AstraZeneca

Lead Automation Engineer - Process

AstraZeneca$108K — $162K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in engineering or a related field, or equivalent practical experience.
  • 5+ years in process automation or operational technology systems within complex environments.
  • Hands-on experience merging robotic systems with third-party manufacturing equipment; AI application is a plus.
  • Demonstrated knowledge throughout the system lifecycle in a GMP-regulated setting.
  • Familiarity with automation architecture and industrial integration standards like OPC and Modbus.
  • Experience with platforms such as Rockwell or Siemens in cell therapy contexts.
  • Strong troubleshooting skills with a balance between urgency and GMP compliance.

Responsibilities

  • Lead the strategy and implementation of a new robotic manufacturing cluster as a key technical authority.
  • Administer critical automation and operational technology platforms, including monitoring systems and the robotics cluster.
  • Address complex automation challenges to ensure secure, reliable, and GMP-validated performance.
  • Guide lifecycle decisions for equipment from concept through replacement.
  • Design and enhance equipment startup logic and operational sequences for manufacturing assets.
  • Utilize AI and system data to improve reliability and real-time process control.
  • Estimate costs to assist in prioritizing strategic investments.
  • Promote energy management automation and continuous improvement in operational performance.

Benefits

  • Eligible for various incentive programs including short-term bonuses and equity awards.
  • Offers qualified retirement plans and paid time off for vacation, holidays, and leaves.
  • Health, dental, and vision coverage in accordance with plan terms.
Full Job Description

The opportunity  - Rockville, MD

Imagine creatingthe intelligentautomation that helps bring advanced cell therapies to patients with greater reliability, speed, and precision. As Senior AutomationEngineer– Cell Therapy, you will be a trustedtechnical leader forhigh-impact projects and daily manufacturing operations across our Cell Therapy network. You will combine automation, operational technology, robotics, data, and GMP expertise to turn pioneering concepts into dependable manufacturing capability.

Your impact

Why thisrolematters

Basedatour Rockville, Maryland site, you will join Facilities and Engineering at a defining moment: the first-of-its-kind implementation of a robotic manufacturing cluster. You will shape the network infrastructure, software and hardware integrations, operating strategy, and lifecycle support that make this platform reliable, compliant, secure, and ready to scale. Leanways of working and standardized methods will help you simplify complexity, improve performance, and focus effort where it creates the greatest value. Because these capabilities support continuous manufacturing operations, the role participatesin a shared 24/7 on-call support model.

What youwill do

  • Lead Automation and Operational TechnologyOTstrategy for the site’s first-of-its-kind robotic manufacturing cluster, serving as the primary technical authority and a trusted partner to Manufacturing, Quality, IT, Engineering, and external suppliers.

  • Own and administer critical Automation/OT platforms, including Environmental and Equipment Monitoring Systems, the Process Orchestration Layer, the robotics cluster, and integrated process equipment.

  • Solve complex automation, OT, and robotics challenges, restore performance quickly, andmaintainsystems in a secure, reliable, and GMP-validated state.

  • Guideequipment lifecycle decisions—from concept, design, and integration through FAT, SAT, commissioning, qualification, validation, maintenance, upgrades, and replacement.

  • Design and continuously improve equipment startup logic, sequences of operation, system architecture, data flows, alarms, notifications, and interfaces for facility and manufacturing assets.

  • LeverageartificialintelligenceAI, system and equipment data toidentifyroot causes, anticipaterisk, improve reliability, and advance real-time process control.

  • Develop sound capital and operating cost estimates that help leaders prioritize strategic investments.

  • Advanceenergy-managementautomation and other continuous-improvementopportunities that strengthen operational and environmental performance.

  • Shareexpertise, mentor colleagues, and help build enduring automation and robotics capability across the organization.

What you bring - Essential Requirements

  • A bachelor’s degree in engineering or a related technical field, or equivalent practical experience.

  • Five or more years of experience implementing and sustainingprocessautomation or OT systems in manufacturing, laboratory,energy-management, or similarly complex environments.

  • Hands-on experience integrating robotic systems with third-party manufacturing equipment; experience applying artificial intelligence to process execution or real-time control is highly valued.

  • Demonstrated capability across the system lifecycle, including ideation, design, implementation, FAT/SAT, commissioning, qualification, validation, and ongoing support in a GMP-regulated environment.

  • Working knowledge of automation architecture, data flows, configuration, alarm management, remote notifications, and industrial integration standards such as OPC, Modbus, BACnet, Ethernet, hardwired interfaces, and parsers.

  • Experience with relevant platforms and equipment such as Rockwell, Siemens, COPA-DATAZenon, process orchestration, historians, electronic batch records, or cell therapy manufacturing systems.

  • Familiarity with system integration, data integrity, and zero-trust cybersecurity principles in a regulated environment.

  • A structured, curious approach to troubleshooting and the judgment to balance operational urgency with GMP requirements.

  • Clear communication and collaborative leadership across multidisciplinary teams and stakeholders.

Additionalexperience that will help you thrive

  • Experience with maintenance-management platforms such as SAP in cell therapy, biotechnology, or pharmaceutical manufacturing.

  • Relevant certifications in process automation, robotics, Rockwell, Siemens, COPA-DATA, industrial networking, cybersecurity, or related disciplines.

Bring your whole perspective

If this opportunity excites you, we encourage you to apply—even if your experience does not align with every preferred qualification. We value people who combine technical depth with curiosity, sound judgment, and a commitment to learning. Join us to build automation that can redefine how cell therapies are manufactured and delivered.

The annual base pay (or hourly rate of compensation) for this position ranges from $108,194.40 - $162,291.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

04-Sep-2026

Closing Date

24-Sep-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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