Work ScheduleStandard (Mon-Fri)
Environmental ConditionsOffice
Job DescriptionBioinformatics Content ManagerYou will lead a team of variant scientists within the Clinical Next Generation Sequencing Division, providing scientific, operational, and people leadership to support the development and maintenance of genomic knowledge resources, variant interpretation frameworks, and clinical reporting solutions. In this role, you will oversee the evaluation, analysis, and synthesis of complex clinical and scientific evidence from primary literature, clinical guidelines, and clinical trials to support precision oncology applications. You will be accountable for ensuring the quality, consistency, and scalability of scientific curation and interpretation activities while aligning team priorities with organizational objectives.
As a people leader, you will recruit, develop, mentor, and retain a high-performing team of scientists, fostering a culture of scientific excellence, collaboration, continuous improvement, and accountability. You will partner closely with scientific, technical, clinical, product, and business stakeholders to define resource allocation, establish priorities, and deliver key organizational initiatives.
Success in this role requires deep expertise in cancer genomics and variant interpretation, strong leadership and organizational skills, and the ability to balance scientific rigor with operational execution and compliance in a fast-paced, cross-functional environment. The mission of this business unit is to develop next-generation sequencing-based solutions to support oncology research and other important unmet medical needs.
LocationThis is a fully onsite role based in Ann Arbor, MI and relocation assistance is not provided.
A Day in the Life- Oversee the interpretation, analysis, and summarization of clinical evidence to support somatic and germline variant annotation, classification, and reporting.
- Define and drive content prioritization strategies while managing team capacity, workload allocation, product initiatives, assay development activities, and operational commitments.
- Provide subject matter expertise throughout the assay development lifecycle, including requirements definition, evidence strategy, incorporation of clinical evidence and variant interpretation standards, validation support, and product launch activities.
- Partner with software product owners and engineering teams to optimize and deliver a user-centered scientific user experience of the research and clinical workflows.
- Collaborate across product, quality, regulatory, and clinical functions to deliver compliant, high-quality research use or regulated products.
- Lead continuous improvement efforts to strengthen scientific rigor, data quality, operational efficiency, and organizational scalability.
- Lead and develop a high-performing team of scientists through talent acquisition, performance management, coaching, and career development.
- Monitor team performance, project progress, key deliverables, risks, and resource utilization, proactively implementing mitigation strategies to ensure successful execution.
- Collaborate with leadership to develop strategic roadmaps, organizational priorities, and long-term capability plans informed by customer, market, scientific, and industry trends.
- Foster a culture of accountability, inclusion, innovation, and continuous improvement.
Keys to SuccessEducationPhD in cancer biology, cancer genomics, or molecular biology with expertise in solid/heme cancer genomics, tumor biology, signaling pathway, variant interpretation and NGS technologies. Post-doctoral experience is preferred.
Experience- 4+ years of relevant experience; industry based experience in genomic variant curation and clinical interpretation for somatic and germline cancers preferred.
- Demonstrated people management experience is preferred.
- Proven ability to manage multiple priorities and resources in a dynamic environment.
- Proven ability to build effective partnerships and influence decision-making across scientific, technical, clinical, and business functions.
- Experience with regulatory submissions, assay development, or genetic counseling is a plus.
Knowledge, Skills, Abilities- Excellent organizational, communication, and stakeholder management skills.
- Strong leadership, coaching, mentoring, and performance management skills.
- Experience driving continuous improvement and operational excellence initiatives.
- Strong strategic thinking, problem-solving, and decision-making skills.
- Commitment to fostering an inclusive, collaborative, and high-performance team culture.
Other- Must be legally authorized to work in the United States without sponsorship now or in the future.
- Must be able to pass a comprehensive background check and drug screen.
