Entity: Technology
Job Family Group: Research & Technology Group
Job Description: The scientist will join our Biochemistry Team and will contribute to high-priority projects by characterizing enzyme activities and biochemical conversions and by engineering enzymes to advance low-carbon technologies. The individual will collaborate with a group of engineers and scientists including Synthetic Biology, Analytical Chemistry, Computational Biology, & Bioprocess teams. The scientist will bring expertise in enzyme characterization and screening and bring a keen interest in scientific discovery.
Key Accountabilities - Spend 50-75% of their time to build and conduct wet-lab experiments to characterize enzyme activity and perform qualitative and quantitative analysis of substrates and products via biochemical assays.
- Be a subject matter expert in key enzymes of interest through review of literature and patents and will make recommendations to guide research accordingly.
- This role will collaborate with cross-functional teams to discover improved enzyme sequences through a combination of sequence, structural, and/or computational methods.
- Participate in maintaining equipment, consumables, inventory, and safe practices, will write detailed SOPs, will maintain detailed records in Benchling, and will manage large data sets.
- This role will frequently update teams (typically through concise presentations) and will show aptitude for communicating and creating meaningful team interactions.
- This role will promote safety initiatives and champion compliance with BP's Code of Conduct.
Essential Criteria and Qualifications - Enzymology: Knowhow and experience in enzyme functional characterization, identification of enzymes in crude mixtures, enzyme quantification, stability testing, and determination of constants from enzyme steady-state kinetic testing.
- Development of biochemical assays: including coupled assays, endpoint and continuous.
- Develop data analysis and visualization from high-throughput and quantitative experiments including statistical significance of conclusions.
- Communication: Excellent written and verbal communication skills with the ability to effectively collaborate with cross-functional teams and make concise summaries.
- Organization:Ability to prioritize responsibilities, respond flexibly to changing priorities, and work effectively in a multitasking and matrix environment.
- Safety:Ensure all laboratory and process development activities follow standard operating procedures (SOPs), environmental health and safety (EHS) guidelines, and quality standards at bp Biosciences Center.
Other Desirable Experience: - Hands-on experience with automation platforms and high-throughput assay development.
- Hands-on experience in biochemical characterization of saccharides and oligo-saccharides.
- Hands-on experience in synthetic biology techniques, protein expression platforms, protein purification.
- Experience in protein structure/function predictions, substrate docking, MD, AI-based protein engineering tools and services.
- Experience in biofuels research.
Education PhD degree in Biochemistry, Molecular Biology, or Bioengineering, or Master's plus minimum of 5 years of proven experience.
How much do we pay (Base)? $102,000 - $170,000 USD
*Note that the base pay range listed for this position is a good faith and reasonable estimate of the range of possible base compensation at the time of posting.
We offer a reward and wellbeing package to enable your work to fit with your life. These can include, but are not limited to, access to health, vision and dental insurance, flexible working schedule, paid time off policy, discretionary annual bonus program, long-term incentive program, and a generous 401K matching program. You may learn more about our generous benefits at benefits@bp.
Travel RequirementNegligible travel should be expected with this role
Relocation Assistance:This role is not eligible for relocation
Remote Type:This position is not available for remote working
Skills:Agility core practices, Analytical Thinking, Bioprocess Design, Chemical kinetic modelling, Collaboration, Communication, Creativity and Innovation, Curiosity, Experimental Design, Industry technology knowledge, Intellectual Asset Management, Life cycle and circularity, Multi-physics modelling, New process technology scale-up, Novel process development, Pilot and demonstration plant operation, Presenting, Problem Solving, Process Safety Engineering, Science and Technology Leadership, Scientific publication, Talent Matching, Technoeconomic evaluation of processes, Thermophysical modelling, Thought Leadership
