Associate Principal Scientist - Biology

Neomorph, Inc.

$130K — $155K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD with 6+ years, MS with 9+ years, or BS with 11+ years of industry experience
  • Robust record in advancing preclinical drug discovery programs with solid data support
  • Experience in developing reproducible SAR-enabling assay cascades
  • Proven ability in team leadership and coaching
  • Experience with cross-functional team participation and leadership
  • Strong verbal/written communication skills
  • Ability to thrive in a fast-paced research environment

Responsibilities

  • Lead cross-functional teams to progress therapeutic candidates from discovery to clinical development
  • Independently develop and execute project-specific cellular assays to define mechanisms of action
  • Design triaging strategies to advance compound profiles based on deep biological understanding
  • Generate and lead new target nomination/identification/validation activities
  • Strategically respond to changes in the scientific or regulatory landscape
  • Communicate advancements and strategic shifts to stakeholders
  • Provide mentorship and share expertise with junior scientists

Benefits

  • Industry competitive compensation
  • Annual target bonus
  • Stock options
  • 401K plan
  • Career advancement opportunities
  • Comprehensive medical, dental, and vision plans
  • Health and Dependent Care FSA and HSA Plan
  • Employee Assistance Program
  • 10 holidays, Winter Shutdown, 3 weeks vacation with accruals after 2nd year
  • Paid Parental Leave and supplemental pay for pregnancy disability leave
  • Flexible work schedule
  • Access to onsite gym and bike/surfboard storage
  • Volunteer days off to support community causes
  • Social events and company culture focused on fun and work-life balance
Full Job Description
Position Overview

Neomorph is seeking an experienced drug discovery biologist with extensive experience participating in or leading programs through strategic, intellectual, and experimental contributions. The role will be critically involved in supporting Neomorph's growing pipeline by driving advancement of programs from early discovery through IND-enabling studies. The successful applicant will proactively collaborate across line functions to establish overarching project strategies and advance programs towards data-driven go/no go decisions.

Key Responsibilities

Participate in and/or lead cross-functional teams to advance therapeutic candidates from early discovery to clinical development through strategic prioritization, effective interdisciplinary collaboration, and efficient technical execution.

Lead from the bench - independently lead the development and execution of project-specific cellular assays to define target mechanism of action, assess markers of pharmacodynamic response, and identify relevant patient populations.

Design and implement effective triaging strategies to support SAR advancement and refinement of target compound profiles based on deep mechanistic understanding of underlying biology.

Generate and lead new target nomination/identification/validation activities that leverage unique aspects of the molecular glue degrader modality.

Anticipate, evaluate, and strategically respond to changes in scientific, competitive, or regulatory landscape.

Effectively communicate scientific advancements, strategic shifts, and risk assessments to project stakeholders.

Contribute to Neomorph's culture of scientific rigor, open collaboration, and continuous learning by openly sharing expertise and providing mentorship to junior scientists.

Required Qualifications
  • PhD with 6+ years, MS with 9+ years, or BS with 11+ years of industry experience
  • Track record of strategic, creative, and effective advancement of preclinical drug discovery programs supported by robust data packages
  • Demonstrated experience independently developing and implementing robust, reproducible SAR-enabling assay cascades supporting drug discovery programs
  • Experience successfully managing a team directing and coaching employees.
  • Experience participating in and/or leading cross-functional teams
  • Excellent verbal and written communication and interpersonal skills
  • Desire and capacity to participate in a dynamic and fast-paced research setting
  • Desire and capacity to work collaboratively as part of a multidisciplinary team

Preferred Qualifications
  • Experience with targeted protein degradation
  • Experience managing teams of one or more associate scientists


What we offer:
  • Industry competitive compensation
  • Annual target bonus
  • Stock options
  • 401K plan
  • Career advancement opportunities
  • Monthly town halls to share business and scientific updates


Work Hard, Stay Well
  • Comprehensive medical, dental, and vision plans for employees and their dependents
  • Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
  • Employee Assistance Program
  • 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
  • Supplemental pay for Pregnancy Disability Leave
  • Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care


Lifestyle
  • Casual work environment
  • Volunteer days off each year to spend time contributing to causes you care about
  • Flexible work schedule
  • Access to onsite gym
  • Onsite space to store your bicycle (or surfboard)


Have Fun!

We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).

Neomorph is headquartered in San Diego, California.

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