AstraZeneca

Director, US and Global Forecasting and Analytics - Infectious Disease

AstraZeneca$150K — $180K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a quantitative or business-related field like Statistics or Economics.
  • 4+ years' experience in US and global pharmaceutical commercial forecasting.
  • Expertise in scenario-based forecasting and sensitivity analysis.
  • Strong capability in integrating multiple data types into decision-grade forecasts.
  • Demonstrated forecast governance, including documentation and traceable assumptions.
  • Strong understanding of US market access and payer dynamics.
  • Ability to translate complex analysis into clear, executive-ready insights.

Responsibilities

  • Lead US and global demand forecasts for Infectious Disease assets.
  • Own forecast methodology ensuring objectivity and transparency.
  • Integrate market research and real-world data into forecast models.
  • Identify and quantify key risks and opportunities through analysis.
  • Partner with stakeholders to align on assumptions and implications.
  • Support business planning with executive-ready narratives.
  • Serve as a trusted advisor to senior leadership on forecast drivers.

Benefits

  • Hybrid work model with an average of three days in the office.
  • Opportunity to work on life-changing medicines in the Infectious Disease area.
  • Collaboration with cross-functional teams for innovative solutions.
  • Access to cutting-edge analytics tools and resources.
  • Focus on embedding AI and automation into forecasting practices.
Full Job Description
Director, US and Global Forecasting and Analytics - Infectious Disease (ID)
Wilmington, DE
Global Insights, Analytics & Forecasting, BBU
Hybrid Work - on average 3 days a week from office


The Director is a senior commercial insights leader responsible for US and global demand forecasting and analytics across the Infectious Disease portfolio. The role is predominantly forecast-focused, serving as the US and global forecasting lead and strategic thought partner to Marketing, Finance, Market Access, and US teams. The position also includes vendor management and forecasting-adjacent analytics leadership to ensure the effective deployment of analytical resources and continuous evolution of forecasting and insight capabilities within ID. Time allocation may vary by business cycle and portfolio priorities.

You'll play a critical role in shaping commercial expectations, risk and opportunity framing, and executive decision-making for in-market and late-stage pipeline infectious disease assets.

What you'll do

US and Global Forecasting Leadership (Core Accountability)
  • Lead US and global short-term and long-term demand forecasts (TRx, NBRx, volume, patients, revenue) for ID assets using robust, patient-based and market-based models.
  • Own forecast methodology, assumptions, and governance, ensuring objectivity, transparency, and consistency with enterprise standards.
  • Integrate primary market research, epidemiology, competitive intelligence, access dynamics, and real-world data into forecast models.
  • Proactively identify and quantify key risks and opportunities through scenario and sensitivity analyses.
  • Partner closely with Finance, Market Access & Pricing, Marketing, Sales, Medical, and Global Forecasting to ensure alignment on assumptions and implications.
  • Support business planning, governance reviews, and opportunity assessments with clear, executive-ready narratives.
  • Serve as a trusted advisor to senior marketing and finance leadership, clearly articulating forecast drivers and changes.


Analytics & Resource Leadership (Enablement)
  • Provide leadership over forecasting-adjacent analytics, ensuring analytics and insights are embedded into forecasting and business planning.
  • Manage and prioritize internal analysts, contractors, and external vendors supporting forecasting and analytics deliverables.
  • Partner with data analytics resources, Global IA&F, and GIBEX capability teams to deploy new tools, data sources, and modeling approaches.
  • Champion and identify new ways to embed AI and automation into the practice of data analytics and forecasting to drive efficiency, scalability, and decision quality.
  • Champion continuous improvement in forecasting processes, AI-enabled modeling, and automation.
  • Contribute to the development and sharing of best practices across the ID forecasting community.


Essential for the role
  • Bachelor's degree in a quantitative, scientific, or business-related field, such as Statistics, Economics, Mathematics, Engineering, or Computer/Data Science.
  • 4+ years' experience in US and global pharmaceutical commercial forecasting, including in-market and late-stage pipeline assets.
  • Hands-on model ownership experience, including build, refresh, and performance tracking across short- and long-term horizons.
  • Expertise in scenario-based forecasting, sensitivity analysis, and driver-based narratives to support senior decision-making.
  • Strong capability integrating multiple data types, such as IQVIA, claims, epidemiology, RWD/RWE, and primary research, into coherent, decision-grade forecasts.
  • Demonstrated forecast governance and model risk discipline, including traceable assumptions, documentation, and clear explanations.
  • Strong understanding of US market access and payer dynamics and how they impact demand, including coverage, contracting, channel, and policy.
  • Ability to translate complex analysis into clear, executive-ready insights, options, and recommendations.
  • Strong commercial competence across key demand levers, including positioning, adoption, competitive dynamics, and lifecycle events.


Desirable for the role
  • Advanced degree, such as MBA, MS, or PhD in Statistics, Economics, Decision Sciences, Data Science, or a related field.
  • Infectious Disease and/or Rare Disease experience, including familiarity with immunization dynamics, patient-based forecasting, and lifecycle management in preventive or infectious disease therapies.
  • Change leadership: builds adoption for new tools, processes, and ways of working across cross-functional stakeholders.
  • Product perspective for forecasting: defines user needs, success metrics, and a roadmap for portfolio forecasting capabilities.


Office Working Requirements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

#LI-Hybrid

Date Posted
14-Aug-2026

Closing Date
27-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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