AstraZeneca

Associate Scientist, Process Development

AstraZeneca$79K — $119K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Hands-on experience in engineered TCR T cell therapies.
  • Experience with genome editing tools including DNA/RNA transfection methods.
  • Familiarity with process development for cell therapies, particularly in scale-up and functional assay result interpretation.
  • Experience in authoring manufacturing batch records.
  • Strong organizational and time management skills.
  • Excellent communication and teamwork abilities.
  • Proficient in Microsoft Office Suite (Word, Excel, Outlook, and PowerPoint).

Responsibilities

  • Support experimental design and execute experiments for T cell product manufacturing processes.
  • Collect and analyze data, presenting findings in team discussions.
  • Assist in preparing critical process materials such as media and RNA complexes.
  • Aid in tech transfer of GMP processes to manufacturing organizations.
  • Stay updated on scientific advancements in cell therapy to evaluate new methodologies.
  • Maintain detailed lab notebooks and electronic records per company policies.
  • Contribute to the preparation of technical documents like SOPs and development reports.

Benefits

  • Qualified retirement program (401(k) plan).
  • Paid vacation and holidays.
  • Paid leaves.
  • Health benefits including medical, prescription drug, dental, and vision coverage.
Full Job Description
Associate Scientist, Process Development AstraZeneca isseekinga highly motivated researcher to join the Process Development team, as Associate Scientist, supporting and contributing to the design and execution of studies to develop andoptimizeclinical manufacturing processes ofAstraZenecasportfolio of engineered T cell therapies. As a member of the Process Development team, this rolewill alsosupporttechnology transfer to the clinicalproduction site.Based in Santa Monica, CA, this role reports to the Senior Scientist, Process Development. Essential Functions and Responsibilities Support experimental design and execute experiments to develop andoptimizemanufacturing processes for genome-engineered T cell products. Collect and analyze experimental data andpresentfindingsin team meetings. Collaborate within the project team to interpret study results and contribute to technical discussions forsubsequentstudy design. Provide support across different process development areas during high-volume activities.Prepare critical process materials including formulation of media and ribonucleic protein complexes. Assistwith process development and tech transfer of GMP manufacturing processes to internal and external manufacturing organizations. Stay current with scientific advancements and emerging technologies in cell therapy process development. Help evaluatenew technologiesand methodologies to enhance process efficiency. Maintainaccurateand detailed laboratory notebooks and electronic records in compliance with company policies and regulatory requirements. Assistin preparingtechnical documents, including standard operating procedures (SOPs), batch records, and development reports, as needed. Work effectively in a team environment to meet projecttimelineandobjectives. Perform other duties as assigned.Position may require weekend work. Required Skills Hands-on experience with the development ofengineered TCRT cell therapies. Hands-on experience with genome editing toolsincludingDNA/RNA transfection approaches. Familiar with process development for cell therapies, including scale-up andinterpretation ofT-cellfunctional assayresults(flow-cytometry, cytotoxicity, proliferation). Experience with authoring manufacturing batch records. Strong organizational and time management skills. Excellent teamwork and communicationskills,withthe ability to workcollaboratively cross-functionally. Proficiencywith MicrosoftOffice, including Word,Excel,Outlookand PowerPoint. Desired Skills Knowledge of cGMP manufacturing and practical experience in GMP operations. Experience withstatistical analysis software (e.g.JMP, GraphPad Prism) for analyzing and presenting data. Familiar with the fundamentals oftheDesign of Experiments approach. Education BS or MS degree inBiology,Biotechnology, Biomedical Engineering, or related field with 1+ years of experience for MS or 2+ years of experience with BS The annual base pay for this position ranges from $79,336.80 - $119,005.20. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 15-Jun-2026 Closing Date 29-Jun-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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