Bioinformatics Engineer, Therapeutics

LatchBio

$120K — $180K *
US-Anywhere
+ 2 other locationsRemote
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 2+ years in biologics discovery or development (antibody/protein engineering, target validation)
  • Experience with binding kinetics (SPR/BLI) and biophysical data
  • Proficient in Python and/or R for analysis and visualization
  • Familiarity with antibody optimization or protein structure tools
  • Knowledge of PK/PD modeling or bioprocess/manufacturability constraints

Responsibilities

  • Contribute to AI-driven analysis of complex therapeutics datasets
  • Collaborate with software engineers and biologists on dataset development
  • Support the discovery pipeline through data-driven strategies
  • Enhance agents’ reasoning capabilities within data frameworks
  • Engage in end-to-end data analysis from experimental data to scientific decision-making

Benefits

  • Free lunch and dinner provided
  • Waterfront office location in China Basin, San Francisco
  • Option for full-time remote work
Full Job Description
We9re seeking a Bioinformatics Engineer for Therapeutics to join our therapeutics bench, working at the frontier of what artificial intelligence can achieve in biology.

About the Role

You will contribute to our technical approach to teaching agents how to understand and handle complex therapeutics datasets, working across end-to-end data analysis workflows from practical therapeutics data to real scientific decisions.

You will work as part of a team of software engineers and biologists building datasets to teach these agents to reason better across the discovery pipeline.

Requirements
  • 2+ years hands-on experience with biologics discovery or development (antibody engineering, protein engineering, or cell/molecular biology-driven target validation)
  • Experience interpreting binding kinetics (SPR/BLI), biophysical stability data, and/or cell-based potency assays
  • Proficiency in Python and/or R for data analysis & visualization
  • Familiarity with at least one of:
    • Antibody optimization (CDR engineering, VH/VL pairing, variant screening)
    • Protein structure (AlphaFold, cryo-EM, docking)
    • High-throughput antibody/binding screens
    • PK/PD modeling for biologics (target occupancy, half-life, clearance) -
    • Bioprocess/manufacturability constraints

Nice-to-Have
  • Experience with immunogenicity risk assessment
  • Hands-on work with potency assay design (ELISA, cell-based, biochemical)
  • CMC/GMP-adjacent knowledge

Compensation & Logistics
  • OTE 120k - 180k - Performance based pay
  • Free meals (lunch and dinner)
  • Waterfront office in China Basin, San Francisco
  • Full-time, in-person (can be remote)

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