Merck & Co, Inc

Lead Architect, Data Context Layer

Merck & Co, Inc$142K — $224K *
Enterprise Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a relevant field
  • 8+ years in enterprise architecture or data architecture
  • Strong technical background in data platforms
  • Familiarity with ontologies, OWL, RDF, and knowledge graphs
  • Experience designing self-service, governed access platforms
  • Expertise in agentic AI and context engineering
  • Ability to communicate architecture decisions to diverse stakeholders

Responsibilities

  • Define the target architecture for the data context self-service platform
  • Establish architectural standards for context publishing, discovery, and access control
  • Collaborate with cross-functional teams to align platform design with enterprise needs
  • Evaluate technologies and integration approaches for semantic modeling
  • Design architecture for both self-service user workflows and AI consumption
  • Ensure governance and scalability from development to production
  • Create reference architectures and guide implementation teams

Benefits

  • Medical, dental, and vision healthcare benefits for employee and family
  • Retirement benefits including 401(k)
  • Paid holidays and vacation days
  • Compassionate and sick leave
  • Comprehensive package of benefits as per company policy
Full Job Description

Job Description


Role Overview

This role is part of a broader enterprise initiative to establish a Data Context Layer (DCL) — a foundational capability designed to provide consistent, reusable, and scalable context across enterprise data products.

The DCL is intended to address challenges related to data fragmentation, lack of shared semantics, and inconsistent interpretation of data across systems and products. It establishes a unified layer for representing context, relationships, and meaning, enabling downstream products to operate with greater consistency, interoperability, and intelligence.

In addition, the DCL plays a critical role in enabling agentic AI capabilities across the enterprise by providing the structured context and semantic grounding required for intelligent agents to operate reliably. This includes ensuring that agent-driven workflows and decisions are based on consistent, governed, and interpretable data context, reducing risks associated with fragmentation, ambiguity, and lack of control.

Within this initiative, we are seeking a Lead Architect to define and guide the conceptual and technical architecture for an enterprise platform that enables teams topublish, discover, and consume standardized data context through self-service. This role will shape the target architecture, integration patterns, and technical standards that support scalable, secure, and production-ready context services across the enterprise.

The ideal candidate has deep experience in enterprise architecture, data platforms, semantic technologies, and AI-enabled systems. Familiarity withontologies, OWL, metadata-driven architectures, agentic AI, prompt engineering, and context engineeringis required, as the platform must support both human and AI-driven consumers of context.


Key Responsibilities
  • Define the target architecture for the enterprise data context self-service platform.

  • Establish architectural standards and patterns for:

    • context publishing

    • discovery

    • access control

    • versioning

    • validation

    • lineage and provenance

    • observability and monitoring

  • Partner with product, engineering, service design, security, and governance teams to ensure the platform is technically sound and aligned to enterprise needs.

  • Evaluate and recommend technologies and integration patterns including:

    • ontology and semantic modeling approaches

    • OWL/RDF-based systems

    • knowledge graphs

    • semantic layers

    • MCP, A2A, and Timbr-like technologies where applicable

  • Design architecture that supports both self-service user workflows and AI/agentic consumption patterns.

  • Ensure context can move from development to production in a governed, scalable, and supportable way.

  • Define non-functional requirements including performance, resilience, security, compliance, and operational maintainability.

  • Review solution designs and implementation plans to ensure adherence to architectural standards.

  • Create reference architectures, patterns, and decision records to guide implementation teams.

  • Collaborate with platform teams to support long-term scalability, reuse, and interoperability across domains.

  • Help shape how the platform supportsagentic AI workflows, including structured prompt context, tool access, and reliable data grounding.

Minimum Required Qualifications
  • Bachelors degree

  • 8+ years of experience in enterprise architecture, solution architecture, data architecture, or platform architecture.

  • Strong technical background in data platforms, metadata systems, semantic technologies, or AI infrastructure.

  • Familiarity withontologies, OWL, RDF, knowledge graphs, and semantic layer concepts.

  • Experience designing platforms that support self-service, enterprise-scale reuse, and governed access.

  • Expertise in agentic AI, prompt engineering, and context engineeringconcepts.

  • Experience defining and enforcing technical standards across multiple teams.

  • Strong ability to communicate architecture decisions to both technical and non-technical stakeholders.

Preferred Qualifications
  • Experience with MCP, A2A, Timbr, or similar context-serving or semantic interoperability technologies.

  • Background in enterprise data governance, metadata management, or data catalog architectures.

  • Experience supporting AI-enabled platforms or agentic workflows.

  • Knowledge of production concerns such as observability, testing, CI/CD, identity and access management, and lifecycle management.

  • Experience creating reference architectures and reusable patterns for platform teams.

  • Familiarity with regulated or security-sensitive enterprise environments.

What Success Looks Like

Success in this role means:

  • the platform has a clear, scalable Conceptual/Technical architecture

  • context is served consistently and securely across the enterprise

  • teams can build and integrate using reusable patterns

  • development-to-production flows are reliable and governed

  • the platform supports both enterprise applications and AI/agentic use cases

  • architectural decisions reduce duplication and increase long-term maintainability

Required Skills:

Context Mapping, Data Modeling, Design Applications, Enterprise Architecture (EA), Enterprise Architecture Management, Enterprise Data, Enterprise Data Management, Enterprise Security Operations, Metadata, Metadata Management, Ontology, Prompt Engineering, Reference Architectures, Release Management, Requirements Management, Semantic Web, Solution Architecture, System Designs, System Integration

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

The salary range for this role is

$142,400.00 - $224,100.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los AngelesFair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

07/13/2026

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

Merck & Co, Inc Careers

Join the visionary team at Merck & Co, Inc, a global leader in healthcare dedicated to advancing the world of medicine. As part of our professional community, you'll find dynamic job opportunities that foster innovation and leadership across various fields. Merck & Co, Inc is not just a company; it's a place where you can make a difference.

Work You’ll Do

At Merck & Co, Inc, we are committed to improving global health through groundbreaking research and innovative healthcare solutions. Our team is at the forefront of developing new therapies and vaccines that significantly impact public health worldwide. By joining us, you will collaborate with some of the brightest minds in the industry, using your skills to contribute to projects that save and improve lives around the globe.

Explore Career Paths

Whether you're seeking an internship, a graduate opportunity, or a professional position, Merck & Co, Inc offers a range of career paths in environments that promote rapid professional growth and development. Explore job opportunities in research, digital transformation, manufacturing, and more, all while benefiting from a culture that supports diversity and inclusion.

Innovate and Lead

Merck & Co, Inc is an ideal environment for those who lead with curiosity and the drive to innovate. Our leadership is committed to fostering a culture where inventive thinking and collaboration are encouraged, making it a perfect place for professionals who seek to make an impact through their work.

Develop Your Skills

With Merck & Co, Inc, you are not just getting a job; you're gaining access to unparalleled career development opportunities. Enhance your skills through diverse training programs, workshops, and continuous learning courses designed to help you grow at every stage of your career.

Benefits and Culture

We understand that our employees are our greatest asset, which is why we offer competitive benefits designed to support the health and well-being of you and your family. From comprehensive health care coverage and retirement plans to flexible working conditions and wellness programs, our benefits package is designed to meet the diverse needs of our team members.

Join Our Team

Ready to advance your career at Merck & Co, Inc? Search open positions that match your skills and interests. We are continuously hiring and looking for passionate, creative, and solution-driven team players. Prepare your resume, sharpen your interview skills, and become part of a company that's dedicated to making a difference.

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Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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