Job Title:  Lead AI Engineer

Department:  Digital Transformation – AI Strategy & Execution

Location:  Sleepy Hollow, New York

Employment Type:  Full-Time

Experience Required:  7–10 Years

Regeneron is seeking an experienced Lead AI Engineer to serve as a technical leader within the AI Strategy & Execution organization. In this role, you will architect and deliver enterprise-scale AI capabilities — spanning intelligent agents, LLM-powered applications, and AI platform services — that accelerate drug discovery, clinical research, and enterprise productivity. You will lead a team of engineers, drive cross-functional collaboration, and communicate AI strategy to senior stakeholders, all while maintaining a strong hands-on presence in Python development and AI systems design.

• Lead end-to-end design, development, and deployment of enterprise AI applications and LLM-powered systems, ensuring production-grade quality, security, and scalability.

• Design and build AI Agents and autonomous systems using agentic frameworks including LangChain, LangGraph, Strands, and CrewAI, applying ReAct, tool-use, planning, and memory management patterns.

• Develop and operate MCP (Model Context Protocol) servers for standardized, secure integration between AI agents and enterprise data sources.

• Apply advanced LLM techniques — prompt engineering, fine-tuning, and retrieval-augmented generation (RAG) — to build intelligent, context-aware applications.

• Architect and manage vector database solutions (Milvus DB preferred) supporting semantic search, knowledge retrieval, and RAG pipelines.

• Architect RESTful APIs that expose AI capabilities to internal platforms and downstream business applications.

• Administer and continuously evolve the enterprise LLM and AI Gateway platform, including model routing, access controls, rate limiting, usage observability, and multi-model orchestration.

• Evaluate and onboard new foundation models (OpenAI, Anthropic, AWS Bedrock, and others) in alignment with enterprise security and compliance standards.

• Lead, mentor, and manage a team of AI engineers, conducting code reviews, setting technical standards, and fostering a culture of engineering excellence.

• Contribute to the organization’s AI roadmap through architectural design reviews, technical strategy, and proof-of-concept development.

• Troubleshoot complex issues across AI model serving, APIs, and platform layers.

• Partner with business units, data scientists, and clinical research teams to identify AI opportunities and translate them into scalable technical solutions.

• Serve as the primary technical point of contact for enterprise AI platform discussions, presenting findings and recommendations to senior leadership.

• Engage with external vendors, cloud providers, and AI research organizations to evaluate and integrate emerging capabilities.

• Bachelor’s, Master’s, or Ph.D. in Computer Science, Computer Engineering, Artificial Intelligence or a related technical field.

• 7–10 years of progressive software and AI engineering experience, with at least 3 years in a technical lead or senior individual contributor role.

• Expert-level Python development skills, including production REST API development with FastAPI.

• Proven hands-on experience building AI Agents, MCP Servers, and LLM-powered applications using frameworks such as LangChain, LangGraph, Strands, or CrewAI.

• Hands-on experience with vector databases (Milvus DB preferred) for RAG and semantic search pipelines.

• Experience administering LLM API gateway platforms, including model routing, observability, access governance, and multi-model orchestration.

• Experience with foundation models from OpenAI, Anthropic, AWS Bedrock, and other major providers.

• Working knowledge of AWS cloud services relevant to AI workloads (SageMaker, Bedrock, EKS, Lambda, S3); Kubernetes and CI/CD experience is a plus.

• Experience in the biotechnology, pharmaceutical, or healthcare industry preferred.

• Programming: Python (expert-level).

• AI Frameworks & Runtimes: LangChain, LangGraph, Strands, CrewAI; AWS Bedrock AgentCore.

• LLM Techniques: Prompt engineering, fine-tuning, RAG, vector databases (Milvus DB preferred).

• AI Platform: LLM Gateway management, model routing, multi-model orchestration, TensorFlow, PyTorch.

• API Development: RESTful API design, FastAPI, OpenAPI/Swagger.

• Cloud & Infrastructure (supporting): AWS (SageMaker, Bedrock, EKS, Lambda, S3), Kubernetes, Docker, Terraform, CI/CD pipelines.

• Data & Analytics: Databricks, Dataiku, Postgres, Redis, NoSQL databases.

• Observability: Monitoring, logging, and distributed tracing for AI workloads.

Required:

• AWS Certified Machine Learning – Specialty

Nice to Have:

• AWS Certified Solutions Architect – Professional

• Certified Kubernetes Administrator (CKA)

• Exceptional communication skills with the ability to present AI concepts to both engineering teams and executive stakeholders.

• Proven track record of leading engineering teams and managing delivery across cross-functional groups.

• Strong problem-solving mindset with a bias toward pragmatic, production-ready AI solutions.

• Collaborative and proactive in engaging with business units, compliance, and external partners.

Joining Regeneron as a Lead AI Engineer offers a unique opportunity to shape enterprise AI strategy, build transformative platforms, and make a meaningful impact on the advancement of global healthcare. If you are a driven technical leader with deep expertise in AI systems and a passion for innovation in a regulated environment, we invite you to apply.Please copy and paste the desired job description for this role here. If you need a copy of an existing job description please reach out to TA or work with your HR Business Partner to develop one for a new role.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way!

Salary Range (annually)