Director, CGT Technology

Vertex Pharmaceuticals Incorporated

$198K — $297K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in IT, Computer Science, Engineering, Business, or related field; advanced degree preferred.
  • Leadership experience in business engagement or technology strategy.
  • Experience collaborating with business leaders on technology roadmaps.
  • Proven track record in managing complex project portfolios.
  • Strong understanding of data and AI-enabled business solutions.

Responsibilities

  • Serve as a strategic technology partner for the Commercial Cell and Gene Therapy business unit.
  • Define and lead the data, technology, and AI roadmap.
  • Act as the primary liaison between the business and DTE.
  • Shape and prioritize project portfolio in alignment with strategic business goals.
  • Oversee execution of large projects, ensuring delivery meets expectations.
  • Translate business strategies into actionable technology initiatives.
  • Identify opportunities to leverage data and AI for improved business outcomes.

Benefits

  • Comprehensive medical, dental, and vision coverage.
  • Paid time off and company holidays.
  • Professional development opportunities.
  • Inclusive and collaborative work environment.
  • Opportunities to impact patients globally.
Full Job Description
Job Description
Director, Business Engagement & Technology - Commercial Cell and Gene Therapy

Location: Hybrid or On-site
Role Summary

The Director of Business Engagement & Technology will serve as the strategic technology leader supporting the Commercial CGT business unit. This role is responsible for shaping and executing the data, technology, and AI roadmap that enables the business to scale global operations effectively.

This leader will act as the primary DTE partner, ensuring strong alignment between business priorities and technology strategy. The role will drive portfolio planning, oversee project execution, and partner across teams to deliver business value through modern, scalable, and compliant technology solutions.
Key Responsibilities
• Serve as a strategic technology partner for the Commercial Cell and Gene Therapy business unit.
• Define and lead the data, technology, and AI roadmap to support business growth and global operational scale.
• Act as the primary liaison and trusted advisor between the business and DTE.
• Shape, prioritize, and manage the project portfolio to align with strategic business goals and enterprise technology priorities.
• Oversee large project execution, ensuring delivery against scope, timeline, budget, and expectations
• Translate business strategies and operational needs into actionable technology initiatives and solution roadmaps.
• Partner with cross-functional stakeholders across DTE, Commercial, Supply Chain, Quality and others
• Identify opportunities to leverage data, digital platforms, and AI capabilities to improve decision-making, efficiency, and business outcomes.
• Drive governance, planning, and communication processes for technology investments and program delivery.
• Ensure solutions are scalable, secure, compliant, and aligned with enterprise architecture standards.
• Monitor evolving business needs, industry trends, and emerging technologies to continuously enhance the technology strategy.
• Build strong stakeholder relationships and influence decision-making at senior leadership levels.
Required Qualifications
• Bachelor's degree in Information Technology, Computer Science, Engineering, Business, or a related field; advanced degree preferred.
• Significant leadership experience in business engagement, technology strategy, digital transformation, or related roles.
• Demonstrated experience partnering with business leaders to define and deliver technology roadmaps tied to strategic outcomes.
• Proven success managing complex project portfolios and leading cross-functional technology initiatives.
• Experience overseeing project execution in a matrixed, global organization.
• Strong understanding of data, enterprise technology platforms, and AI-enabled business solutions.
• Ability to bridge business strategy and technical execution with strong communication and influencing skills.
• Experience serving as a primary business partner or relationship manager for technology functions.
• Strong organizational, prioritization, and decision-making skills.
• Ability to operate effectively in a fast-paced, highly collaborative environment.
Technical Skills Required
• Technology roadmap development
• Data strategy and enablement
• AI and advanced analytics strategy
• Project portfolio management
• Program and project execution oversight
• Business relationship management
• Digital transformation leadership
• Cross-functional stakeholder management
• Enterprise technology planning
• Governance and prioritization frameworks
• Scalable global operations support
• Technology-business alignment
• Budget management
Preferred Skills
• Experience supporting Commercial, Cell and Gene Therapy, or Hematology-focused business functions.
• Commercial technology and GxP system expertise, including experience with platforms such as Salesforce
• Familiarity with regulated industry environments such as biotechnology, pharmaceuticals, or healthcare.
• Experience with global technology deployments and change management.
• Strong understanding of enterprise data ecosystems, reporting, and analytics capabilities.
• Ability to identify and implement innovative digital and AI solutions that improve commercial effectiveness.
• Experience working within a Data, Technology & Engineering or similar enterprise technology function.
• Executive presence with the ability to communicate strategy, risks, and progress to senior stakeholders.
Benefits

Vertex offers a competitive and comprehensive rewards package designed to support employees' well-being, growth, and success. Benefits may include:
• Competitive base salary and incentive compensation
• Comprehensive medical, dental, and vision coverage
• Retirement savings programs
• Paid time off and company holidays
• Professional development and learning opportunities
• Wellness and employee assistance programs
• Inclusive and collaborative work environment
• Opportunities to contribute to transformative work that impacts patients globally

Pay Range:
$198,000 - $297,000

Flex Designation:
Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

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