The Duke Cancer Institute's Phase 1 and Immunotherapy Program (PHIIT) is seeking a highly skilled Clinical Research Nurse Coordinator to join our dynamic Oncology Clinical Research Unit (CRU). In this critical role, you will lead and coordinate complex oncology clinical trials, including first-in-human studies and investigational therapies that are advancing the future of cancer care. You will work at the forefront of innovation-partnering closely with physicians, researchers, and multidisciplinary teams to bring cutting-edge treatments to patients. From study start-up through closeout, you will be a central driver of clinical trial execution, ensuring excellence in patient care, regulatory compliance, and data integrity. In your day-to-day work, you will engage directly with patients-guiding them through the clinical trial process, administering specialized treatments such as chemotherapy, monitoring for adverse events, and providing education on investigational therapies. You will also collaborate with sponsors, manage study operations, and contribute to the development of new research initiatives. This is an exceptional opportunity for a nurse who is passionate about oncology, research, and patient-centered care to make a meaningful impact in advancing life-saving therapies. Minimum Requirements: - Graduation from an accredited BSN program, Associate Degree in Nursing, or Nursing Diploma program - Current or compact RN licensure in the state of North Carolina - BLS certification required - Minimum 12 months of clinical nursing experience - If not BSN-prepared, must enroll in a BSN program within two years and complete within seven years - Maintain compliance with all hospital and unit-specific competencies and training requirements Preferred Qualifications: - Experience in oncology, clinical research, or intensive care (ICU) - Experience with clinical trials, investigational products, or protocol-driven care - Familiarity with Electronic Data Capture (EDC) systems and research documentation - Strong ability to manage complex workflows and collaborate with multidisciplinary teams Other Requirements: - Ability to administer adult chemotherapy and ambulatory medications - Clinical competencies including dysrhythmia review, lab interpretation, and adverse event assessment - Participation in continuing education and maintenance of required certifications Position Description: - Coordinate and manage oncology clinical trials by recruiting, screening, consenting, and enrolling participants while ensuring adherence to study protocols and regulatory requirements - Deliver direct patient care in a research setting, including medication administration, chemotherapy delivery, patient education, and monitoring for adverse events and treatment compliance - Oversee study operations and compliance, maintaining regulatory documentation, reporting adverse events, supporting audits, and ensuring alignment with institutional policies, SOPs, and federal guidelines - Collaborate with investigators, sponsors, and cross-functional teams to execute study activities, resolve issues, support monitoring visits, and contribute to study start-up and closeout processes - Support financial and data management efforts, including budget development, tracking study milestones, entering and validating clinical data, and ensuring data accuracy, security, and completeness Job Level: 54 Anticipated Pay Range: Duke University provides an annual base salary range for this position as USD $66,265.00 to USD $107,096.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer. Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: https://hr.duke.edu/benefits/