St. Jude Children's Research Hospital

Chemistry Associate Scientist in Kalodimos Lab

Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Extensive hands-on experience in multi-step gram-scale synthesis of complex compounds.
  • Strong expertise in amino acid purification and analytical methods.
  • Solid understanding of protein NMR applications using stable isotopes.
  • Familiarity with cell-based and cell-free protein synthesis systems for stable isotope-labeled proteins.
  • Demonstrated ability to manage multiple research projects and maintain thorough documentation.

Responsibilities

  • Design, synthesize, and optimize stable isotope-labeled amino acids and derivatives for NMR studies.
  • Perform separation, purification, and analytical characterization of amino acids.
  • Operate and maintain synthetic chemistry equipment while managing personal synthesis schedules.
  • Deliver synthesized reagents to the protein preparation team to meet project deadlines.

Benefits

  • Comprehensive medical, dental, and vision plans.
  • Affordable medical premiums for employees and dependents.
  • Financial security and retirement plans.
  • Wellness programs focusing on employee health.
  • Educational and family-friendly benefits unique to St. Jude.
Full Job Description
We are seeking an Associate Scientist to join our Blue Sky Protein Kinases team in the Department of Structural Biology at St. Jude Children's Research Hospital.

Key Responsibilities for this Role
  • Design, synthesize, and optimize stable isotope-labeled amino acids and related derivatives that serve as precursors for isotope-labeled proteins used in protein NMR studies.
  • Perform separation, purification, and analytical characterization of amino acids.
  • Operate and perform routine maintenance of synthetic chemistry equipment, and manage personal synthesis schedules to ensure timely project completion.
  • Deliver synthesized reagents to the protein preparation team in a timely manner to meet project deadlines.


Preferred Candidate
  • Extensive hands-on experience in multi-step (≥10 steps) gram-scale synthesis of complex compounds; experience with stable isotope-labeled compounds is highly desirable.
  • Strong expertise in amino acid purification and analytical methods.
  • Solid understanding of protein NMR applications utilizing stable isotopes.
  • Familiarity with cell-based (e.g., bacterial or insect) and cell-free protein synthesis systems for stable isotope-labeled protein production.
  • Demonstrated ability to manage multiple research projects simultaneously, maintain thorough daily documentation of experimental work, and consistently meet deadlines.


Minimum Education and/or Training
  • Bachelor's degree in a relevant scientific area.


Minimum Experience
  • 7 + years of research experience is required with a Bachelor's degree.
  • 5 + years of research experience is required with a Master's degree.
  • 2 + years of research experience is required with a PhD.


Benefits

Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices.

We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents.

View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Chemistry Associate Scientist in Kalodimos Lab.

Explore our exceptional benefits!

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

About St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is a pediatric treatment and research facility focused on children's catastrophic diseases, particularly leukemia and other cancers. The hospital was founded in 1962 by entertainer Danny Thomas and is located in Memphis, Tennessee. St. Jude is the first and only pediatric cancer center to be designated as a Comprehensive Cancer Center by the National Cancer Institute. The hospital has treated children from all 50 states and from around the world. St. Jude is known for its groundbreaking research and treatment of childhood cancer and other life-threatening diseases.
Learn more about St. Jude Children's Research Hospital
Size
4,500 employees
Industry
Founded
1962

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