AstraZeneca

Sr Director, US Medical Early Assets – Insights

AstraZeneca$175K — $210K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree required; advanced degree preferred (e.g., MBA, MPH, MS in Market Research/Statistics, PharmD)
  • 8+ years in pharma/biotech or consulting, focused on market insights and early commercial strategy; US market experience necessary
  • Proven impact in shaping TPPs and influencing clinical plans
  • Experience developing data and analytics strategies in complex team environments
  • Exceptional skills in executive communication and influencing decision-makers
  • Ability to align diverse stakeholders towards a strategic direction

Responsibilities

  • Define the US insights learning plan and prioritize unknowns across asset stages
  • Design and lead qualitative and quantitative market research studies
  • Synthesize secondary analytics and treatment paradigms to identify market opportunities
  • Maintain competitive intelligence profiles and conduct simulations
  • Pressure-test TPP elements and recommend trade-offs for maximum value
  • Build early demand forecasts and scenario analyses in partnership with Finance
  • Translate insights into guidance for trial design and US market adoption

Benefits

  • In-person working model to foster collaboration and innovation
  • Minimum of three days per week in the office with flexibility for team members
  • Opportunity to contribute to life-changing medicines and ambitious medical strategies
Full Job Description

Sr Director, US Medical Early Assets – Insights 

Reporting directly to the Executive Director, US Medical Early Asset Team Lead, you will be part of a team focused on the development of ambitious US medical strategies for our early pipeline. This is an opportunity to seize, design, and influence across a complex matrix system to ensure US needs are integrated into global development plans. 

Accountabilities:
Sr Director, US Medical Early Asset – Insights will own US insight generation and decision analytics for pipeline assets from late discovery through Phase 2. You will translate ambiguity into clear, evidence-based recommendations by integrating secondary analytics, custom market research, competitive intelligence, epidemiology, and early forecasting. Partnering closely with Global/US Commercial, Medical, Clinical Development, Market Access, HEOR, and Finance, you will shape target product profiles, influence trial design, pressure-test differentiation hypotheses, and inform investment decisions at stage gates. 

Key Responsibilities 

  • Insight Strategy and Roadmap: Define the US insights learning plan across asset stages; prioritize critical unknowns and decision points, and map research/analytics to governance milestones. 
  • Primary Market Research: Design and lead payer/HCP/patient qualitative and quantitative studies (concept tests, message/value testing, conjoint/DTU, ethnography, discrete choice, max-diff) to refine positioning and evidence needs. 
  • Secondary Analytics: Synthesize syndicated data, claims/EMR analyses, epidemiology, treatment paradigms, and policy trends to size opportunities, refine segmentation, and anticipate adoption barriers. 
  • Competitive Intelligence: Maintain dynamic competitor profiles, trial readouts, label trajectories, and access precedents; run competitor simulations and implications for differentiation and timing. 
  • Target Product Profile and Asset Shaping: Pressure-test TPP elements (endpoints, attributes, device/format, administration setting, line of therapy, subsegments) via research and rapid experiments; recommend trade-offs to maximize US value. 
  • Early Forecasting and Scenarios: Build and refine early demand/adoption forecasts, market maps, and scenario trees; partner with Finance on rNPV and sensitivity analyses that reflect uncertainty and key inflection points. 
  • Evidence and Trial Design Input: Translate insight into guidance on endpoints, comparators, PROs, inclusion/exclusion, and RWE priorities that support future US adoption, labeling, and access. 
  • Customer and Ecosystem Mapping: Identify priority segments (HCPs, treatment centers, IDNs, payers, patient pathways) and define decision drivers across the care continuum to inform early brand strategy and initial field teams' structure. 
  • Value Proposition Development: Co-create early value narratives and differentiation hypotheses; test resonance and credibility with customers and iterate with Medical/HEOR and Market Access. 
  • Rapid Test-and-Learn: Stand up lightweight experiments (concept sprints, ad boards, rapid quant) to answer time-sensitive questions ahead of governance gates and external catalysts. 
  • Communications and Governance: Craft clear, concise readouts and recommendations for asset teams and governance; ensure traceability from insight to decision and document assumptions/risks. 
  • Vendor and Budget Management: Select and manage research/analytics vendors; ensure methodological rigor, compliance, and on-time, on-budget delivery. 
  • Compliance and Ethics: Conduct research and external engagements in line with US regulations and company policies for pre-approval communications and data privacy. 

Minimum Qualifications

  • Bachelor’s degree required; advanced degree preferred (MBA, MPH, MS in Market Research/Statistics, PharmD, or related). 
  • 8+ years in pharma/biotech or consulting focused on market insights, new product planning, or early commercial strategy; US market experience required; early development experience (Phase 1–2) strongly preferred. 
  • Demonstrated impact shaping TPPs, influencing clinical/evidence plans, and informing investment decisions via robust insights and analytics. 
  • Significant experience developing enterprise data and analytics strategies, navigating complex matrix teams, and translating emerging insights into business-critical decisions across multiple therapeutic areas, assets, or portfolios.
  • Exceptional executive communication and influencing skills, with the ability to translate complex analytics, assumptions, risks, and uncertainties into clear strategic recommendations for senior leadership, governance bodies, and cross-functional decision-makers (Clinical, Medical, Market Access/HEOR, and Finance)
  • Demonstrated capability to align diverse stakeholders around a common strategic direction and drive action in highly matrixed environments.

Preferred Qualifications

  • Hands-on experience with qualitative and quantitative methods (e.g., conjoint/DCE, segmentation, ATU/DTU, message testing) and vendor oversight. 
  • Proficiency with forecasting basics, epidemiology inputs, claims/EMR analytics, and triangulation across data sources; comfort with uncertainty and sensitivity testing. 
  • Ability to translate competitor clinical and access moves into implications for positioning and evidence. 
  • Working knowledge of analytics and visualization tools (e.g., Excel, PowerPoint; familiarity with data platforms/BI tools is a plus). 
  • Practical experience using AI/ML-enabled tools for insights work (e.g., NLP for unstructured text, predictive modeling, synthetic respondent methods, automated coding of qual, prompt engineering for analysis/synthesis) with an understanding of data privacy, bias, and validation best practices. 

This position is based at our Wilmington, DE campus headquarters for our US Biopharma business. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious. 

Next Steps – Apply Today!

Are you ready to make a difference? Apply now and join our mission to transform lives with our science! 

Date Posted

01-Sept-2026

Closing Date

14-Sept-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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