Manager, LC-MS/MS Bioanalytical

At ICON, we are transforming clinical research by pairing world-class science with a commitment to improving patient lives. As Manager, LC-MS/MS Bioanalytical, you’ll lead a dynamic team advancing bioanalysis for small molecules, biomarkers, peptides, oligonucleotides, siRNAs, and ADCs using cutting-edge LC-MS/MS platforms and automated sample prep workflows.

You’ll have the privilege of contributing to a $9B global organization that brings new therapies to market while enjoying a culture that respects work-life balance, career growth, and scientific excellence.

What You’ll Do

Lead with Scientific and Strategic Vision

• Oversee regulated bioanalysis (GLP/GCLP) method development and ICH validation for a broad range of complex analytes.
• Leverage advanced UHPLC-MS/MS techniques including reverse-phase and SEC chromatography, hybrid workflows, and proteolytic digestion strategies.
• Utilize automated systems (e.g., KingFisher, Hamilton, Integra) and electronic lab notebooks (ELNs) to streamline workflows and ensure data integrity.
• Lead initiatives in modern data processing and visualization using novel quantitation platforms.

Operational & Team Leadership

• Manage lab execution, instrumentation, budgets, and timelines across simultaneous programs.
• Collaborate cross-functionally to align with global ICON strategies and harmonized processes.
• Foster a culture of scientific rigor, operational excellence, and continuous improvement.

Client Engagement & Business Growth

• Serve as the scientific lead for sponsors, delivering proactive communication, strategic guidance, and data interpretation.
• Support proposals and business development efforts by presenting the latest LC-MS/MS research at conferences and meetings.

People Development

• Mentor, coach, and develop scientists and team leads with a focus on accountability, engagement, and personal growth.
• Encourage knowledge sharing, innovation, and collaboration across projects and teams.

What You Bring

• PhD (preferred) or MS in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field.
• 12+ years of bioanalytical industry experience, with 4+ years in a leadership role in a regulated CRO or pharma lab.
• Proven success with UHPLC-MS/MS quantitation for diverse analytes (small molecules, peptides, oligos, ADCs, siRNAs).
• Hands-on knowledge of hybrid workflows, automation systems, ELNs, and LC-MS/MS data processing.
• Strong communication, organizational, and client relationship skills.

Travel:

~10% domestic/international

Apply today and lead the science that drives the future of medicine — with balance, purpose, and global impact.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our to read more about the benefits ICON offers.