Director, Commercial IT Systems

Praxis Precision Medicines, Inc.

$190K — $220K *
US-AnywhereRemote in United States
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 10+ years in commercial technology or related roles leading cross-functional initiatives.
  • Pharmaceutical or biotechnology experience, especially with product launches.
  • Strong CRM, commercial data, and digital engagement knowledge; familiarity with Veeva or Salesforce.
  • Proven ability to translate strategy into actionable plans and manage budgets.
  • Technical fluency in data flows and integration patterns for effective collaboration with technical teams.
  • Experience in requirements definition, user acceptance testing, and change management.
  • Judgment in handling sensitive healthcare data and navigating compliance with cross-functional teams.
  • Effective communicator with a track record of influencing stakeholders and building teams.

Responsibilities

  • Own commercial systems strategy and roadmap, aligning business objectives with investments and outcomes.
  • Establish decision-making ownership for commercial systems and prioritize stakeholder needs.
  • Lead delivery of commercial systems from planning to adoption, managing risks and timelines.
  • Define business requirements for CRM and related data workflows, ensuring operational alignment.
  • Collaborate with Data & Analytics to develop reporting capabilities and maintain data integrity.
  • Manage vendor relationships and oversee commercial systems investment planning.
  • Facilitate readiness, training, and change management for system launches, with clear metrics for success.
  • Ensure compliance with access controls and data stewardship across commercial workflows.

Benefits

  • 99% of premiums covered for medical, dental, and vision plans.
  • Company-paid life insurance, AD&D, and disability benefits.
  • Dollar-for-dollar 401(k) match up to 6% with additional stock incentives.
  • Discretionary quarterly bonuses and generous PTO policy.
  • Flexible wellness benefits and company-wide shutdowns for work-life balance.
  • Collaborative and inspiring company culture focused on high achievement.
Full Job Description
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

Primary Responsibilities
  • Own the commercial systems strategy and roadmap. Translate launch milestones and business objectives into sequenced investments, clear priorities, and measurable outcomes across CRM, commercial data, field enablement, and connected commercial platforms.
  • Establish business ownership and decision-making for commercial systems. Align stakeholders on requirements, process changes, data definitions, priorities, and acceptance criteria; resolve competing demands and escalate material tradeoffs.
  • Lead commercial systems delivery from planning through adoption. Coordinate internal teams and implementation partners, manage dependencies and risks, and hold owners accountable for milestones, quality, and operational readiness.
  • Own business requirements and service expectations for CRM and its connections to commercial data, digital engagement, and relevant ERP workflows. Partner with enterprise application owners to ensure end-to-end processes work across organizational boundaries.
  • Partner with Data & Analytics to define the commercial data and reporting capabilities needed for launch and growth, including source requirements, data quality, timeliness, and business definitions. Establish dependable access to critical information and continuity when AI interfaces are unavailable.
  • Own vendor performance, service expectations, and the commercial systems investment plan. Lead business cases, evaluate platform choices, and manage approved budgets, license utilization, and renewals with IT, Finance, Procurement, and Legal.
  • Lead launch readiness, user acceptance, training, and change management with business owners. Establish adoption measures, support coverage, escalation paths, and contingency plans before systems become business-critical.
  • Partner with IT, Security, Privacy, Legal, and Quality to incorporate access controls, data stewardship, change control, and applicable compliance requirements into commercial workflows and vendor delivery.

Qualifications
  • 10+ years of relevant experience in commercial technology, enterprise applications, commercial operations systems, or related roles, including leadership of complex cross-functional initiatives.
  • Experience supporting pharmaceutical or biotechnology commercial operations, with a track record delivering systems for a product launch or significant commercial expansion.
  • Strong understanding of CRM, field workflows, commercial data, digital engagement, and the integrations that connect them. Experience with Veeva, Salesforce, or comparable enterprise platforms.
  • Ability to translate commercial strategy into a practical roadmap, business cases, priorities, and measurable outcomes; experience managing technology vendors and budgets.
  • Technical fluency in data flows, APIs, integration patterns, and cloud data platforms sufficient to challenge designs, assess dependencies, and guide delivery with engineering and analytics teams.
  • Experience leading requirements definition, user acceptance testing, change management, training, and transition to ongoing support.
  • Sound judgment in handling sensitive commercial and healthcare data, with experience partnering across IT, Security, Legal, Privacy, and Quality.
  • Clear communication, effective influence across functions, and a track record developing team capability and holding internal and external partners accountable.
  • Launch readiness: Critical commercial workflows are tested, supported, and ready when the business needs them.
  • Clear ownership: Decisions, priorities, and accountability are explicit; issues move to resolution without repeated executive intervention.
  • Business impact: Systems are adopted, data is trusted, and investments deliver measurable improvements in commercial execution.
  • Practical leadership and caring candor: You simplify complexity, surface risks early, challenge assumptions respectfully, and build strong delivery partnerships.
  • The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.


Annualized Base Salary

$190,000-$220,000 USD

Compensation & BenefitsAt Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let's achieve the impossible together!

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