Astellas Pharma US, Inc

Setidegrasib Launch Lead (NSCLC), US Oncology

Astellas Pharma US, Inc$161K — $243K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree required.
  • Extensive U.S. pharmaceutical or biotechnology commercial experience, particularly in oncology marketing, launch planning, or brand strategy.
  • Experience in U.S. product launch preparation, including integrated launch planning and execution.
  • In-depth understanding of the U.S. oncology market dynamics, including HCP engagement and payer considerations.
  • Strong capability to convert insights into actionable commercial plans and launch execution priorities.
  • Proven leadership of cross-functional teams and ability to influence senior stakeholders.
  • Knowledge of pharmaceutical compliance requirements and ability to ensure adherence.

Responsibilities

  • Develop and execute the U.S. commercial launch strategy for setidegrasib in NSCLC.
  • Translate key insights into brand priorities and commercial recommendations.
  • Shape brand positioning, messaging, and core launch materials with multiple partners.
  • Lead launch readiness efforts across various workstreams, ensuring alignment with company standards.
  • Create engagement strategies for external stakeholders, including HCPs and patient organizations.
  • Collaborate with market access and account teams for effective launch planning.
  • Establish metrics and performance monitoring for early launch evaluation and optimization.

Benefits

  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off including national holidays and year-end shutdown
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program
Full Job Description
Setidegrasib Launch Lead (NSCLC), US Oncology

Purpose & Scope

The U.S. Setidegrasib Launch Lead, NSCLC is responsible for leading U.S. commercial launch strategy and execution readiness for setidegrasib (A3082) in non-small cell lung cancer, a key oncology pipeline asset. This role will partner closely with cross-functional teams and co-creation affiliates to shape insight-driven launch plans, stakeholder engagement strategies, and commercial priorities that support a competitive U.S. launch and maximize long-term brand value. Responsibilities may evolve beyond NSCLC based on brand and business needs.

Role and Responsibilities
  • Develop and lead the U.S. commercial launch strategy and integrated launch plan for setidegrasib in NSCLC, including launch objectives, critical success factors, key milestones, governance, and cross-functional execution roadmap.
  • Translate patient, customer, scientific, biomarker/testing, pathway, market access, and competitive insights into clear brand priorities, business recommendations, and launch execution choices.
  • Shape U.S. brand positioning, messaging, and core launch materials in partnership with medical, legal, regulatory, market access, sales, training, agency, and global/co-creation partners.
  • Lead cross-functional launch readiness across key workstreams, including marketing, medical, access, sales, training, analytics, diagnostics/biomarker strategy, operations, and supply, ensuring alignment with Astellas launch excellence expectations.
  • Develop external stakeholder and customer engagement strategies for priority audiences, including HCPs, key external experts, patient advocacy organizations, pathways, accounts, and other relevant oncology stakeholders.
  • Partner with market access and account teams to support pricing, reimbursement, payer, distribution/channel, and account-level launch planning for the U.S. market.
  • Establish launch performance metrics, dashboards, feedback loops, and business review cadence to monitor readiness and early launch performance, identify risks, and optimize execution.
  • Ensure all launch planning and external engagement activities comply with Astellas policies, Ethics and Compliance standards, and applicable laws and regulations governing interactions with HCPs, HCOs, and patient organizations.


Required Qualifications
  • Bachelor's degree required
  • Significant U.S. pharmaceutical or biotechnology commercial experience, with demonstrated success in oncology marketing, launch planning, or brand strategy.
  • Direct experience supporting or leading U.S. product launch preparation, including integrated launch planning, cross-functional readiness, customer strategy, and launch execution.
  • Strong understanding of the U.S. oncology market, including HCP engagement, treatment pathways, biomarker/testing dynamics, payer/access considerations, and the competitive landscape.
  • Proven ability to translate market, customer, patient, scientific, and competitive insights into clear strategic choices, commercial plans, and executional priorities.
  • Demonstrated ability to lead cross-functional teams and influence senior stakeholders across marketing, medical, market access, sales, regulatory, legal, analytics, and global partners.
  • Strong knowledge of pharmaceutical industry compliance requirements and ability to ensure activities are conducted in accordance with company policies and applicable laws and regulations.


Preferred Qualifications
  • U.S. commercial experience in Lung Cancer
  • HCP Marketing experience


Location and Working Environment

This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.

At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas' Responsible Flexibility Guidelines.

Salary Range

$161,928 - $243,500 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)Flexible pay grade level based on candidate background and skillset.

Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program


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About Astellas Pharma US, Inc

Astellas Pharma US, Inc is a pharmaceutical company that develops and markets drugs for the treatment of cancer, immunology, and urology. The company is a subsidiary of Astellas Pharma Inc, a Japanese pharmaceutical company. Astellas Pharma US, Inc was founded in 2005 and is headquartered in Northbrook, Illinois. The company has over 17,000 employees and operates in over 50 countries. Astellas Pharma US, Inc is committed to improving the health and well-being of patients through the development of innovative and effective therapies.
Learn more about Astellas Pharma US, Inc
Size
14,522 employees
Industry
Founded
2005
NASDAQ

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