As we approach our next phase of growth, we are seeking a Director, Finance to serve as the senior finance business partner for our cGMP manufacturing operations facility. You will partner directly with site leadership - including Manufacturing, Supply Chain, Engineering & Facilities, Process Sciences, Analytical Sciences, Quality, and People & Culture - to drive budgeting, cost management, capital planning and long-range financial strategy for CMC Operations. This is a highly visible, cross-functional leadership position ideal for a finance professional who is comfortable navigating the economics of gene therapy and who thrives operating as an embedded strategic partner rather than a back-office analyst. This role is based in Morrisville, NC and reports to the Vice President, Finance. Responsibilities - Site Finance Partnership: Serve as the primary finance point of contact and trusted advisor for CMC site leadership, providing financial insight that informs day-to-day operating decisions and long-term site strategy - Budgeting & Forecasting: Lead the annual budgeting and periodic forecasting process for the manufacturing site functions, including headcount, operating expenses, capital expenditures and cost of goods - Manufacturing Cost Accounting: Own batch costing, standard costing and variance analysis for GMP drug substance/drug product manufacturing, identifying and explaining drivers of cost variance to plan - Capital Planning: Develop business cases and ROI analyses for capital projects (e.g., new suites, equipment, automation), as needed - Inventory & Supply Chain Finance: Partner with Supply Chain and Manufacturing on raw material, consumable and inventory planning; support inventory valuation, cycle counts and other analyses - Reporting & KPIs: Design and deliver recurring financial and operational KPI dashboards for site leadership, translating complex manufacturing and financial data into meaningful insights - Controls & Compliance: Ensure site financial processes and controls comply with SOX, internal policy, and GxP-adjacent documentation standards; support internal and external audits as the site finance representative - Workforce Planning: Lead or contribute to headcount planning, org design discussions, and workforce cost modeling in partnership with Site Leadership and HR Business Partners Requirements - Education: Bachelor's Degree in Finance, Accounting, Economics or a related field - Experience: 12+ years of progressive finance/accounting experience, 5+ years supporting a manufacturing plant or site operation - Industry Expertise: Proven experience in the Biotech/Life Science industry - Technical Proficiency: Demonstrated experience with manufacturing cost accounting, including standard costing, batch/product costing, and COGS/COGM analysis. Working knowledge of CMC and GMP manufacturing operations; direct exposure to cell therapy, gene therapy, biologics, or other advanced-therapy manufacturing is a strong plus. - Systems and Tools: Proficiency with Coupa and Adaptive preferred - Communication: Strong verbal and written communication skills; comfortable presenting financial analyses to senior leadership and cross-functional stakeholders. - Leadership: Demonstrated leadership capability, including managing cross-functional stakeholders - Business Partnership: Proven ability to partner with non-finance operational leaders (Manufacturing, Quality, Engineering, Supply Chain) and translate financial concepts into operational terms, and vice versa Benefits - Comprehensive benefits package, including competitive employer premium contributions - Meaningful stock option grants - PTO, sick time, and holiday pay - Generous Parental Leave program - Pre-tax medical and dependent care programs - STD, LTD, Life and AD&D - Professional development opportunities - Team-building events - Stocked micro-kitchen with drinks and snacks - Wellness Resources