Ai Biologist - Rare Disease

LatchBio

• $120K — $180K *
US-AnywhereRemote in San Francisco, CA
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's, PhD, or equivalent experience in a biological or quantitative field
  • 3+ years hands-on experience in basic or translational research, clinical genomics, or rare disease therapeutics
  • Deep expertise in therapeutics discovery and clinical practice in rare diseases
  • Experience interpreting biological data and identifying technical artifacts
  • Proficiency in Python/R for biological data analysis

Responsibilities

  • Structure and curate extensive datasets including genomic and clinical data
  • Navigate data partnerships with external sources
  • Evaluate patient case scenarios throughout the diagnostic journey
  • Collaborate with software engineers on data workflows
  • Contribute to the research and strategy on rare disease agents

Benefits

  • 1099 or W8-BEN contract with no end date
  • Fully performance-based pay with uncapped upside
  • 2-4 week paid ramp with full on-target earnings from day one
  • Flexible work location options (remote, hybrid, or onsite)
  • Onsite perks including meals, waterfront office, and parking availability
Full Job Description
AI Biologist - Rare Disease

As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry.

We're seeking an AI Biologist to join our Rare Disease team to explore the frontier of what AI assistance can enable in rare disease biology.

About the Role

You will contribute to Latch's benchmarks, strategy, and research on agents that can navigate, diagnose, and aid research toward rare disease. We are especially interested in teaching agents to translate molecular and clinical evidence into decisions with utility for patients, advocacy groups, clinicians, drug developers, and scientists. Some of what you may do on the day to day:
  • Structure, curate, and find insights from extensive genomic, phenotypic, pedigree, transcriptomic, and longitudinal clinical data
  • Navigate data partnerships
  • Evaluate realistic patient case scenarios spanning the diagnostic journey
  • Partner with software engineers to define and execute new data workflows and benchmarks

Requirements
  • Master's, PhD, or equivalent experience in a relevant biological or quantitative field
  • 3+ years hands-on experience in basic or translational research, clinical genomics, rare disease diagnostics, or rare disease therapeutics, ideally as demonstrated through publications or industry work
  • Deep expertise with therapeutics discovery, biological mechanism, or clinical practice in a subset of rare diseases
  • Experience interpreting data in biological context and identifying confounders, technical artifacts, and limitations of underlying experiments
  • Proficiency in Python/R for biological data analysis or visualization


Nice to Have
  • Experience with variant interpretation, variant calling, or genomic analysis
  • Familiarity with commonly used rare disease knowledge bases and workflows
  • Proficiency in AI agent use


Compensation & Logistics
  • 1099 (or W8-BEN) contract, 40 hrs/week, no end date
  • Fully performance-based pay: $120K-$180K, uncapped upside. 2x quota = 2x pay.
  • 2-4 week paid ramp - full OTE from day one
  • Remote (globally), hybrid, or onsite in SF (onsite preferred)
  • Work authorization: OPT visa holders only (not STEM Extension)
  • Onsite perks: 2x free meals/day, waterfront office (China Basin), monthly parking (based on availability)
  • Candidates with all of the above qualifications + proven management skills will be eligible for more senior positions

Interview Process

Timeline: We move fast: 8-12 days from submission to offer.
  1. Intro Screen - Technical Recruiter
  2. Take-Home Project - HackerRank
  3. Technical Interview - Member of Technical Staff
  4. Culture Interview - C-Suite (If applicable)
  5. Offer

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