Job Title

Principal Business Analyst, Cell & Gene Therapy Commercial Technology

Role Summary

Vertex is seeking a Principal Business Analyst, Cell & Gene Therapy Commercial Technology to join the Data, Technology and Engineering (DTE)team and play a key role in shaping and supporting technology solutions for our Cell & Gene Therapy commercial organization. This individual will partner closely with commercial stakeholders and technology teams to define business needs, improve processes, and enable scalable digital capabilities that support scaling operations, order management, analytics, and end to end patient journey across multiple platforms and technologies.

The ideal candidate will bring strong business analysis expertise, deep stakeholder management skills, experience delivering AI and automationand supporting commercial functions within biotechnology, pharmaceuticals, or other regulated industries. This role requires a blend of strategic thinking, process optimization, and hands-on delivery support to ensure technology solutions align with business priorities and compliance expectations.

Work Model: Hybrid or on-site

Key Responsibilities

 Partner with Commercial, Cell & Gene Therapy, and Technology stakeholders to understand business strategies, priorities, and operational challenges

 Lead requirements gathering, business process analysis, and solution design for complex commercial technology initiatives

 Translate business needs into detailed functional requirements, user stories, process maps, business rules, and solution recommendations

 Support technology initiatives across key commercial domains such as patient services, order management, field enablement, commercial analytics, and data integration

- Partner with business and technical teams to help define and deliver AI and automation usecases aligned to business priorities

 Analyze current-state and future-state business processes to identify opportunities for standardization, automation, and optimization

 Facilitate cross-functional workshops and working sessions to align stakeholders on priorities, requirements, and solution outcomes

 Collaborate with product managers, architects, developers, data teams, and vendors to ensure solutions meet business objectives and enterprise standards

 Drive business readiness activities including testing support, user acceptance testing, training coordination, adoption planning, and change management

 Ensure solutions align with relevant compliance, privacy, legal, promotional review, and regulated industry requirements

 Develop and maintain high-quality documentation including business requirements, process flows, use cases, impact assessments, and traceability artifacts

 Use data, metrics, and stakeholder feedback to evaluate solution effectiveness and support continuous improvement

 Contribute to business analysis best practices across the commercial technology organization

Required Qualifications

 Bachelors degree in Business, Information Systems, Life Sciences, Engineering, or a related field

 Significant experience in business analysis, product delivery, process improvement, or related roles within biotechnology, pharmaceuticals, healthcare, or another regulated industry

 Experience supporting commercial business functions and technology platforms, preferably in life sciences

 Demonstrated ability to lead complex, cross-functional initiatives involving multiple business and technical stakeholders

 Strong experience eliciting, documenting, validating, and managing business and functional requirements

 Proven ability to analyze and improve business processes and translate them into technology-enabled solutions

- Experience supporting or contributing to automation, advanced analytics, AI-enabled, or digital transformation initiatives

 Experience working across the system or product delivery lifecycle, including planning, requirements, testing, implementation, and post-go-live support

 Excellent communication, facilitation, presentation, and stakeholder management skills

 Strong analytical, problem-solving, and organizational abilities

 Understanding of compliance and documentation expectations in regulated business environments

Technical Skills Required

 Business and functional requirements documentation

 Process mapping and business workflow analysis

 User story creation and backlog refinement

 Gap analysis and solution assessment

 Data analysis, reporting, and dashboard requirements support

 Stakeholder workshop facilitation

 User acceptance testing support and test scenario development

 Change management and training support

 Familiarity with CRM and commercial technology ecosystems

- Understanding of AI-enabled business solutions, workflow automation, and process digitization concepts

 Knowledge of Agile, Waterfall, or hybrid project delivery methodologies

 Proficiency with tools such as Jira, Confluence, Visio, Microsoft Excel, PowerPoint, Word, and other collaboration platforms

 Understanding of enterprise data flows, integrations, and commercial reporting environments

Preferred Skills

 Experience supporting Cell & Gene Therapy commercial business models and technology capabilities, including Salesforce and AI

 Knowledge of pharmaceutical or biotech commercial operations, including field engagement, market access, patient support, and launch planning

 Experience with platforms such as CRM systems, data visualization tools, customer engagement platforms, and commercial analytics solutions

- Experience with AI use case definition, intelligent automation, workflow tools, or emerging digital technologies in support of business operations

 Familiarity with patient services, specialty distribution, HUB operations, and reimbursement-related workflows

 Experience with digital transformation, automation, and master data or system integration initiatives

 Understanding of privacy, promotional, legal, and compliance considerations in commercial technology

 Relevant certifications such as CBAP, PMI-PBA, Agile, Scrum, or Lean Six Sigma

 Advanced degree in Business, Information Systems, Life Sciences, or a related discipline