Eli Lilly

Associate Scientist, CAR Discover- Lilly Gene Therapy

Eli Lilly$71K — $187K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • BS or MS in Immunology, Molecular Biology, Cell Biology, Oncology, or a related field with 3-5+ years of industry experience.
  • Must be authorized to work in the US on a full-time basis without sponsorship.

Responsibilities

  • Lead design and execution of experiments for novel CAR construct discovery.
  • Develop innovative strategies for CAR optimization across various domains.
  • Apply molecular biology techniques for CAR construct generation and modification.
  • Perform in vitro functional assays using primary human T cells and tumor cell lines.
  • Design ex vivo studies to evaluate CAR T-cell efficacy and safety.
  • Analyze, interpret complex data, and present findings to stakeholders.
  • Collaborate with multidisciplinary teams and mentor junior scientists.

Benefits

  • Eligibility for a company-sponsored 401(k) and pension plan.
  • Vacation and leave of absence benefits.
  • Medical, dental, vision, and prescription drug benefits.
  • Flexible spending accounts for healthcare and dependent care.
  • Life insurance and death benefits.
  • Access to employee assistance programs and fitness benefits.
Full Job Description
The Lilly Gene Therapy Team is seeking a highly motivated and experienced scientist to join our CAR Discover team. This role will be instrumental in the design, development, and optimization of novel Chimeric Antigen Receptor (CAR) T-cell therapies, contributing to groundbreaking advancements in oncology.

Job Responsibilities:
  • Lead the design and execution of experiments for the discovery and characterization of novel CAR constructs.
  • Develop and implement innovative strategies for CAR optimization, including antigen-binding domains, costimulatory signaling, and intracellular signaling domains.
  • Apply molecular biology techniques (e.g., cloning, primer design, sequencing) for CAR construct generation and modification.
  • * Perform in vitro functional assays (e.g., cytotoxicity, cytokine production, proliferation, activation) using primary human T cells and various tumor cell lines.
  • Design and implement ex vivo studies to evaluate CAR T-cell efficacy and safety using patient-derived samples.
  • Analyze and interpret complex experimental data, present findings to internal and external partners, and contribute to scientific publications and patent applications.
  • Collaborate effectively with multidisciplinary teams, including immunology, oncology, process development, and manufacturing.
  • Mentor junior scientists and contribute to a culture of scientific excellence and innovation.
  • Stay abreast of innovative scientific literature and technological advancements in the CAR T-cell therapy field.
  • Maintain meticulous laboratory records and adhere to all relevant safety and regulatory guidelines.


Job Qualifications:
  • BS or MS in Immunology, Molecular Biology, Cell Biology, Oncology, or a related field with at least 3-5+ years of relevant industry experience
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.


Additional Skills/Preferences:
  • Extensive hands-on experience with CAR T-cell design, engineering, and functional characterization is essential.
  • Proficiency in a wide range of molecular biology techniques, including gene cloning, PCR, Western blotting, and CRISPR/Cas9 gene editing.
  • Demonstrated expertise in cell culture techniques, particularly with primary human T cells and mammalian cell lines.
  • Strong experience with flow cytometry for immunophenotyping and functional analysis.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

About Eli Lilly

ICOS Corporation is a biotechnology company that engages in the discovery, development, and commercialization of therapeutic products. It is engaged in the commercialization of treatments for unmet medical conditions, such as benign prostatic hyperplasia, hypertension, pulmonary arterial hypertension, cancer, and inflammatory diseases. It is the developer of a treatment known as Cialis (tadalafil), a product for the treatment of erectile dysfunction through its joint venture with Eli Lilly and Company in North America and Europe. It is also engaged in contract manufacturing services for third parties. It is in a strategic alliance with Solvay Pharmaceuticals, Inc. ICOS Corporation was established in 1989, based in Bothell, Washington. It is currently operated by Eli Lilly and Company.

Eli Lilly Careers

Joining Eli Lilly offers an unparalleled opportunity to become part of a leading global team dedicated to creating a healthier future. As a company revered for its commitment to innovation and leadership in the pharmaceutical industry, Eli Lilly is where your professional journey can flourish. Work You’ll Do At Eli Lilly, we are passionate about transforming patient care and advancing medical innovation. Our team at Eli Lilly is at the forefront of developing groundbreaking solutions in healthcare. By joining us, you will collaborate with some of the brightest minds in the industry, using cutting-edge technology to make real-world impacts. Lead with Innovation and Leadership Eli Lilly stands out in the marketplace by integrating deep industry expertise with robust research and development efforts. We are looking for professionals who are eager to drive change and lead the way in developing therapeutic breakthroughs. Explore Job Opportunities and Growth Eli Lilly offers a variety of career paths, including full-time positions and internships, across multiple functions such as research, marketing, IT, and sales. Whether you are a seasoned professional or a recent graduate, Eli Lilly provides an environment that promotes career growth and learning opportunities. Our commitment to diversity and leadership training ensures that every employee can achieve their potential. Be Part of Our Team Our team at Eli Lilly is committed to excellence and driven by a mission to improve lives. Employees enjoy a supportive culture that values collaboration, creativity, and diversity. We believe that a diverse workforce fosters innovation and helps us better connect with the communities we serve. Benefits and Culture Eli Lilly is dedicated to supporting our employees, offering competitive benefits, wellness programs, and comprehensive health care. Our culture is built on a foundation of respect, integrity, and quality, making Eli Lilly not just a great place to work, but a community to grow with. Networking and Professional Development Eli Lilly encourages continuous professional development and networking. With access to various training programs and mentorship opportunities, employees can enhance their skills and advance their careers. Our leadership is committed to nurturing talent through effective training and development strategies. Join Our Team Discover the exciting job opportunities at Eli Lilly by exploring open positions that match your skills and interests. We are continuously hiring and looking for individuals who are passionate, innovative, and ready to contribute to our mission of making life better for people around the globe. Stay Connected Keep up to date with the latest at Eli Lilly by following our careers blog. Gain insights from industry leaders and get tips on everything from crafting the perfect resume to preparing for your interview. Eli Lilly is not just a company—it's a place where you can make a difference. Explore the positions available and find out how your talents can help change the world. SEARCH ELI LILLY JOBS Stay ahead in your career with Eli Lilly, where innovation, leadership, and a commitment to diversity and growth lead the way to future advancements.
Learn more about Eli Lilly
Size
35,000 employees
Market Cap
$344.2 billion
Industry
Net Income
$6.1 billion
Founded
1876
5 Year Trend
+5.9%
Revenue
$24.5 billion
NASDAQ

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