Career CategoryScientific
Job DescriptionAssociate Scientist - Cellular Assay Development, Functional GenomicsWhat you will doLet's do this. Let's change the world. In this vital role you will be part of a dynamic, cross-functional team to advance target and biological discovery across Amgen's therapeutic areas.
Key Responsibilities:
- Support the execution of functional arrayed genomic screens in advanced in vitro models in collaboration with therapeutic area partners.
- Carry out mammalian cell culture, transfection, transduction, and functional assays to enable functional, arrayed genomic screens; experience with iPSC culture and differentiation preferred.
- Optimize and miniaturize cell-based assays for high-throughput automated screening.
- Leverage functional assays, particularly high-content imaging, to profile cellular phenotypes and states.
- Partner with TD&B and cross-functional team members, including automation colleagues, to accelerate model deployment and reproducibility.
- Collaborate with Amgen therapeutic area scientists to define requirements, ensure biological relevance, and deliver systems that enable mechanistic and translational insights.
- Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen's pipeline.
What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a researcher with these qualifications.
Basic Qualifications:Master's degree and 1 year of scientific/drug discovery experience and track record of scientific excellence and productivity
OR
Bachelor's degree and 3 years of scientific/drug discovery experience and track record of scientific excellence and productivity
Preferred Qualifications:- M.S. degree in cell biology, molecular biology, biomedical engineering, or related discipline, or B.S. degree with commensurate scientific/drug discovery experience and track record of scientific excellence and productivity
- Proficiency with mammalian cell culture, including immortalized and primary lines required; experience with iPSC culture preferred
- Experience with gene editing/delivery techniques, i.e. CRISPR/Cas9, lentiviral transduction, and transient transfection
- Experience with cellular assay optimization and miniaturization; familiarity working with plate-based assays and associated equipment/automation
- Strong hands-on experience with functional assays, particularly high-content imaging
- Familiarity with high-throughput sreening metrics (e.g. Z', S/B, MSMR)
- Demonstrated ability to collaborate with cross-functional teams to translate disease biology into experimental models
- Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment
What you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.careers.amgen.comSalary Range94,340.65USD -127,637.35 USD