GSK

Molecule Steward Lead - Small Molecules

GSK$200K — $333K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree in chemistry, pharmaceutical sciences, chemical engineering or related field; advanced degree preferred.
  • 8+ years of experience in small molecule development or related area.
  • Proven background in molecule stewardship and product lifecycle management.
  • Experience leading cross-functional technical teams in a matrix structure.
  • Knowledge of global regulatory standards for pharmaceutical development and manufacturing.
  • Ability to manage technical investigations and corrective actions.

Responsibilities

  • Lead end-to-end technical strategy for small molecule assets.
  • Translate scientific data into actionable insights for stakeholders.
  • Ensure regulatory compliance through rigorous data integrity and documentation.
  • Align efforts across various sites and teams for consistent product quality.
  • Manage Product Technical Lifecycle Team activities and risk assessments.
  • Share best practices for analytical stability and product robustness.

Benefits

  • Health care and insurance benefits for employees and family.
  • Retirement benefits including a pension plan.
  • Generous paid time off including holidays and vacations.
  • Paid parental and medical leave.
  • Eligibility for an annual bonus and long-term incentive program.
Full Job Description

Position Summary
You will lead molecule stewardship for small molecule programs across development and manufacturing. You will partner with discovery, process development, analytics, regulatory, manufacturing and external suppliers. We value collaborative leaders who make clear technical decisions, care for quality, and focus on patient impact. This role offers visible influence across program lifecycles, strong growth opportunities, and the chance to help GSK unite science, technology and talent to get ahead of disease together.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Lead technical stewardship for a portfolio of small molecule programs from candidate selection through commercial lifecycle.

  • Define and maintain product control strategies, lifecycle plans and technical deliverables.

  • Coordinate cross-functional teams on technology transfers, process performance qualification, and ongoing process verification.

  • Oversee technical risk assessments and deliver mitigation plans for quality, supply and regulatory readiness.

  • Provide hands-on technical leadership for investigations, troubleshooting and major change programs across sites and suppliers.

  • Mentor and develop the molecule stewardship team and build strong relationships across the network.


Responsibilities

  • Own end-to-end technical strategy and decision points for assigned small molecule assets.

  • Translate scientific and analytical data into clear, actionable guidance for program teams and stakeholders.

  • Ensure data integrity, documentation and evidence support for regulatory submissions and inspections.

  • Drive alignment across sites, contract manufacturers and internal teams to ensure consistent product performance.

  • Lead Product Technical Lifecycle Team activities and yearly robustness reviews to identify and resolve risks.

  • Share best practices for characterization, stability strategies and analytical approaches to improve product robustness.


Why You?
This role is based in the United States and offered as a hybrid role. You will combine on-site collaboration with flexible remote working to meet team and program needs. You will work in a fast-paced, collaborative environment where your technical leadership will shape program outcomes. We welcome people who are accountable, inclusive and focused on delivering quality for patients.

Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals

  • Bachelor’s degree in chemistry, pharmaceutical sciences, chemical engineering or related field. Advanced degree preferred.

  • At least 8 years’ experience in small molecule development, analytical development, process development or related area.

  • Demonstrated experience in molecule stewardship, technology transfer or product lifecycle management for small molecules.

  • Experience leading cross-functional teams and making technical decisions in a matrix environment.

  • Knowledge of global regulatory expectations for pharmaceutical development, manufacturing and quality.

  • Experience managing technical aspects of investigations, deviations and corrective actions.


Preferred Qualification
If you have the following characteristics, it would be a plus

  • Master’s or PhD in a relevant discipline.

  • Direct experience with technology transfer to multiple sites and with contract manufacturing organizations.

  • Experience designing stability programs and analytical characterization strategies for small molecules.

  • Familiarity with risk-based approaches and project management tools.

  • Proven track record developing technical talent and leading diverse teams.

  • Comfortable working across time zones and with cross-cultural, matrixed teams.


Apply now
If this role feels like a fit, please apply and tell us how your experience will help move safe, effective small molecule medicines forward. We look forward to hearing from you.

#LI-GSK

The US annual base salary for new hires in this position ranges from $200,250 to $333,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.French Salary Range / Fourchette salariale – France EUR 0 to EUR 0The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. This role is available for applicants from multiple locations, and therefore salary ranges for certain locations are also shown. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the candidate’s skills, experience, education level and the market rate for the role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria.

Please visit  to learn more about the comprehensive benefits program GSK offers US employees.

About GSK

GSK is a British multinational pharmaceutical company that specializes in researching, developing, and manufacturing a wide range of prescription drugs and vaccines. The company was founded in 2000 through the merger of Glaxo Wellcome and SmithKline Beecham. GSK's products are used to treat a variety of conditions including respiratory diseases, HIV/AIDS, and cancer. The company operates in over 150 countries and has a workforce of over 99,000 employees. GSK is headquartered in Brentford, England and is listed on the London Stock Exchange and the New York Stock Exchange.
Learn more about GSK
Size
90,096 employees
Market Cap
$71.6 billion
Industry
Net Income
$5.7 billion
Founded
1929
5 Year Trend
+4.1%
Revenue
$34 billion
NASDAQ

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