Guidehouse

Technical SETA SME - Biotech

Guidehouse$149K — $248K *
US-AnywhereRemote in United States
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Active Top Secret SCI clearance with polygraph required
  • PhD in a STEM field
  • Minimum of 2 years experience in STEM
  • Experience with the Intelligence Community is a plus
  • Proficient in writing and editing for technical documentation

Responsibilities

  • Provide unbiased engineering expertise across system lifecycle
  • Review contractor technical deliverables for compliance
  • Support development and management of requirements
  • Assist in program planning and risk management
  • Develop technical documentation such as specifications and test plans
  • Conduct readiness assessments and facilitate stakeholder communication
  • Identify risks and make recommendations to leadership

Benefits

  • Medical, Rx, Dental & Vision Insurance
  • Paid Sick Time & Holidays
  • Potential discretionary variable incentive bonus
  • Parental Leave and Adoption Assistance
  • 401(k) Retirement Plan
  • Basic Life & Supplemental Life Insurance
  • Flexible Spending Accounts for healthcare and dependent care
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement and Skills Development
  • Employee Referral Program and Community Outreach events
  • Emergency Back-Up Childcare Program
  • Mobility Stipend
Full Job Description

Job Family:

Operational Effectiveness (ESA)


Travel Required:

Up to 10%


Clearance Required:

Active Top Secret SCI with Polygraph

What You Will Do:

A Technical SETA provides independent, objective systems engineering and technical expertise to government program offices, ensuring programs are planned, designed, and executed effectively. This role supports the government as a trusted advisor rather than a contractor developing deliverables, focusing on technical rigor, acquisition support, and mission alignment.

Key Responsibilities

  • Provide unbiased systems engineering expertise across the full system lifecycle, including concept development, architecture design, integration, testing, deployment, and sustainment.

  • Review, analyze, and validate contractor technical deliverables, ensuring compliance with requirements, standards, and mission needs.

  • Support requirements development and management, including traceability, verification methods, and acceptance criteria.

  • Assist with program planning, acquisition strategies, risk management, scheduling, and technical baseline reviews.

  • Develop and evaluate technical documentation such as interface control documents, system specifications, test plans, and engineering analyses.

  • Support readiness assessments, design reviews, technical interchange meetings, and decision gates.

  • Identify risks, issues, and opportunities and provide recommendations to government leadership.

  • Conduct independent research, trade studies, and market assessments to inform program decisions.

  • Ensure technical alignment with enterprise architectures, security policies, and cross-program integrations.

  • Facilitate communication among stakeholders, including government customers, contractors, and mission partners.

Guidehouse is currently looking for experts with experience in one or more of the following for these Technical SETA SME roles:

  • Waveform & RF Communications

  • Wireless Communications Systems

  • Artificial Intelligence (AI) & Machine Learning (ML)

  • Modeling & Simulation (M&S)

  • Quantum Computing

  • Advanced Platforms & Systems Integration

  • Computer Vision & Sensing Technologies

  • Microelectronics & Next-Gen Hardware

** These roles require 5-days a week on client site in Bethesda, MD.

What You Will Need:

  • An ACTIVE and MAINTAINED TS/SCI Federal or DoD securityclearance with a polygraph

  • PhD in science, technology, engineering, or mathematics field

  • TWO (2) or more years of experience in science, technology, engineering or mathematics

What Would Be Nice To Have:

  • ONE (1) year of experience in the Intelligence Community (IC), including experience with requirements, CONOPS, and transition

  • Excellent writing/editing skills

  • Excellent slide development/PowerPoint skills

  • Strong organizational, problem-solving, and time management skills

  • Ability to manage multiple concurrent tasks

The annual salary range for this position is $149,000.00-$248,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.


What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

  • Medical, Rx, Dental & Vision Insurance

  • Personal and Family Sick Time & Company Paid Holidays

  • Position may be eligible for a discretionary variable incentive bonus

  • Parental Leave and Adoption Assistance

  • 401(k) Retirement Plan

  • Basic Life & Supplemental Life

  • Health Savings Account, Dental/Vision & Dependent Care Flexible Spending Accounts

  • Short-Term & Long-Term Disability

  • Student Loan PayDown

  • Tuition Reimbursement, Personal Development & Learning Opportunities

  • Skills Development & Certifications

  • Employee Referral Program

  • Corporate Sponsored Events & Community Outreach

  • Emergency Back-Up Childcare Program

  • Mobility Stipend

About Guidehouse

Guidehouse is a management consulting firm headquartered in Washington, D.C. The firm provides consulting services to clients in the public and commercial sectors, with a focus on energy, financial services, healthcare, national security, and aerospace and defense. Guidehouse was founded in 2018 as a spin-off from PwC. The firm has over 7,000 employees and operates in more than 50 locations worldwide.
Learn more about Guidehouse
Size
8,000 employees
Industry
Founded
2018

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