BillionToOne

Associate Director, Finance Systems

BillionToOne$192K — $235K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 4+ years in a SOX 404(b)-compliant environment managing IT General Controls or finance system compliance.
  • Experience working with Big 4 audit firms on control walkthroughs and audit evidence management.
  • 6+ years of hands-on administration of NetSuite and finance systems, including configurations and integrations.
  • Strong understanding of SOX ITGC domains and their application.
  • Proven experience in leading finance system implementations within a public company setting.
  • Bachelor's degree in Accounting, Finance, Information Systems, or related field.
  • Exceptional communication skills for presenting complex concepts to executives.

Responsibilities

  • Own and maintain the IT General Controls framework for financial systems.
  • Lead systems-related workstreams for annual SOX 404(b) audits with Big 4 auditors.
  • Serve as the main contact for external auditors on IT controls and documentation.
  • Oversee NetSuite system architecture and enhancements for compliance and efficiency.
  • Define and execute a multi-year financial systems roadmap focused on scalability.
  • Act as a strategic liaison among Finance, Accounting, HR, Legal, and IT for system alignment.
  • Manage vendor relations and contract negotiations for finance technology providers.

Benefits

  • Empowering work environment with dedicated colleagues striving for global change.
  • Open culture with weekly Town Hall meetings for transparency.
  • Opportunity to impact patient lives through innovative diagnostics.
  • Multiple healthcare options with significant premium coverage.
  • Generous Family Bonding Leave (16 weeks, fully paid).
  • Retirement savings program with 4% company match.
  • Increased paid time off based on tenure.
  • Access to the latest technology and office amenities.
  • Free on-site lunches from top eateries.
  • Comprehensive on-campus fitness and dining facilities.
Full Job Description
BillionToOne is seeking an Associate Director of Finance Systems to serve as the strategic and operational leader for all financial technology platforms across our organization. This is a senior individual contributor and people-leadership role that sits at the intersection of finance, compliance, and technology-responsible for ensuring our systems infrastructure is scalable, audit-ready, and aligned with the demands of a public company operating under SOX Section 404(b).

You will lead a team and act as the primary owner of our financial systems strategy, partnering closely with Accounting, Legal, HR, Billing, and IT to design and maintain a controlled environment that meets Big 4 audit scrutiny. Your deep experience with 404(b) compliance, ERP administration, and cross-functional system integrations will be foundational as BillionToOne continues to scale as a public company.

Responsibilities:
  • SOX 404(b) Compliance & Internal Controls
    • Own and maintain the company's IT General Controls (ITGCs) framework, including logical access, change management, and computer operations controls across all in-scope financial systems.
    • Lead all systems-related workstreams in support of the annual SOX 404(b) audit, coordinating directly with external auditors from Big 4 firms (Deloitte, PwC, EY, or KPMG).
    • Serve as the primary point of contact for external auditors on IT controls-prepare, review, and deliver all requested evidence, walkthroughs, and documentation.
    • Design and maintain control documentation, including risk and control matrices, narratives, and process flowcharts for all financially relevant systems.
    • Partner with internal audit and outside advisors to proactively identify and remediate control gaps and deficiencies before audit fieldwork.
    • Drive continuous improvement of the internal controls environment as the company grows and systems evolve.
  • ERP & Financial Systems Strategy
    • Serve as the senior system owner for NetSuite, overseeing system architecture, configurations, workflows, roles, permissions, and release management.
    • Define and execute the multi-year financial systems roadmap, identifying technology investments that support scalability, compliance, and operational efficiency.
    • Oversee evaluation, selection, and implementation of new financial technology platforms including revenue management, payment systems, FP&A tools, and HRIS integrations.
    • Establish and enforce change management policies, including change request processes, UAT protocols, and go-live approval gates.
    • Drive automation and process optimization initiatives across the finance and supply chain systems landscape.
  • Cross-Functional Leadership & Stakeholder Partnership
    • Act as the strategic liaison between Finance, Accounting, HR, Legal and IT, ensuring system design and project delivery align with operational needs and compliance requirements.
    • Lead and mentor a team of Finance Systems analysts and administrators, setting clear goals, priorities, and professional development plans.
    • Partner with the Controller and CFO to ensure systems readiness for monthly close, quarterly reporting, and audit cycles.
    • Develop and maintain executive-level reporting on system health, project status, and risk exposure.
    • Manage vendor relationships for key finance technology providers, including contract negotiations and performance reviews.
  • Audit Readiness & Documentation
    • Maintain comprehensive IT SOX documentation including control descriptions, testing evidence, and remediation tracking across all audit cycles.
    • Prepare systems-level audit responses and coordinate responses to auditor requests with speed and precision.
    • Ensure all financial systems provide full traceability, data integrity, and documentation required for external reporting and audit.
    • Partner with the SEC reporting and technical accounting teams to ensure systems support accurate financial disclosures.

Qualifications:
  • 4+ years of experience working within a SOX Section 404(b)-compliant public company environment, with direct responsibility for IT General Controls or finance systems compliance.
  • Demonstrated experience working at or directly with Big 4 audit firms (Deloitte, PwC, EY, or KPMG) in a public company context-including leading control walkthroughs, providing audit evidence, and managing deliverable timelines.
  • 6+ years of hands-on NetSuite and other Finance system administration experience, including complex configurations, workflow automation, role design, and integration management.
  • Deep understanding of SOX ITGC domains: logical access, change management, computer operations, and their application across financially relevant systems.
  • Proven track record leading end-to-end finance systems implementations and technology projects in a public company setting.
  • Bachelor's degree in Accounting, Finance, Information Systems, Computer Science, or a related field.
  • Strong command of financial operations, close processes, internal controls frameworks (COSO, COBIT), and audit methodologies.
  • Experience with SOX-relevant systems including HRIS, equity management platforms, and related revenue recognition systems.
  • Exceptional written and verbal communication skills; ability to present complex controls and systems topics clearly to executive audiences and external auditors.
  • Proven ability to lead, develop, and retain a team in a fast-paced, high-growth environment.
  • Highly detail-oriented with a track record of delivering accurate, audit-quality documentation.

Nice-To-Haves:
  • CPA, CISA, or relevant systems/audit certification.
  • Experience managing a transition from 404(a) to 404(b) compliance, including readiness assessments and external auditor onboarding.
  • Familiarity with data integration and middleware tools (e.g., MuleSoft, Boomi, Workato).
  • Experience with ADP Workforce Now or other enterprise HRIS platforms.
  • Exposure to SEC reporting cycles and working with investor relations or technical accounting teams.
  • Experience in a diagnostics, biotech, or healthcare company navigating financial and regulatory compliance.

Benefits And Perks:
  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Free daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, (2) the opportunity for professional growth, and (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).

For this position, we offer a total compensation package of $376,177 per year, including a base pay range of $192,932 - $235,806 per year.

About BillionToOne

BillionToOne is a biotechnology company that develops molecular diagnostics for genetic diseases. The company's platform, called the QCT molecular counter, uses a proprietary technology to detect rare mutations in DNA samples. BillionToOne's technology is used in prenatal testing, cancer diagnostics, and other applications. The company was founded in 2016 and is headquartered in San Francisco, California.
Learn more about BillionToOne
Size
10 employees
Industry
Founded
2016

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