Overview: Centessa Pharmaceuticals, a wholly subsidiary of Eli Lilly and Company is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs.
Description of RoleCentessa is seeking a Manager, Clinical Supply Chain to support end-to-end planning, execution, and maintenance of uninterrupted clinical supply - including investigational product (IP), comparators, and ancillary materials - across assigned clinical programs. This role ensures compliance with GxP requirements, study timelines, and budgets while partnering cross-functionally with Clinical Operations, CMC, Quality, Regulatory, Finance, and external vendors. Reporting to the Senior Director, Clinical Supply Chain, the individual will build strong relationships with internal teams and third-party suppliers to align objectives and support successful trial execution, with particular attention to clinical forecasts, inventory systems, and IRT tools.
Key ResponsibilitiesClinical Supply Planning & Execution- Contribute to the development and execution of clinical supply strategies for early- to mid-phase clinical trials (Phase 1-3 as applicable).
- Manage clinical supply plans, demand forecasts, and inventory strategies - including tracking through Interactive Response Technology (IRT) systems - in alignment with protocol requirements and enrollment projections.
- Support packaging, labeling, distribution, and resupply activities for investigational products and comparators.
- Ensure on-time delivery of clinical supplies to depots and clinical sites globally.
Vendor & CDMO Management- Partner with Quality, Clinical, CMC, and external CDMOs to develop, review, and approve clinical labels, and support CDMO packaging/labeling schedules to ensure supply availability.
- Interact regularly with third-party providers to manage the logistics and licenses required to ship materials from manufacturing to bulk storage facilities, courier depots, and investigator sites.
- Collaborate with CMC and QA to facilitate the document transfer required for IP/QP release by CDMOs.
Quality & Compliance Support- Monitor shelf-life and expiry dating, and coordinate retest/extension activities with the analytical team to ensure continuous supply.
- Manage the investigation, reporting, and communication of outcomes from temperature excursions and product complaints.
- Support product recovery activities pending investigation of IP from investigator sites, as needed.
Cross-Functional Collaboration & Representation- Communicate effectively across functional areas, applying a solid working knowledge of clinical supply chain processes.
- Author Pharmacy Manuals for clinical studies, as needed.
- Represent Supply Chain in Clinical and CMC Sub-Team meetings.
Basic Qualifications- Bachelor's degree in engineering or science required.
- 3-5 years of biotech/pharma industry experience in clinical supply chain, including international experience, required.
- Working knowledge of clinical supply chain processes and GMP/GDP requirements.
- Experience coordinating cross-functional project teams and external vendors.
- Strong organizational, analytical, decision-making, and interpersonal skills, with excellent attention to detail.
- Ability to work independently in a fast-paced, dynamic environment.
- Demonstrated ability to coordinate CDMO activities supporting clinical development of pharmaceutical products.
- Ability to thrive in a small-company culture and contribute to creating and implementing processes.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$66,000 - $169,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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