Histology Sr. Research Associate Position Summary We are seeking an experienced Histology Scientist to join our Histology team to both support and expand histopathology capabilities for our NAMkind™ Liver and NAMkind™ Intestine platforms. This hands-on role will be responsible for tissue processing, sectioning, staining, imaging, and pathology-support activities that enable drug discovery, toxicology, and disease modeling programs. The successful candidate will initially assume primary responsibility for histology operations and subsequently serve as a key member of the histology team, helping increase throughput and advance tissue characterization capabilities across our 3D human tissue models. Key Responsibilities Histology Operations • Independently process tissue samples from NAMkind™ Liver and NAMkind™ Intestine studies. • Perform fixation, embedding, microtomy, cryosectioning, slide preparation, and tissue preservation. • Maintain high-quality tissue processing workflows with strong attention to reproducibility and turnaround time. • Troubleshoot tissue preparation and staining challenges associated with small, delicate, and 3D tissue models. Histochemical Staining • Execute routine and specialty staining procedures, including: • Hematoxylin and Eosin (H&E) • Picrosirius Red (PSR) • Masson's Trichrome • PAS and related histochemical stains • Additional special stains as required • Optimize and validate staining protocols for novel tissue applications. Immunohistochemistry & Imaging • Perform immunohistochemistry (IHC), immunofluorescence (IF), and related tissue characterization workflows. • Optimize antigen retrieval methods, antibody panels, and staining procedures. • Acquire and manage digital images using microscopy and slide-scanning platforms. • Support image analysis, quantification, and interpretation of histological endpoints. Research & Development Support • Collaborate with scientists investigating liver injury, fibrosis, inflammation, steatosis, intestinal injury, barrier function, and tissue remodeling. • Support development and validation of new histology-based biomarkers and tissue characterization methods. • Contribute to assay development and continuous improvement of tissue-analysis workflows. Quality & Documentation • Maintain detailed laboratory records and SOPs. • Ensure compliance with internal quality standards and laboratory best practices. • Assist with equipment maintenance, reagent inventory, and laboratory organization. Qualifications Required • B.S. or M.S. in Histotechnology, Biology, Pathology, Biomedical Sciences, or a related field. • Minimum 5 years of hands-on histology experience in industry, academia, CRO, or clinical pathology laboratories. • Demonstrated expertise in: • Tissue processing • Paraffin embedding • Microtomy • Histochemical staining • Immunohistochemistry • Strong understanding of tissue morphology and pathology-assisted tissue evaluation. • Ability to independently manage histology workflows with minimal supervision. Preferred • HT(ASCP) or HTL(ASCP) certification. • Experience with liver, gastrointestinal, fibrosis, toxicology, or drug discovery research. • Experience with Picrosirius Red staining and fibrosis quantification. • Experience with immunofluorescence and multiplex staining methodologies. • Experience with organoids, spheroids, microphysiological systems, engineered tissues, or other advanced in vitro models. • Familiarity with digital pathology and image analysis software. Desired Attributes • Exceptional attention to detail and organizational skills. • Strong troubleshooting and problem-solving abilities. • Ability to work independently in a fast-paced biotech environment. • Collaborative mindset and willingness to support cross-functional research programs. • Passion for advancing human-relevant New Approach Methodologies (NAMs) and reducing reliance on animal testing.