Arrowhead Research

Analyst II, Information Security

Arrowhead Research$85K — $100K *
Information Technology
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Information Security, IT, Computer Science, or related field, or equivalent experience
  • 3+ years in Information Security, System Administration, Help Desk, or similar roles
  • Experience with MDM/MAM policies for various operating systems
  • Hands-on experience administering EDR platforms like Microsoft Defender
  • Experience in regulated industry environments
  • Strong analytical skills for investigating security alerts and audit logs
  • Effective communication skills for explaining technical concepts to non-technical stakeholders

Responsibilities

  • Create secure endpoint configuration baselines using Group Policy or Intune
  • Triage and escalate security alerts as needed
  • Develop, test, and deploy conditional access policies
  • Maintain and troubleshoot firewall security policies
  • Participate in audits to ensure compliance with security practices
  • Standardize Intune compliance policies and device configurations
  • Coordinate with IT to enhance user experience while maintaining security controls
  • Monitor and remediate endpoint configuration compliance
  • Contribute to Microsoft Entra ID hardening initiatives
  • Automate tasks and checks using PowerShell and Intune scripts
  • Maintain documentation and contribute to the knowledge base

Benefits

  • Competitive salaries
  • Excellent benefits package
  • Opportunities for professional growth and development
Full Job Description
The Position

We're seeking an Information Security Analyst with a strong foundation in Help Desk or System Administration and expertise in Microsoft Intune, or Defender. You'll design, implement, and maintain secure endpoint baselines, enforce configuration and compliance, and collaborate closely with IT operations to reduce risk and improve our security posture. This role is ideal for someone who has worked extensively with Windows and Microsoft 365 administration, enjoys solving complex configuration problems, and wants to grow their impact on information security.

Responsibilities
  • Create secure endpoint configuration baselines via Group Policy or Intune based on published security frameworks (NIST, CIS, etc.)
  • Triage security alerts and escalate as necessary.
  • Create, test, and deploy conditional access policies.
  • Create, maintain, and troubleshoot firewall security policies.
  • Participate in regular audits to ensure security practices are compliant with company policies and applicable laws.
  • Standardize and enforce Intune compliance policies, device configuration profiles, and remediation scripts.
  • Coordinate with IT to minimize user friction while maximizing control (test rings, staged rollouts, rollback plans).
  • Monitor endpoint configuration compliance and remediate drift.
  • Contribute to Microsoft Entra ID hardening: Conditional Access, MFA configuration, device compliance gates, role-based access, Privileged Identity Management (PIM).
  • Use PowerShell and/or Intune remediation scripts to automate repetitive tasks, reporting, and configuration drift checks.
  • Maintain clear documentation (runbooks, diagrams, standards, exceptions) and contribute to a knowledge base.

Requirements
  • Bachelor's degree in Information Security, Information Technology, Computer Science, or a related field, or equivalent practical experience
  • 3+ years of experience in Information Security, System Administration, Help Desk, or similar roles
  • Exposure to MDM/MAM policies for Windows/macOS/iOS/Android
  • Demonstrated hands-on experience administering EDR (Microsoft Defender, Crowdstrike Falcon, Sentinel One)
  • Experience working within or supporting a regulated industry environment
  • Strong analytical and problem-solving skills with the ability to investigate alerts, interpret audit logs, and distinguish signal from noise
  • Effective written and verbal communication skills, with the ability to explain technical concepts to non-technical stakeholders

Preferred
  • Cybersecurity experience in an OT or manufacturing environment
  • Experience with Dragos OT security
  • Certifications relevant to security and compliance
  • Prior experience in the pharmaceutical, biotech, or life sciences sector
  • Exposure to SIEM tools, endpoint detection and response (EDR) platforms, or identity and access management systems
  • Exposure to Intune device configurations and MDM Policies
  • Experience in GxP environments


Wisconsin pay range

$85,000-$100,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

California Applicant Privacy Policy

About Arrowhead Research

Arrowhead Research is a biotechnology company that develops RNA interference (RNAi) therapeutics. The company was founded in 2007 and is headquartered in Pasadena, California. Arrowhead's RNAi technology targets specific genes to silence their expression, which can be used to treat a variety of diseases. The company's pipeline includes treatments for liver disease, cancer, and cardiovascular disease. Arrowhead has partnerships with pharmaceutical companies such as Amgen and Janssen Pharmaceuticals. The company has received FDA approval for some of its products and is conducting clinical trials for others.
Learn more about Arrowhead Research
Size
329 employees
Market Cap
$4 billion
Industry
Net Income
-$102.6 million
Founded
2004
5 Year Trend
+50.6%
Revenue
$79.8 million
NASDAQ

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