Roche

Commercial Affordability Principal Project Manager

Roche$136K — $252K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree with 5–7 years of relevant experience in vendor management or project management.
  • Strong project management skills in operational processes.
  • Excellent communication and presentation skills for engaging diverse audiences.
  • Experience with regulatory processes and compliance in pharmaceuticals or biotechnology.
  • Ability to manage and motivate external vendors effectively.

Responsibilities

  • Own day-to-day operations for multiple commercial affordability programs.
  • Manage external vendor performance, ensuring accountability for SLAs and KPIs.
  • Lead complex, cross-functional initiatives, including program launches and regulatory updates.
  • Perform root-cause analysis and translate insights into improvements.
  • Interpret program performance data for actionable insights and audit readiness.
  • Act as a subject matter expert for cross-functional teams across brand, finance, and compliance.
  • Ensure program compliance with regulatory guidelines and internal policies.

Benefits

  • Hybrid work schedule with three days on-campus in South San Francisco.
  • Potential eligibility for a discretionary annual bonus based on performance.
Full Job Description

The Opportunity

As the Commercial Affordability Principal Project Manager, you will serve as a key cross-portfolio subject matter expert driving the end-to-end operational execution of Genentech’s commercial affordability programs (including Co-pay, Bridge/Starter, Coupon other patient free goods programs). You can expect to:

  • Own day-to-day operations for multiple commercial affordability programs across diverse brand and therapeutic areas.

  • Manage external vendor performance, driving accountability for SLAs, KPIs, service quality, and complex issue escalations.

  • Lead complex, cross-functional operational initiatives, including program launches, system enhancements, and regulatory updates.

  • Perform root-cause analysis on systemic operational issues and translate insights into scalable portfolio improvements.

  • Interpret program performance data (utilization, access, speed to therapy) to deliver actionable insights and maintain audit readiness.

  • Act as a primary subject matter expert and cross-functional integrator across brand teams, finance, compliance, and Patient Experience (PX).

  • Ensure strict program compliance with regulatory guidelines, internal policies, and operational guardrails.

Who you are

  • You hold a Bachelor’s degree and 5–7 years of relevant experience in vendor management, operations, or project management.

  • You possess strong project management skills with direct experience owning operational processes and driving tactical execution.

  • You demonstrate excellence in communication and presentation skills, with proven ability to effectively engage and educate high-level, diverse audiences on brand and program strategies, translating complex recommendations into clear, actionable guidance

  • You have proven experience navigating and adhering to strict regulatory processes and compliance-driven environments.

  • You demonstrate the ability to manage, motivate, and hold external vendors accountable through clear communication and escalation management.

Preferred

  • Prior experience within commercial affordability, patient access, in the pharmaceutical or biotechnology sector.

  • Proven track record of cross-functional leadership and influencing without authority within a complex matrixed organization.

Location

  • This role is based in South San Francisco and offers a hybrid schedule working 3 days per week on campus

  • No relocation benefits are available for this posting

The expected salary range for this position based on the primary location of CA is $136,100 - 252,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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