control review as requested. 18 Train new lab members. 19 Maintain supply inventory and order new supplies when needed. 20 Help with instrument maintenance / PM. 21 Demonstrate excellent organizational skills and time management to process large batches of samples efficiently while maintaining accuracy and compliance under strict turnaround-time requirements. 22 Contribute to cross-platform QA/QC efforts, ensuring harmonization of standards across genomics, proteomics.

About University of Pittsburgh

The University of Pittsburgh is a state-related research university located in Pittsburgh, Pennsylvania. It was founded in 1787 and is one of the oldest continuously chartered institutions of higher education in the United States. The university offers a wide range of undergraduate, graduate, and professional degree programs across 17 schools and colleges. The University of Pittsburgh is known for its strong programs in health sciences, engineering, business, and law. It is also home to a number of research centers and institutes, including the Pitt Innovation Institute and the Center for Energy.
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