Glaukos

Sr. Applied Research Engineer - OCE - Burlington MA

Glaukos$100K — $130K *
Healthcare
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Biomedical Engineering, Mechanical Engineering, Optical Engineering, Physics, or related field, or equivalent experience with MS/Bachelor's.
  • 5-8+ years of experience in developing biomechanical assays and imaging systems; 3-5 years with MS or 0-4 years with PhD.
  • Experience in elastography and quantitative tissue characterization techniques, ideally within regulated medical environments.
  • Strong background in experimental system development, including hardware-software integration.
  • Expertise in signal processing and algorithm development for imaging data.
  • Proficiency in Python and familiarity with C++, C#, or other programming languages is a plus.
  • Excellent written and verbal communication skills.

Responsibilities

  • Contribute to design and development of ophthalmic medical devices, from research to translational development.
  • Design, implement, and experimentally evaluate corneal imaging modalities and elastography approaches.
  • Implement and optimize biomechanical imaging and elastography-based techniques to assess corneal properties.
  • Develop and refine experimental biomechanical imaging systems and data acquisition hardware.
  • Create and maintain algorithms and software pipelines for biomedical imaging data processing.
  • Ensure robustness and performance of processing pipelines across varied experimental conditions.
  • Collaborate with engineering teams to integrate algorithms into medical device prototypes.

Benefits

  • Collaborative work environment within a team of skilled professionals.
  • Opportunities for advancing next-generation ophthalmic technologies.
  • Engagement in meaningful translational research that impacts patient care.
  • Chance to contribute to publications and patents.
Full Job Description
Job Description

Job Description:

We are seeking a highly motivated and experienced scientist or engineer to join our Applied Research team and contribute to the advancement of next-generation technologies within our Corneal Health (CH) product portfolio. This role will play a central part in driving early-stage innovation, technology development, and translational research efforts aimed at expanding the capabilities and clinical impact of our ophthalmic medical device platforms.

The successful candidate will work at the intersection of experimental science, engineering, and clinical translation to develop new technologies and methodologies. A key focus of this role will be designing, implementing, and translating imaging, and computational approaches that enable improved understanding and quantification of corneal structure and biomechanics.

The ideal candidate will bring deep expertise spanning experimental system development, signal processing and algorithm design, and biomechanical modeling, with a strong interest in translating research concepts into robust, validated technologies.

Responsibilities

Responsibilities:
  • Contribute to the design and development of current and next-generation ophthalmic medical devices, from early research through translational development.
  • Design, implement, and experimentally evaluate different corneal imaging modalities and elastography approaches, including comparative performance analysis, sensitivity, repeatability, and clinical relevance, to inform system design and future technology directions.
  • Design, develop, implement, and optimize advanced biomechanical imaging and elastography-based techniques to assess corneal biomechanical properties and their changes due to therapeutic interventions (e.g., crosslinking treatments).
  • Develop, maintain, and refine experimental biomechanical imaging systems, including imaging subsystems, excitation mechanisms, data acquisition hardware, synchronization, and system calibration procedures.
  • Develop, optimize, and maintain processing and post-processing algorithms and software pipelines for biomedical imaging data.
  • Ensure robustness, reproducibility, and performance of processing pipelines across experimental conditions, system configurations, and datasets.
  • Collaborate closely with hardware, software, and systems engineering teams to integrate algorithms and experimental methods into prototype and product-level medical devices.
  • Oversee data collection, preprocessing, algorithm development, validation, and performance characterization through rigorous experimental testing.
  • Design controlled experiments, phantoms, and validation protocols to compare system performance and biomechanical measurement techniques.
  • Communicate technical results clearly through design reviews, internal reports, and technical documentation; contribute to publications, patents, or regulatory submissions as appropriate.


Qualifications

Work Experience:
  • PhD in Biomedical Engineering, Mechanical Engineering, Optical Engineering, Physics, or a related field, or MS/Bachelor's degree with equivalent industry experience.
  • 5-8+ years of relevant experience (3-5+ years with an MS degree or 0-4+ years with a PhD) developing biomechanical assays, experimental imaging systems, and quantitative analysis algorithms.
  • Demonstrated experience with elastography, biomechanical imaging, or quantitative tissue characterization techniques in research or commercial environments; experience in regulated medical device settings is a strong plus.
  • Strong background in experimental system development, including imaging system design, hardware-software integration, and measurement system validation.
  • Expertise in signal processing and algorithm development for imaging data.
  • Strong programming skills in Python or similar scientific programming languages; experience with C++, C#, or other systems-level programming languages is a plus.
  • Experience developing maintainable, well-documented scientific software and transitioning research code into robust implementations is a plus.
  • Familiarity with medical imaging, ophthalmic technologies, or related biomedical applications.
  • Experience working with medical device regulations, standards, and technical documentation for regulatory submissions is a strong plus.
  • Familiarity with machine learning or statistical learning applied to imaging or biomechanical data is a plus.
  • Excellent written and verbal communication skills, with the ability to collaborate effectively across disciplines and levels of the organization.

#GKOSUS

About Glaukos

Glaukos Corporation is an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases. The company pioneered Micro-Invasive Glaucoma Surgery, or MIGS, to revolutionize the traditional glaucoma treatment and management paradigm. Glaukos launched the iStent, its first MIGS device, in the United States in 2012 and is leveraging its platform technology to build a comprehensive and proprietary portfolio of micro-scale injectable therapies designed to address the complete range of glaucoma disease states and progression. The company's second-generation MIGS device, the iStent inject, was approved by the FDA in June 2018. Glaukos is also developing a pipeline of innovative technologies in corneal health, including the recently acquired Microline surgical platform, as well as novel drug delivery technologies.
Learn more about Glaukos
Size
727 employees
Market Cap
$1.9 billion
Industry
Net Income
-$120.3 million
Founded
1998
5 Year Trend
+20.8%
Revenue
$224.9 million
NASDAQ

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