What You'll Do:

As the Manager, Patient Retention, you will serve as the ultimate operational safeguard for our clinical trial data integrity by actively combating participant dropouts and attrition bias. In this high-impact role, you will monitor early warning systems, tracking eCOA alerts, compliance trends, and site performance metrics in real time. You will act as the vital bridge between Kailera Medical, our CRO partners (IQVIA), and regional CRAs to deploy immediate, tactical interventions for at-risk participants. By turning data insights into rapid clinical action, you will directly protect the statistical power of our landmark GLP-1 pipelines.

Required location: Waltham, MA (hub-based, onsite 3-4 days per week)

Responsibilities:

• Monitor and analyze eCOA data portals, weekly compliance logs, and IRT alerts daily to identify early warning signs of participant non-compliance or potential withdrawal
• Develop and execute proactive, study-wide retention strategies and site-facing communication frameworks to mitigate visit fatigue and protocol discontinuations
• Coordinate joint Kailera/CRO site outreach alongside IQVIA operational leads to provide direct, targeted support to struggling or high-risk clinical sites
• Maintain and optimize the internal clinical trial retention tracker, giving leadership and Medical Monitors (MM) immediate, real-time visibility into active retention risks and resolution
• Design and distribute high-value site tools, patient counseling cheat sheets, and educational resources regarding the non-linear nature of GLP-1 weight loss journeys
• Conduct comprehensive analyses on participant withdrawals to uncover root causes, adjust retention strategies, and clean up historical EDC data

Required Qualifications:

• 6+ years of progressive clinical research experience within biotech, pharma, or a major CRO (e.g., as a CRA, Lead Study Coordinator, or Clinical Operations Project Manager)
• Advanced proficiency working with critical clinical trial technologies, specifically Electronic Data Capture (EDC), IRT, and eCOA dashboard environments
• Proven ability to synthesize complex operational metrics and patient data trends into immediate, actionable risk-mitigation workflows
• Exceptional interpersonal and relationship-management skills, with a track record of successfully navigating high-stakes conversations with PIs, coordinators, and external vendors
• A proven ability to thrive, self-direct, and execute with precision in a fast-paced, fluid, and entrepreneurial startup culture
• Strong emotional intelligence and a solutions-oriented mindset to counsel clinical teams through real-world patient logistics and retention challenges.

Preferred Qualifications:

• Direct operational experience working on Phase 2 or Phase 3 GLP-1, metabolic, or obesity clinical trials
• Prior experience managing complex protocol work alongside large-scale tier-1 CROs

Education:

Bachelor's degree in a life science discipline, healthcare administration, or equivalent practical clinical research experience

Salary Range

$127,000-$155,000 USD

For Full Time Roles: This range represents the company's good-faith estimate of the salary at the time of posting. Actual pay may vary based on experience, skills, qualifications, location, and internal equity. We also offer comprehensive health coverage, flexible time off, paid holidays, and a year-end shutdown. Enjoy a monthly wellness stipend, generous 401(k) match, tuition reimbursement, commuter benefits, disability and life insurance, plus annual bonus opportunities and equity grants-because your well-being and future matter to us.

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