Neuroscience PhD (Computational / Active Inference)

Clera

$150K *
Healthcare
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in computational neuroscience, cognitive science, active inference, or a closely related field (strict requirement)
  • Hands-on experience with inference models for emotional or physiological data
  • Strong machine learning engineering skills including model development and deployment
  • Experience with active inference frameworks and methods
  • Comfortable working on-site in San Francisco or London with ability to work without new visa sponsorship

Responsibilities

  • Design and develop the inference model for quantifying emotional states from wearable data
  • Own the entire ML lifecycle from model development to production deployment
  • Apply active inference frameworks to signal processing challenges
  • Collaborate with founding team on science and product roadmap
  • Grow into a leadership role as the company scales

Benefits

  • Equity up to 1-2% as part of the founding team package
  • Flexible working location between San Francisco and London
  • Early involvement in a Y Combinator-backed startup
  • Growth opportunities in a fast-paced environment
Full Job Description
About the Role

This is a founding technical role at a Y Combinator-backed consumer healthtech startup building a wearable that quantifies emotional states in real time. The company is early-stage (team of ~5), already has prototypes on users' wrists, and is growing fast. You'll own the core inference model that powers the product - bridging cutting-edge computational neuroscience with production machine learning engineering.

This is not a pure research role. Computational neuroscientists here effectively double as ML engineers, taking models from research through to deployment.
What You'll Do
  • Design, develop, and iterate on the inference model that quantifies emotional states (e.g. energy, mood, focus) from multimodal wearable sensor data - including audio and biometric signals
  • Own the full ML lifecycle: model development, evaluation, and production deployment
  • Apply active inference frameworks and computational neuroscience methods to real-world signal processing challenges
  • Bridge neuroscience research and production ML, collaborating closely with the founding team to shape both the science and the product roadmap
  • Grow into a leadership role as the company scales
What We're Looking For

Required
  • PhD in computational neuroscience, cognitive science, active inference, or a closely related field - this is a strict requirement
  • Hands-on experience building and deploying inference models to quantify emotional or physiological states from wearable sensor data
  • Strong machine learning engineering skills: model development, evaluation, and deployment
  • Experience with active inference frameworks and computational neuroscience methods
  • Comfort working on-site (San Francisco or London) and ability to work without new visa sponsorship (visa transfers considered for the London office)

Nice to Have
  • Experience working in a fast-moving, early-stage environment
  • Python proficiency across the ML stack
  • Background in consumer health, biometrics, or affective computing

Not a fit: Candidates with a wet-lab-only neuroscience background and no computational or ML engineering experience.
Compensation & Benefits
  • Salary: ~$150,000 USD (San Francisco) / ~£75,000 GBP (London)
  • Equity: Up to 1-2% (founding team equity package)
  • Backed by angels and strategic partners (pre-Series A / seed stage, YC Spring 2026)
Location
  • On-site in San Francisco, CA, USA or London, UK - location is flexible between the two
  • Visa sponsorship: Not available for new sponsorships; visa transfers may be considered for the London office

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