The Opportunity:

• We are seeking a Machine Learning Scientist II to help accelerate drug discovery through advanced analytics and artificial intelligence. This hands-on individual contributor will develop and apply predictive models and analytical methods that transform complex biological and chemical datasets into actionable insights for research teams.
• The Machine Learning Scientist II will work at the interface of data science, chemistry, and biology to support target discovery, compound optimization, phenotypic screening, and translational research. The role is well suited to a scientist who brings strong technical foundations in machine learning, curiosity about drug discovery, and a collaborative approach to solving real-world scientific problems.
• Working with senior data scientists and experimental collaborators, the successful candidate will contribute analyses, models, and reusable workflows to a data-driven discovery ecosystem where data, analytics, and experimentation continuously inform one another.
• Develop, implement, and evaluate machine-learning models that support drug discovery questions, including compound activity, selectivity, developability, target engagement, and phenotypic screening outcomes.
• Perform exploratory data analysis and quality assessment on chemical, biological, imaging, and phenotypic datasets.
• Prepare and integrate heterogeneous datasets, including chemical structure and screening data, structural biology outputs, molecular simulation outputs, and high-content imaging or morphological profiling data.
• Apply appropriate modeling approaches, including supervised learning, deep learning, graph-based methods, and ensemble methods, under the guidance of project and functional leads.
• Use sound validation strategies to assess model performance, robustness, applicability, and limitations.
• Collaborate with data engineering and machine-learning engineering partners to support reproducible workflows and integration of analytical outputs into discovery pipelines.
• Partner with medicinal chemists, biologists, and other research scientists to translate scientific questions into computational analyses and communicate results clearly.
• Document methods, code, results, and key assumptions in a manner that supports reproducibility and knowledge sharing.

Required Skills, Experience and Education:

• Ph.D. in machine learning, computational biology, computational chemistry, computer science, statistics, bioinformatics, or a related quantitative field; or a M.S. degree with relevant industry experience.
• Typically 2-5 years of relevant experience applying machine learning, data science, or advanced analytics to scientific datasets; relevant doctoral research may be considered.
• Demonstrated experience developing, validating, and evaluating predictive or classification models.
• Strong Python programming skills and experience with scientific computing libraries such as NumPy, Pandas, and SciPy.
• Hands-on familiarity with machine-learning frameworks such as PyTorch, TensorFlow, and/or scikit-learn.
• Experience with data visualization, exploratory data analysis, and working with noisy or incomplete experimental datasets.
• Ability to communicate technical work clearly and collaborate effectively with cross-functional scientific partners.

Preferred Skills:

• Experience in biotechnology, pharmaceutical, healthcare, or drug discovery environments.
• Experience with phenotypic screening, high-content imaging, Cell Painting, morphological profiling, or computer vision for microscopy images.
• Familiarity with representation learning, self-supervised learning, embedding generation, dimensionality reduction, clustering, or phenotype discovery.
• Familiarity with cheminformatics or molecular modeling tools, such as RDKit or OpenEye.
• Experience with multi-omics data analysis, cloud computing environments, MLOps, or scalable model deployment.
• Working knowledge of cell biology, drug discovery workflows, assay development, microscopy, experimental design, or biological interpretation of machine-learning results.
  #LI-Hybrid #LI-SB1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$182,000-$214,000 USD

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