Drug Substance Tech Transfer Lead

Help turn molecules into medicines by leading robust technology transfers across a diverse biologics portfolio.

The opportunity

As Drug Substance Tech Transfer Lead, you will lead drug substance technology transfer activities across the biologics portfolio. You will support Global CMC deliverables and enable robust, reliable commercial manufacturing across internal and external networks.

Your primary focus will be post-approval drug substance technology transfers, including antibody-drug conjugates (ADCs). You will also support new product introduction (NPI) transfers, bringing an Operations perspective to scale-up, transfer readiness and long-term manufacturability.

What you will do

• Lead post-approval drug substance technology transfers across internal and external manufacturing sites, ensuring strong planning, execution, risk management and handover to commercial operations.
• Deliver against Global CMC requirements and represent Operations needs in transfer strategies, technical discussions and execution plans.
• Support NPI technology transfers, helping ensure processes are scalable, transferable and suitable for reliable commercial manufacturing.
• Apply working knowledge of upstream, downstream and conjugation operations to transfer strategy, technical assessments, issue resolution and implementation across diverse biologic modalities.
• Assess site capabilities for process transfer, scale-up and lifecycle changes, considering technical fit, equipment capability, facility readiness, capacity and compliance requirements.
• Partner with Manufacturing, MS&T, Quality, Regulatory, Supply Chain, Engineering and external partners to deliver plans aligned with business and supply priorities.
• Embed GMP, quality, inspection-readiness and technical-documentation expectations throughout transfer activities.
• Lead the identification, mitigation and resolution of process, equipment, site, compliance and supply risks.
• Drive standardisation, simplification and continuous improvement across the technology transfer network.
• Help reimagine ways of working through digital technology transfer tools that improve visibility, knowledge transfer, data quality, governance and execution efficiency.
• Influence decisions and build alignment across a complex matrix, including teams and stakeholders outside your direct reporting line.

What you will bring

You are a technically credible, operationally minded leader with experience in biologics drug substance manufacturing and CMC. You can connect technical detail with the practical realities of site readiness, transfer execution and lifecycle management, while building alignment across internal and external networks.

• Significant experience in CMC, drug substance manufacturing, MS&T or a related biologics technical operations role.
• Working knowledge of upstream, downstream and conjugation processes, with sufficient technology transfer understanding to support strategy, execution and issue resolution. Direct technology transfer experience is an advantage.
• Experience supporting biologics portfolios with diverse modalities and understanding the technical and operational considerations involved in transfer and commercialisation.
• Experience leading or supporting post-approval drug substance transfers, ideally including ADCs.
• Experience supporting NPI transfers and contributing a strong Operations perspective to commercial manufacturing readiness.
• Strong understanding of internal and external manufacturing capabilities, including technical fit, site readiness, operational maturity and transfer risk.
• Good understanding of GMP operations, quality systems and regulatory expectations relevant to biologics drug substance manufacturing and transfer.
• Demonstrated ability to influence in a matrix organisation and deliver through collaboration across functions, sites and external partners.
• Strong leadership, communication, problem-solving, risk-management and execution skills in complex technical environments.
• The ability to challenge current approaches and an interest in, or experience with, digital technology transfer.

Education and experience

• Bachelor's, Master's or PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, Biology, Pharmaceutical Sciences or a related discipline.
• 8+ years of relevant experience in CMC matrix leadership, drug substance manufacturing, technology transfer, biologics process development, MS&T or a related pharmaceutical or biologics operations role.

Leadership in this role

You will operate as a trusted technical and operational leader who can translate Global CMC requirements into effective transfer strategies and executable plans. Success will require sound judgment, resilience and the ability to balance technical, quality, supply and business priorities.

You will be expected to represent Operations effectively, build alignment across a broad matrix, lead high-quality transfer execution and continuously improve how drug substance technology transfer is delivered.

Ready to make an impact?

Apply now and help shape the future of drug substance technology transfer in Operations.

The annual base pay for this position ranges from $138,392.80 to $207,589.20. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted
14-sept-2026

Closing Date
04-oct-2026