AstraZeneca

Facilities Maintenance Supervisor

AstraZeneca$89K — $134K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • High school diploma/GED required; 8+ years in industrial facilities maintenance/leadership experience
  • 4+ years of leadership experience in a pharmaceutical or GMP regulated environment
  • Desirable: Technical diploma/apprenticeship in HVAC or Boiler maintenance
  • Desirable: Bachelor's degree in Mechanical Engineering or Facilities Management is a plus.

Responsibilities

  • Manage and mentor maintenance technicians, setting clear expectations for safety and performance
  • Ensure all maintenance activities comply with GMP, FDA, and site standards
  • Implement reliability-centered maintenance and investigate failures
  • Collaborate with the Maintenance Planner to prioritize and schedule work effectively
  • Enforce safety protocols and conduct audits to maintain a zero-incident culture
  • Remove waste from maintenance processes and lead continuous improvement initiatives
  • Maintain presence on the production floor, supporting cleanroom requirements and off-shift work as needed.

Benefits

  • Qualified retirement program (401(k) plan)
  • Paid vacation, holidays, and paid leaves
  • Health benefits including medical, prescription drug, dental, and vision coverage
Full Job Description
Position Summary:

The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe, compliant, and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana, CA. In a Cell Therapy environment, where products are often patient-specific and time-sensitive, this role is critical to maintaining uninterrupted operations, cleanroom conditions, and strict chain-of-identity and chain-of-custody controls Tarzana, CA. The role integrates reliability engineering principles with daily maintenance execution, focusing on eliminating repeat failures, reducing unplanned downtime, and improving asset lifecycle performance in a highly regulated environment governed by FDA expectations and advanced therapies guidelines.

Success in this role requires the ability to:
• Lead teams in a fast paced, patient-centric manufacturing environment
• Balance speed, compliance, and precision
• Anticipate and mitigate risks to critical, often irreplaceable batches
• Drive transition from reactive to predictive maintenance strategies
• Collaborate multi-functionally with Manufacturing, Quality, and Engineering to support 7 days cell therapy operations

Ultimately, the Maintenance Supervisor plays a direct role in ensuring that life-saving therapies reach patients safely, reliably, and on time, by maintaining the integrity and performance of the systems that produce them.

Responsibilities:
  • Leadership & Team Management: Manage and mentor maintenance technicians; set clear expectations for safety, quality, and performance; lead daily tier meetings and shift handovers; build a culture of ownership, urgency, and continuous improvement; collaborate with Engineering, Quality, and Operations.
  • Maintenance Execution & Compliance: Ensure all activities meet GMP, FDA, and site standards; review and approve complete, accurate work orders; enforce CMMS usage (e.g., SAP); lead aspects of preventive and corrective maintenance and calibrations; maintain inspection readiness and support audits.
  • Reliability & Asset Management: Implement reliability-centered maintenance; investigate failures using RCA and FMEA; improve MTBF and MTTR; identify and resolve "bad actor" equipment; partner on upgrades and lifecycle management.
  • Planning & Scheduling: Work with the Maintenance Planner to prioritize and schedule work; secure parts, tools, and permits in advance; validate and refine job plans; increase labor efficiency and minimize reactive work.
  • Safety, Health, and Environment (SHE): Enforce LOTO, confined space, and permit systems; conduct safety observations, audits, and incident investigations; lead by example to sustain a zero-incident culture.
  • Continuous Improvement: Remove waste from maintenance processes; increase schedule compliance, PM efficiency, and spare-parts management performance; lead or participate in Kaizen and Lean initiatives.
  • Work Environment: AZ is a cGMP regulated pharmaceutical manufacturing facility. We require your presence on the production floor and occasional off-shift support This may involve gowning for cleanroom environments


Minimum requirements:
  • High school diploma/GED required.
    8+ years in industrial facilities maintenance/leadership experience
  • 4+ years of leadership experience in a pharmaceutical, biotech, or GMP regulated environment (medical device/food service may be acceptable.)


Desirable:
  • Technical diploma/apprenticeship in HVAC or Boiler maintenance.
  • Bachelor's degree in Mechanical engineering or Facilities Management is a plus.


The annual base salary for this position ranges from $89,874 to $134,812. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Our Benefits:

Benefits offered include:

  • A qualified retirement program [401(k) plan]
  • Paid vacation, holidays, and paid leaves
  • Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.


#celltherapy

Date Posted
12-Aug-2026

Closing Date
25-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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