Job Family:Scientist
Travel Required:None
Clearance Required:Ability to Obtain Public Trust
What You Will Do:We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible.
Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.
- Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.
- Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/metagenome integration, and biological discovery.
- Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.
- Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.
- Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.
- Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.
What You Will Need:- Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.
- Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.
- Hands-on background analyzing next-generation sequencing data and genomic datasets.
- Working knowledge of Genome-Wide Association Studies (GWAS).
- Background performing bulk RNA sequencing analysis.
- Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.
- Ability to work with large and complex biological datasets.
- Proven ability to develop bioinformatics pipelines and analytical workflows.
- Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.
- Demonstrated ability to collaborate with multidisciplinary scientific teams.
- Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.
- Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.
What Would Be Nice To Have:- Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.
- Background supporting federal biomedical or environmental health research programs.
- Strong written and verbal communication skills, including presentation experience.
- Ability to develop custom bioinformatics applications and advanced computational algorithms.
- Familiarity supporting high-performance computing environments.
- Ability to provide bioinformatics training, mentoring, and instructional support.
- Demonstrated contributions to scientific manuscripts and peer-reviewed publications.
- Collaboration across interdisciplinary genomic, epidemiologic, and population-based research programs.
What We Offer:Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
- Medical, Rx, Dental & Vision Insurance
- Personal and Family Sick Time & Company Paid Holidays
- Parental Leave
- 401(k) Retirement Plan
- Group Term Life and Travel Assistance
- Voluntary Life and AD&D Insurance
- Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
- Transit and Parking Commuter Benefits
- Short-Term & Long-Term Disability
- Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
- Employee Referral Program
- Corporate Sponsored Events & Community Outreach
- Care.com annual membership
- Employee Assistance Program
- Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
- Position may be eligible for a discretionary variable incentive bonus