A helix (pl: helixes or helices) is a type of smooth space curve, i.e. a curve in three-dimensional space. It has the property that the tangent line at any point makes a constant angle with a fixed line called the axis. Examples of helices are coil springs and the handrails of spiral staircases. A "filled-in" helix – for example, a spiral ramp – is called a helicoid. Helices are important in biology, as the DNA molecule is formed as two intertwined helices, and many proteins have helical substructures, known as alpha helices. The word helix comes from the Greek word ????, "twisted, curved". Helices can be either right-handed or left-handed. With the line of sight along the helixs axis, if a clockwise screwing motion moves the helix away from the observer, then it is called a right-handed helix; if towards the observer, then it is a left-handed helix. Handedness (or chirality) is a property of the helix, not of the perspective: a right-handed helix cannot be turned to look like a left-handed one unless it is viewed in a mirror, and vice versa. Most hardware screw threads are right-handed helices. The alpha helix in biology as well as the A and B forms of DNA are also right-handed helices. The Z form of DNA is left-handed.