Thermo Fisher Scientific

Manager - US Mainframe Applications

Thermo Fisher Scientific$110K — $130K *
Information Technology
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree plus 8 years of relevant IT experience, or Advanced degree plus 6 years of experience
  • Minimum of 3+ years in a people management or technical leadership role
  • Significant experience working in mainframe application environments
  • Strong working knowledge of IDMS databases, VSAM files, and mainframe application support
  • Demonstrated ability to manage both operational support and project delivery concurrently
  • Proven experience partnering with business stakeholders and leading cross-functional initiatives
  • Strong communication, leadership, and decision-making skills

Responsibilities

  • Lead and develop a team of mainframe application professionals
  • Oversee day-to-day support of production mainframe applications
  • Manage and prioritize enhancement, maintenance, and project work
  • Serve as a primary technology partner to business stakeholders
  • Ensure effective development, testing, deployment, and ongoing maintenance of mainframe applications
  • Support modernization initiatives and technical debt reduction
  • Foster a culture of continuous improvement, operational excellence, and accountability

Benefits

  • Onsite role located in Pittsburgh, PA
  • Opportunities for career development and professional growth
  • Resources provided to achieve individual career goals
  • Opportunity to work on modernization and system transformation initiatives
  • Collaborative work environment with IT architecture, security, and QA teams
Full Job Description
Work Schedule
Standard (Mon-Fri)

Environmental Conditions
Office

Job Description

Manager, Mainframe Applications

Onsite - Pittsburgh, PA
Key Responsibilities
  • Lead and develop a team of mainframe application professionals, including full-time employees and contingent resources
  • Oversee day-to-day support of production mainframe applications, ensuring high availability, performance, and timely issue resolution
  • Manage and prioritize enhancement, maintenance, and project work, including direct management of select application projects
  • Serve as a primary technology partner to business stakeholders, translating business needs into effective technical solutions
  • Ensure effective development, testing, deployment, and ongoing maintenance of mainframe applications
  • Provide leadership and oversight for systems utilizing IDMS databases, VSAM files, and related mainframe technologies
  • Support modernization initiatives, including system enhancements, technical debt reduction, and integration with distributed or cloud-based platforms
  • Collaborate closely with architecture, infrastructure, security, QA, and other IT teams to ensure aligned delivery
  • Manage vendor and contractor relationships, including performance oversight and deliverable management
  • Ensure compliance with internal controls, security standards, and regulatory requirements
  • Contribute to budgeting, forecasting, and resource planning for mainframe applications
  • Foster a culture of continuous improvement, operational excellence, and accountability
Required Qualifications
  • Bachelor's degree plus 8 years of relevant IT experience, or Advanced degree plus 6 years of experience
  • Minimum of 3+ years in a people management or technical leadership role
  • Significant experience working in mainframe application environments
  • Strong working knowledge of IDMS databases, VSAM files, and mainframe application support
  • Demonstrated ability to manage both operational support and project delivery concurrently
  • Proven experience partnering with business stakeholders and leading cross-functional initiatives
  • Strong communication, leadership, and decision-making skills
Preferred Qualifications
  • Experience managing hybrid teams with both employees and contractors
  • Exposure to mainframe modernization or system transformation initiatives
  • Familiarity with SDLC methodologies (Agile, waterfall, or hybrid)
  • Experience working in regulated environments (e.g., GxP, FDA)
  • Industry certifications such as ITIL, PMP, or Agile
  • Experience with enterprise integration and modern IT architectures
  • Travel may be required up to 25%

About Thermo Fisher Scientific

Thermo Fisher Scientific Careers

Join the vibrant team at Thermo Fisher Scientific, a global leader in serving science and making the world healthier, cleaner, and safer. With a workforce of over 75,000 professionals, Thermo Fisher Scientific offers unparalleled job opportunities and a culture of innovation that propels your career to new heights. Work You’ll Do At Thermo Fisher Scientific, you will be part of a team that is dedicated to enabling our customers to make the world healthier. Whether you are involved in the development of life-saving drugs or innovative environmental solutions, your work will have a profound impact on society. Our commitment to leadership in the industry is unwavering. With Thermo Fisher Scientific, you will lead projects that set standards in scientific inquiry and market leadership. You will work at the intersection of science, technology, and industry expertise, driving digital innovation in every aspect of our business. Join our diverse team of professionals and engage in roles that span across various functions and disciplines. From research and development to marketing and sales, the breadth of job opportunities available means that you can find the perfect match for your skills and passions. Innovative Work As part of our team, you will have access to cutting-edge tools and technologies that foster creativity and innovation. Thermo Fisher Scientific is home to a dynamic range of career paths, all designed to challenge you and help you grow as a professional. Our employment philosophy emphasizes diversity and inclusivity, ensuring that all team members have the opportunity to thrive. We believe in nurturing talent through robust training programs, leadership development, and opportunities for career advancement. Be Part of a Great Team Working at Thermo Fisher Scientific means being part of a global network of enthusiastic, talented, and ambitious individuals. Our culture is built on collaboration, where each member’s unique skills and perspectives are valued. You will enjoy benefits that support both your professional growth and personal well-being. Future-Proof Your Career Embark on a journey of growth and continuous learning with Thermo Fisher Scientific. We offer a variety of training and development programs that cater to your interests and career goals. From internships for budding scientists to leadership training for aspiring executives, our programs are designed to equip you with the skills needed for a successful and fulfilling career. Explore Discover how our commitment to innovation leads to advancements in health and science: [Read More] Learn about our leadership in environmental sustainability and how you can contribute: [Read More] The Thermo Fisher Scientific Difference Our global presence and commitment to innovation mean that your work extends beyond borders and makes a tangible impact worldwide. The collaboration between our teams drives our leadership in the scientific community and contributes to a culture that embraces diversity and fosters professional growth. Stay Connected Join Our Team Search open positions that match your skills and interest. We are always on the lookout for passionate, curious, and driven team players. Explore our job opportunities and find out how you can contribute to our meaningful work. SEARCH THERMO FISHER SCIENTIFIC JOBS Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. READ CAREERS BLOG Job Alert Emails Customize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding opportunities that await at Thermo Fisher Scientific.
Learn more about Thermo Fisher Scientific
Size
130,000 employees
Market Cap
$213.3 billion
Industry
Net Income
$6.3 billion
Founded
1956
5 Year Trend
+16.5%
Revenue
$32.2 billion
NASDAQ

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