Revolution Medicines

Executive Director, Cancer Immunology

Revolution Medicines$265K — $331K *
Pharmaceuticals & Biotech
15+ years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in immunology, cancer biology, or related discipline with a strong research background.
  • 20+ years in biomedical research and oncology drug discovery, preferably in biotech.
  • Proven leadership in portfolio decision-making and program governance in drug development.
  • Strategic thinker with a quantitative and detail-oriented approach to experimental design.
  • Excellent collaboration and communication skills to align diverse stakeholders.

Responsibilities

  • Lead innovative immuno-oncology programs from discovery to development candidate nomination.
  • Define and evolve the long-term scientific strategy for Cancer Immunology research.
  • Ensure operational rigor and scientific integration across Discovery and Translational Cancer Immunology.
  • Foster cross-functional collaboration to advance discovery efforts into clinical development.
  • Mentor and inspire a diverse team of scientists, promoting a culture of excellence.
  • Engage with academic and external partners to enhance the company's scientific reputation.

Benefits

  • Robust equity awards in addition to competitive cash compensation.
  • Comprehensive benefits package including health, dental, and vision coverage.
  • Significant learning and development opportunities for career growth.
  • Flexible work environment with hybrid options.
  • Commitment to diversity and equal opportunity in the workplace.
Full Job Description
The Opportunity:

This role represents a unique opportunity to serve as a senior scientific and strategic leader within Cancer Immunology, with primary responsibility for driving the discovery and advancement of novel immuno-oncology targets and therapeutic modalities. We are seeking an accomplished leader who combines deep scientific expertise with strong people leadership to shape strategy, guide portfolio decisions, and advance high-impact discovery programs.

The successful candidate will lead a multidisciplinary team to progress innovative immuno-oncology programs from early discovery through Development Candidate nomination, while providing senior oversight of scientific integration across Discovery and Translational Cancer Immunology. This role reports to the Vice President and Head of Cancer Immunology and partners closely with Research and Development leadership to support portfolio prioritization and governance. Key aspects of the role include:
  • Discovery Program Leadership & Protfolio Oversight: Provide executive-level leadership of Cancer Immunology discovery programs from project qualification through Development Candidate nomination. Drive the identification and validation of novel immuno-oncology targets, ensuring seamless progression of programs into Translational Cancer Immunology.
  • Scientific Strategy & Platform Leadership: Define and evolve the scientific vision and long-term strategy for Cancer Immunology discovery. Provide senior oversight of the development and optimization of experimental platforms, including in vitro and in vivo models, phenotypic screening, and advanced assay toolkits. Champion the exploration and implementation of new therapeutic modalities, such as TCEs, ADCs, and bispecifics.
  • Scientific Integration & Operational Excellence: Provide senior oversight of scientific integration across Discovery and Translational Cancer Immunology, ensuring operational rigor, platform support, and alignment of resources. Leverage enabling functions and data-driven insights to enhance experimental design, reproducibility, and program execution. Promote the development and deployment of modern data systems and analytics to advance scientific and operational excellence, enabling the establishment of a digitally empowered Cancer Immunology team within the broader organization.
  • Cross-functional Collaboration: Act as a key partner to Research Leadership to support advancement of programs from early discovery into the clinical development portfolio. Foster collaboration across multidisciplinary teams to ensure that discovery efforts, platform capabilities including data platforms, and translational priorities are coordinated and integrated.
  • Team Leadership & Mentorship: Lead, mentor, and inspire a multidisciplinary team of PhD and non-PhD scientists. Cultivate a culture of scientific excellence, innovation, and collaboration.
  • External Engagement: Spearhead collaborations with academic partners and external organizations. Partner with key stakeholders to define publication strategies and support advancement of the company's scientific reputation in the field.

Required Skills, Experience, and Education:
  • Education & Scientific Expertise: Ph.D. in immunology, cancer biology, or a related discipline, with deep expertise in tumor immunology, immune-evasive oncogenic signaling pathways, and/or immunotherapy. Demonstrated track record of excellence in research, evidenced by high-impact publications.
  • Industry Experience: 20+ years of post-PhD experience in biomedical research and oncology drug discovery, including substantial experience in biotech or pharmaceutical settings. Demonstrated leadership in oncology drug discovery and development, including experience with antibody-directed therapies such as T cell engagers, ADCs, or bispecific antibodies, is required. Experience setting early discovery strategy is highly desirable.
  • Senior Leadership & Organizational Impact: Proven ability to lead complex, multidisciplinary organizations and influence across functions and levels. Demonstrated experience in portfolio decision-making, program governance, and developing scientific leaders.
  • Strategic & Analytical Thinking: Enterprise-level strategic thinker capable of prioritizing initiatives, anticipating challenges, and executing effectively in a dynamic, high-energy environment. Rigorous, quantitative, and detail-oriented experimentalist.
  • Collaboration & Communication: Thrives in a collaborative, interdisciplinary team setting. Excellent written and verbal communication skills, with the ability to influence and align diverse stakeholders.

Preferred Skills:
  • Experience with chemistry-based therapies, including small molecules or ADC payloads.
  • Familiarity with bioinformatics-driven discovery and integrating computational insights into experimental design.
  • Demonstrated proficiency with modern data platforms, machine learning approaches, and advanced analytics to support Cancer Immunology research and decision-making.
  • Prior experience as a Program Team Leader, with a track record of driving cross-functional strategy and execution across discovery and development stages.

#LI-Hybrid #LI-LN1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$265,000-$331,000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.

Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.

If you believe you've been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

About Revolution Medicines

Revolution Medicines is a clinical-stage precision oncology company focused on developing targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on RAS and mTOR signaling pathways. The company's proprietary platform enables the discovery and development of small molecules that bind covalently to proteins. Revolution Medicines was founded in 2014 and is headquartered in South San Francisco, California.
Learn more about Revolution Medicines
Size
201 employees
Market Cap
$2.1 billion
Industry
Net Income
-$108.1 million
Revenue
$42.9 million
NASDAQ

Similar Jobs

More Jobs at Revolution Medicines

More Pharmaceuticals & Biotech Jobs

Find similar Executive Director, Cancer Immunology jobs: