Member of Technical Staff, Rare Disease

LatchBio

$250K — $400K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Years of hands-on experience in rare or inherited disease diagnosis
  • Proven track record in developing therapies or pipelines for rare diseases
  • Strong and defendable opinions on best practices in the field
  • Desire to establish and grow a new function within the company

Responsibilities

  • Author and deliver rare disease benchmarks as per the roadmap
  • Serve as the final reviewer for all rare disease claims at Latch
  • Collaborate on drug programs in the wet lab, influencing discovery workflows
  • Engage with CROs, labs, and patient foundations to inform benchmarks
  • Build a team and establish partnerships to support the function

Benefits

  • Equity and 401(k) contributions to support financial growth
  • Comprehensive Blue Shield Platinum health plan with no out-of-pocket costs
  • Daily meals provided, including both lunch and dinner
  • Travel and accommodation expenses for scientific conferences covered
Full Job Description
Member of Technical Staff, Rare Disease
The role

You will be Latch's authority on inherited disease. You will own our rare disease benchmarks and decide what a correct rare disease workflow looks like, from variant to mechanism to therapeutic strategy, so that every task we ship would satisfy a clinical geneticist.

This is a new function at Latch. You will define what it needs as much as you will execute it.
What you will do
  • Author and ship the rare disease benchmarks on our roadmap: RareDisease-App and RareDiseaseBench-App.
  • Be the scientific authority at Latch for all things rare and inherited disease. Before Latch makes a claim about a rare disease, you are the final reviewer.
  • Potentially collaborate on and run drug programs in the wet lab, guiding discovery and development workflows. We are considering running agent-directed drug programs in a real lab.
  • Work with CROs, diagnostic laboratories, and patient foundations to run experiments and gather data that inform the design of our benchmarks and agents.
  • Build a function beyond yourself: advisors, partners, and a hiring plan.
What we look for
  • You have spent years working hands-on in rare or inherited disease: diagnosing patients, building the pipelines that do, or developing therapies for them.
  • You have strong, defensible opinions about what correct work looks like in your field.
  • You want to build a function, not fill a seat.
The interview

One interview will be a detailed discussion of a rare disease case or program you know well: how the diagnosis was reached, the mechanism behind it, and where the workflow could have gone wrong.
Location

This is a full-time, in-person position at our waterfront office in China Basin, San Francisco. The team works from the office five days a week. The role is not hybrid or remote.
Compensation and benefits
  • Total compensation ranges from $250,000 to $400,000, depending on experience.
  • We believe in long-term incentive plans and provide equity and 401(k) contributions.
  • Benefits include a Blue Shield Platinum health plan with 100% of premiums covered, no deductible, and no out-of-pocket costs.
  • Daily meals, including lunch and dinner, are provided. Travel and accommodations for scientific conferences and other professional networking trips are included.

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