Viridian Therapeutics

Director, Manufacturing Supply Chain Operations

Viridian Therapeutics$150K — $180K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • 12+ years in biotechnology or pharmaceuticals, especially in manufacturing and supply chain
  • Bachelor's in Supply Chain Management, Life Sciences, Pharmacy, Engineering, or similar
  • Experience at a Director level in strategic planning and execution
  • Deep understanding of Supply Chain, External Manufacturing, CMC, Quality, and Regulatory interactions
  • Strong problem-solving skills with a focus on risk mitigation
  • Proven ability to influence and negotiate complex issues in matrixed environments
  • Familiarity with contract management and budgeting processes
  • Combination drug-device experience preferred
  • Excellent communication skills, capable of operating autonomously
  • Willingness to travel domestically and internationally as required

Responsibilities

  • Provide matrix leadership to influence stakeholders and align decision-making
  • Lead contract planning and lifecycle management for Technical Operations
  • Collaborate with Legal and Finance to ensure contracts meet business needs
  • Build relationships with partners for effective negotiation and issue resolution
  • Manage budget processes including forecasting, invoice review, and variance analysis
  • Organize governance meetings to track actions and risks effectively
  • Coordinate vendor selection and onboarding processes
  • Identify improvements for vendor value and operational efficiency

Benefits

  • Competitive pay and stock options
  • Medical, dental, and vision insurance
  • 100% Paid Parental Leave
  • Short- and long-term disability coverage
  • Life, Travel, and AD&D insurance
  • 401(k) Company Match with immediate vesting
  • Employee Stock Purchase plan
  • Generous vacation and holiday shutdowns
  • Comprehensive health programs including fertility and mental health services
Full Job Description
Description

Reporting to the Vice President, External Manufacturing & Supply Chain, the Director, Manufacturing & Supply Operations will lead business operations activities that support Technical Operations, including contract negotiation and lifecycle management, budget planning and roll-up, and business reviews. Operating with significant autonomy, this individual contributor role will impact through matrix leadership, vendor and stakeholder influence, and ownership of business processes that support program, financial, and operational decision-making across Technical Operations.

This role is based in our Waltham, MA headquarters. Our office-based employees are required to work in the office three (3) days a week.

Responsibilities (including, but not limited to):
  • Provide matrix leadership by influencing internal stakeholders, external vendors, and cross-functional partners to align operational decision-making by translating program priorities, business planning, financial assumptions, risk trade-offs, and decision-making inputs without direct people management authority.
  • Lead contract planning, negotiation support, execution, and lifecycle management for Technical Operations
  • Partner with Legal, Finance, and functional stakeholders to ensure contracts include appropriate business terms, deliverables, governance expectations, performance metrics, budget assumptions, and compliance requirements
  • Build productive relationships with external partners and internal stakeholders to support effective negotiation, clear accountability, timely execution, and practical resolution of business and operational issues
  • Contribute to Technical Operations budget management processes, including annual planning inputs, forecast updates, purchase order oversight, invoice review, accrual support, variance analysis, and consolidated budget roll-ups for leadership review
  • Orchestrate governance meetings and business reviews, ensuring clear agendas, decision logs, action tracking, risk escalation, and follow-through on commitments across internal and external stakeholders
  • Support vendor selection, onboarding, and transition activities by coordinating business requirements, operational assumptions, proposal comparisons, contracting needs, budget impacts, governance expectations, and stakeholder decision-making inputs
  • Identify opportunities to improve vendor value, operating efficiency, cost management, contract structure, governance discipline, and cross-functional ways of working across the Technical Operations supplier network


Requirements

  • Requires 12+ years of progressive biotechnology or pharmaceutical experience, including substantial experience manufacturing and supply chain, and related GMP operations
  • Bachelor's degree in Supply Chain Management, Life Sciences, Pharmacy, Engineering, or a related discipline required
  • Demonstrated Director-level ability to participate with senior management in establishing strategic plans and objectives, translate functional strategy into operational plans, and ensure effective execution across internal teams and external partners
  • Mastery of the core functional area with strong understanding of how Supply Chain, External Manufacturing, CMC, Quality, and Regulatory intersect to support company goals and competitive positioning
  • Proven ability to resolve complex, cross-functional operational issues where problems are not clearly defined; anticipates risks, develops practical mitigation plans, and drives measurable outcomes
  • Demonstrated success leading through influence in matrixed environments, including aligning senior stakeholders, reconciling multiple perspectives, and negotiating matters of significance with vendors, partners, or major customers without reliance on direct reporting authority
  • Demonstrated knowledge of contract management, budgeting processes, supplier governance, business reviews, KPIs, and issue escalation
  • Combination drug-device experience desirable
  • Strong written, verbal, and executive-level communication skills; able to operate with significant autonomy, sound judgment, and high accountability in a fast-paced matrix environment
  • Ability to travel domestically and internationally, as needed
  • The salary range for this position is commensurate with experience


Viridian offers a comprehensive benefits package including:

  • Competitive pay and stock options for all employees
  • Medical, dental, and vision insurance
  • 100% Paid Parental Leave
  • Short- and long-term disability coverage
  • Life, Travel and AD&D
  • 401(k) Company Match with immediate company vest
  • Employee Stock Purchase plan
  • Generous vacation plan and paid company holiday shutdowns
  • Various fertility, mental, financial, and proactive physical health programs


About Viridian Therapeutics

Viridian Therapeutics is a biotechnology company that develops gene therapies for inherited diseases. The company's lead product candidate, VRDN-001, is a gene therapy for Friedreich's ataxia, a rare genetic disease that causes progressive damage to the nervous system. Viridian Therapeutics was founded in 2018 and is headquartered in Cambridge, Massachusetts.
Learn more about Viridian Therapeutics
Size
10 employees
Market Cap
$1.1 billion
Industry
Net Income
-$30 million
5 Year Trend
-3.1%
Revenue
$1.8 million
NASDAQ

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