Lead Ontologist

Black Canyon Consulting

$90K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 5+ years of experience with semantic standards like RDF, RDFS, OWL
  • Strong understanding of SPARQL and query design
  • Familiarity with SHACL, including constraints and semantics
  • Proven experience in designing real-world ontologies
  • Practical knowledge of FAIR Data principles
  • Ability to convert business challenges into structured models
  • Excellent communicator, capable of conveying technical details to non-technical audiences

Responsibilities

  • Execute and shape the ontological approach for the organization
  • Collaborate with stakeholders to clarify and define business use cases
  • Translate use cases into semantic models and schemas
  • Design and build ontologies using LinkML and RDF/OWL
  • Define query patterns and ensure data transformations are aligned with user intents
  • Play a key role in presenting findings to clients and internal teams
  • Participate in design workshops and client interactions, possibly leading sessions

Benefits

  • Remote-first work environment with East Coast hour preference
  • Limited travel (approximately once a month) for key client interactions
  • Opportunity to work with a high-performing, technology-centric team
  • Engagement in a role that bridges technical implementation and business strategy
  • Potential to directly influence semantic modeling practices and approaches
Full Job Description
Overview

We are seeking a Lead Ontologist to execute and help shape this approach. This role sits at the boundary between business understanding and technical implementation. You will work with stakeholders to clarify use cases, define competency questions, and translate those into semantic models, schemas, and query patterns. You will design and build models using LinkML and RDF/OWL, define query skeletons, and ensure that data transformation aligns with the intent of the question. You will also play a visible role in communicating results, both internally and with clients, explaining what the system can answer and why.

This is a remote-first role, with a preference for U.S.-based candidates working East Coast hours. Travel is limited, generally no more than once per month, and focused on design workshops or key client interactions. Depending on experience, you may lead these sessions directly or work alongside senior team members..

Duties & Responsibilities:

Job Responsibilities
  • Strong experience with semantic standards: RDF, RDFS, OWL
  • SPARQL, including query design
  • SHACL, with clear understanding of constraints versus semantics
  • Experience designing and working with ontologies in real-world systems
  • Understanding and practical experience with FAIR (Findable, Accessible, Interoperable, Reusable) Data
  • Demonstrated ability to translate business problems into structured representations, including use cases, questions, and models
  • Strong communication skills, able to explain technical concepts to non-experts and bridge technology and business needs
  • Comfortable working in an iterative, ambiguous environment with evolving requirements
Preferred skills and experience
  • Experience with LinkML
  • Understanding of Labeled Property Graphs (LPG) and OpenCypher
  • Experience with vocabulary standards such as SKOS
  • Experience with data catalog and data product standards, including DCAT and DPROD
  • Background in life sciences or pharma, including translational medicine, clinical data, or real-world data
  • Familiarity with BioLink and other domain models
  • Experience with bioinformatics and biomedical ontology resources
  • Experience with data profiling, reconciliation, and mapping processes
  • Experience with knowledge graph platforms or graph databases
  • Experience in client-facing roles such as workshops, design sessions, and presentations


If you enjoy being part of a high-performing, professional, technology-focused organization, please apply today!

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