Merck & Co, Inc

Director, Discovery Chemistry

Merck & Co, Inc$194K — $305K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's with 13+ years, Master's with 9+ years, or Ph.D. with 7+ years in chemistry or related field
  • Experience in bioconjugate chemistry, linker and payload design
  • Proven track record of leading drug discovery projects
  • Strong communication and collaboration skills
  • Ability to influence strategy across organizational boundaries

Responsibilities

  • Lead and develop a team of exceptional scientists
  • Drive high-impact drug-conjugate projects across therapeutic areas
  • Shape and influence scientific strategy with industry knowledge
  • Foster collaborations with internal and external stakeholders
  • Promote a culture of scientific excellence, accountability, and innovation

Benefits

  • Medical, dental, and vision healthcare for employee and family
  • 401(k) retirement benefits
  • Paid holidays, vacation, and compassionate/sick days
  • Opportunities for annual bonus and long-term incentives
  • Commitment to inclusion and accommodations during hiring process
Full Job Description
Job Description

Our Discovery Chemistry team in South San Francisco, CA is looking for a collaborative and creative Director to join us. In this role, you will have the opportunity to develop people, lead transformative projects, influence scientific strategy, set departmental vision, and expand your network. As a leader in our organization, you will leverage your talent across the following principal responsibilities:

Leverage your people leadership talent to enable the growth and development of a team of exceptional scientists. This includes fostering their scientific curiosity, guiding their career paths, and promoting continuous learning. By embracing a culture and modeling inclusive behaviors, you will create an environment where everyone feels valued and supported.

Lead Drug Discovery Projects: Utilize your expertise in bioconjugate drug discovery to lead high-impact research drug-conjugates projects across multiple therapeutic areas. Collaborate with cross-functional, multidisciplinary teams, leveraging their skills and knowledge, to achieve project goals and milestones. Your strategic thinking, innovative problem-solving, and incisive decision-making will drive outcomes that can transform the lives of patients.

Contribute to Scientific Strategy: Shape our scientific strategy by applying your deep knowledge of bioconjugate chemistry, staying informed on and sharing industry trends. Collaborate with key stakeholders to identify promising biological targets, innovative technologies, and cutting-edge research approaches. Provide strategic guidance and data-driven recommendations that align with our mission and goals, driving scientific innovation and enhancing our competitive position.

Influence the internal and external scientific community: Leverage your strong network and effective communication skills to foster collaborations with partners, thought leaders, and stakeholders within and outside of our company. Actively participate in conferences, industry events, and scientific forums to stay informed about emerging trends, expand our visibility, and establish strategic alliances that amplify Discovery Chemistry's impact at our company and on the broader scientific community. Cultivate relationships that reinforce our leadership in drug discovery and create opportunities for transformative partnerships.

Lead and Develop Scientific Talent: Build, lead, and develop high-performing scientists and teams, fostering a culture of scientific excellence, inclusion, accountability, and continuous learning. Through coaching, mentoring, performance management, and succession planning, empower individuals to achieve their full potential and advance their careers. Create an environment that encourages innovation, collaboration, healthy debate, and shared ownership, while ensuring the organization has the capabilities, talent, and leadership needed to deliver on current and future strategic objectives. As a people manager, you will shape the culture of Discovery Chemistry and help develop the next generation of scientific leaders.

To excel in this role, you will need strong skills in scientific and people leadership, strategic thinking, effective communication, collaboration, balanced risk-taking, and a relentless pursuit of excellence. Your passion for science, unwavering commitment to patients, and ability to inspire and empower others and dedication to developing talent will set you apart.

Embark on a career journey where your expertise and leadership will shape the future of medicinal chemistry, driving innovations that transform healthcare. Together, let's push the boundaries of scientific discovery and make a meaningful difference in the lives of people worldwide.

QUALIFICATIONS:

Education:
  • Bachelor's (with 13+ years), Master's (with 9+ years) or Ph.D. (with 7+ years) in chemistry or related field with relevant industry experience in drug discovery


Required Experience and Skills:
  • Experience in bioconjugate chemistry, linker and payload design and drug discovery
  • Demonstrated experience in leading drug discovery projects.
  • Proficiency in complex problem-solving and the ability to influence strategy across organizational boundaries
  • Strong leadership, communication, and collaboration skills
  • Proven track record of influencing teams, departments, and the enterprise, with the ability to work and influence across functional boundaries


Preferred Experience and Skills:
  • Proven managerial experience with a track record of training, developing talent, and mentoring team members in the field of medicinal chemistry and drug discovery.


#EligibleforERP

Required Skills:
Bioconjugation, Chemistry, Drug Discovery Research, Leadership, Medicinal Chemistry, Project Leadership, Strategic Thinking, Synthetic Chemistry

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

The salary range for this role is
$194,100.00 - $305,600.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic/International

VISA Sponsorship:
Yes

Travel Requirements:
10%

Flexible Work Arrangements:
Not Applicable

Shift:
1st - Day

Valid Driving License:
No

Hazardous Material(s):
N/S

Job Posting End Date:
08/20/2026
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

Merck & Co, Inc Careers

Join the visionary team at Merck & Co, Inc, a global leader in healthcare dedicated to advancing the world of medicine. As part of our professional community, you'll find dynamic job opportunities that foster innovation and leadership across various fields. Merck & Co, Inc is not just a company; it's a place where you can make a difference.

Work You’ll Do

At Merck & Co, Inc, we are committed to improving global health through groundbreaking research and innovative healthcare solutions. Our team is at the forefront of developing new therapies and vaccines that significantly impact public health worldwide. By joining us, you will collaborate with some of the brightest minds in the industry, using your skills to contribute to projects that save and improve lives around the globe.

Explore Career Paths

Whether you're seeking an internship, a graduate opportunity, or a professional position, Merck & Co, Inc offers a range of career paths in environments that promote rapid professional growth and development. Explore job opportunities in research, digital transformation, manufacturing, and more, all while benefiting from a culture that supports diversity and inclusion.

Innovate and Lead

Merck & Co, Inc is an ideal environment for those who lead with curiosity and the drive to innovate. Our leadership is committed to fostering a culture where inventive thinking and collaboration are encouraged, making it a perfect place for professionals who seek to make an impact through their work.

Develop Your Skills

With Merck & Co, Inc, you are not just getting a job; you're gaining access to unparalleled career development opportunities. Enhance your skills through diverse training programs, workshops, and continuous learning courses designed to help you grow at every stage of your career.

Benefits and Culture

We understand that our employees are our greatest asset, which is why we offer competitive benefits designed to support the health and well-being of you and your family. From comprehensive health care coverage and retirement plans to flexible working conditions and wellness programs, our benefits package is designed to meet the diverse needs of our team members.

Join Our Team

Ready to advance your career at Merck & Co, Inc? Search open positions that match your skills and interests. We are continuously hiring and looking for passionate, creative, and solution-driven team players. Prepare your resume, sharpen your interview skills, and become part of a company that's dedicated to making a difference.

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Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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