Natera

Director, Head of Product Management - AI-Enabled Precision Medicine (Therapeutics & Innovations)

Natera$184K — $230K *
US-AnywhereRemote in United States
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.
  • 8-12+ years of experience in product management in biotech, life sciences, or healthcare technology.
  • Proven track record of building and launching complex, data-driven products.
  • Strong understanding of drug development workflows and clinical diagnostics.
  • Experience with AI/ML-driven products or data platforms preferred.
  • Ability to translate complex science into clear product decisions and strategies.
  • Demonstrated success leading cross-functional teams in ambiguous environments.

Responsibilities

  • Define and own the product vision and roadmap for AI-enabled tools in precision medicine.
  • Lead the end-to-end product lifecycle from concept to iteration.
  • Engage with biopharma partners to understand needs and workflows.
  • Synthesize customer insights into product requirements.
  • Align stakeholders around a unified product strategy and execution plan.
  • Partner with commercial teams to define product positioning and pricing.
  • Ensure products meet scientific and regulatory expectations.

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Full Job Description
Director, Head of Product Management - AI-Enabled Precision Medicine (Therapeutics & Innovations)

The Role

We are seeking a Director / Head of Product Management to lead product strategy and execution for our AI-enabled therapeutics platform. This is a highly cross-functional leadership role at the center of science, engineering, clinical development, and commercial strategy.

You will define what we build, why it matters, and how it creates value-for biopharma partners, clinicians, and ultimately patients. You will own the product lifecycle end-to-end: from concept and validation through development, launch, and iteration.

This role requires a rare blend of scientific fluency, product rigor, and commercial instinct. You will work closely with R&D, AI, medical, business development, and marketing to ensure our products are scientifically credible, operationally feasible, and commercially compelling.
What You'll Do
Product Strategy & Vision
  • Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings (e.g., biomarkers, trial enablement tools, co-development platforms) via genomic language models, biomedical AI agents, AI-driven analysis platforms, forecasting algorithms.
  • Identify high-value use cases across drug development (e.g., trial design, patient selection, translational insights, companion diagnostics).
  • Translate platform capabilities into clear product strategies aligned with business goals.
Product Development & Execution
  • Lead the end-to-end product lifecycle: concept 1 validation 1 build 1 launch 1 iteration.
  • Partner with R&D, data science, and engineering to define product requirements and ensure high-quality execution.
  • Drive prioritization decisions across competing opportunities based on impact, feasibility, and strategic alignment.
Customer & Market Insight
  • Engage with biopharma partners, clinicians, and internal stakeholders to deeply understand needs and workflows.
  • Synthesize customer insights into product requirements and roadmap decisions.
  • Continuously assess market trends, competitive landscape, and emerging technologies.
Cross-Functional Leadership
  • Serve as the central hub across Product, R&D, Clinical, BD, and Marketing.
  • Align stakeholders around a unified product strategy and execution plan.
  • Drive decision-making in a matrixed, fast-moving environment.
Commercialization & Launch
  • Partner with commercial and BD teams to define product positioning, packaging, and pricing.
  • Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments.
  • Ensure successful product launches with clear value propositions and supporting evidence.
Data, Evidence & Validation
  • Define requirements for product validation, including analytical, clinical, and real-world evidence.
  • Ensure products meet scientific, regulatory, and commercial expectations.
  • Partner with clinical and regulatory teams to align product strategy with approval pathways where applicable.
Team Building & Leadership
  • Build and mentor a high-performing product management function.
  • Establish product processes, operating cadence, and best practices.
  • Foster a culture of ownership, speed, and scientific rigor.


What We're Looking For
  • Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.
  • 8-12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology.
  • Proven track record of building and launching complex, data-driven products.
  • Strong understanding of drug development workflows and/or clinical diagnostics.
  • Experience working with AI/ML-driven products or data platforms is highly preferred.
  • Exceptional ability to translate complex science into clear product decisions and strategies.
  • Demonstrated success leading cross-functional teams in ambiguous environments.
  • Strong commercial acumen, including product-market fit, pricing, and partnership models.

Bonus:
  • Experience with biomarker development, oncology, or precision medicine.
  • Background in diagnostics + therapeutics integration.
  • Experience in early-stage or high-growth environments.
Why Join Us
  • Build and define an entirely new category at the intersection of AI, diagnostics, and therapeutics.
  • Own product strategy for some of the most advanced datasets and capabilities in healthcare.
  • Work alongside world-class scientists, clinicians, and business leaders.
  • Directly impact how therapies are developed and delivered to patients.


The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$184,600-$230,700 USD

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits


Compensation Range

$184,600-$230,700 USD

About Natera

Natera is a biotechnology company that focuses on genetic testing and diagnostics. The company's products are designed to help diagnose and treat genetic diseases, cancer, and other conditions. Natera's pipeline includes products for reproductive health, oncology, and organ transplantation. The company was founded in 2003 and is headquartered in San Carlos, California.
Learn more about Natera
Size
2,670 employees
Market Cap
$4.5 billion
Industry
Net Income
-$229.7 million
Founded
2004
5 Year Trend
+24.1%
Revenue
$391 million
NASDAQ

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